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Clinuvel PharmaceuticalsCLVLF 87 EV-to-EBITDA is 4.77 as of Aug. 02, 2026, which is 83% below its 10-year median of 27.33. GuruFocus rates CLVLF with a GF Score™ of 87/100 and a GF Value™ of $12.49 (Significantly Undervalued). The stock has 2 warning signs investors should review. Among 411 Biotechnology companies, Clinuvel Pharmaceuticals ranks better than 64.72% on this metric.
EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Clinuvel Pharmaceuticals's enterprise value is $157.49 Mil.
Clinuvel Pharmaceuticals's EBITDA for the trailing twelve months (TTM) ended in Dec. 2025 was $32.99 Mil. Therefore, Clinuvel Pharmaceuticals's EV-to-EBITDA for today is 4.77.
The historical rank and industry rank for Clinuvel Pharmaceuticals's EV-to-EBITDA or its related term are showing as below:
CLVLF'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -96.75 Med: 27.33 Max: 153.64
Current: 4.46
During the past 13 years, the highest EV-to-EBITDA of Clinuvel Pharmaceuticals was 153.64. The lowest was -96.75. And the median was 27.33.
CLVLF's EV-to-EBITDA is ranked better than 64.72% of 411
companies
in the Biotechnology industry
Industry Median: 12.05
vs CLVLF: 4.46
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Clinuvel Pharmaceuticals's PE Ratio (TTM) for today is calculated as:
Clinuvel Pharmaceuticals's share price for today is $6.37.
For company reported semi-annually, GuruFocus uses latest annual data as the TTM data. Clinuvel Pharmaceuticals's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Dec. 2025 was $0.422.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
CLVLF vs VRTX, REGN, RVMD: EV-to-EBITDA Comparison
For the Biotechnology subindustry, Clinuvel Pharmaceuticals's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Clinuvel Pharmaceuticals EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Clinuvel Pharmaceuticals's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Clinuvel Pharmaceuticals's EV-to-EBITDA falls into.
Clinuvel Pharmaceuticals's current Enterprise Value is $157.49 Mil.
For company reported semi-annually, GuruFocus uses latest annual data as the TTM data. Clinuvel Pharmaceuticals's EBITDA for the trailing twelve months (TTM) ended in Dec. 2025 was $32.99 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Clinuvel Pharmaceuticals (CLVLF) has a EV-to-EBITDA of 4.77 as of Aug. 02, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Clinuvel Pharmaceuticals. This is 83% below median its historical median of 27.33. According to the industry distribution chart, Clinuvel Pharmaceuticals ranks #145 out of 411 companies in the Biotechnology industry, placing it in the top 35.3%.
Is Clinuvel Pharmaceuticals' EV-to-EBITDA too high?
Clinuvel Pharmaceuticals' current EV-to-EBITDA of 4.77 is 83% below median its 10-year median of 27.33. The Biotechnology industry median EV-to-EBITDA is 12.05. Clinuvel Pharmaceuticals' value of 4.77 is 60.4% below this industry median. Based on the distribution chart, Clinuvel Pharmaceuticals ranks #145 out of 411 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Clinuvel Pharmaceuticals has a GF Score™ of 87/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Clinuvel Pharmaceuticals' EV-to-EBITDA compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Clinuvel Pharmaceuticals ranks #145 out of 411 companies for EV-to-EBITDA. This puts Clinuvel Pharmaceuticals in the upper half of its industry. The industry median EV-to-EBITDA is 12.05. Clinuvel Pharmaceuticals' value of 4.77 is 60.4% below this benchmark. While the company's 10-year median is 27.33 vs. the industry median of 12.05, Clinuvel Pharmaceuticals has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 12.05, based on 411 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Clinuvel Pharmaceuticals's current EV-to-EBITDA of 4.77 is 60.4% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Clinuvel Pharmaceuticals. For the Biotechnology industry, the median EV-to-EBITDA is 12.05 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Clinuvel Pharmaceuticals's current EV-to-EBITDA is 4.77, which is 83% below median its own 10-year median of 27.33. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Clinuvel Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Clinuvel Pharmaceuticals (CLVLF) is currently considered Significantly Undervalued. The stock's GF Value™ is $12.49, compared to a current price of $6.37 — trading 49% below its estimated fair value. The current EV-to-EBITDA is 4.77, which is 83% below median its 10-year median of 27.33 and 60.4% below the Biotechnology industry median of 12.05. Clinuvel Pharmaceuticals' overall GF Score™ is 87/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Clinuvel Pharmaceuticals (CLVLF), the current EV-to-EBITDA is 4.77 as of Aug. 02, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Clinuvel Pharmaceuticals (CLVLF) Overvalued in 2026?
Based on GuruFocus' analysis, Clinuvel Pharmaceuticals stock appears to be undervalued.
The current stock price of $6.37 is trading 49% below its estimated GF Value™ of $12.49.
GuruFocus considers Clinuvel Pharmaceuticals to be Significantly Undervalued.
Key valuation signals for CLVLF:
EV-to-EBITDA: 4.77 (83% below median its 10-year median of 27.33)
GF Value™: $12.49 vs. price of $6.37 (49% below fair value)
Industry Position: 60.4% below the Biotechnology median (#145 of 411)
No single metric tells the full story. See the CLVLF stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Clinuvel distributes a single product, Scenesse, the only approved treatment for phototoxic reactions specifically associated with a rare genetic disease called erythropoietic protoporphyria. EPP causes extreme pain or burns from brief exposure to light, affecting a patient's quality of life. Scenesse is a patented dissolvable implant, comparable in size with a rice grain, injected underneath the skin roughly every three months for ongoing protection. The implant controls the release of a synthetic drug which promotes the production of more melanin, thereby reducing pain and increasing tolerance for light exposure. The majority of Clinuvel's earnings stem from Europe and the US.
87GF Score
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