EFTR (eFFECTOR Therapeutics) EV-to-EBITDA: 0.16 (As of Aug. 19, 2026)

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What is eFFECTOR Therapeutics EV-to-EBITDA?

eFFECTOR Therapeutics EFTR EV-to-EBITDA is 0.16 as of Aug. 19, 2026.

EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, eFFECTOR Therapeutics's enterprise value is $-5.13 Mil. eFFECTOR Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Mar. 2024 was $-31.54 Mil. Therefore, eFFECTOR Therapeutics's EV-to-EBITDA for today is 0.16.

The historical rank and industry rank for eFFECTOR Therapeutics's EV-to-EBITDA or its related term are showing as below:

EFTR' s EV-to-EBITDA Range Over the Past 10 Years
Min: 0   Med: 0   Max: 0.16
Current: 0.16

During the past 4 years, the highest EV-to-EBITDA of eFFECTOR Therapeutics was 0.16. The lowest was 0.00. And the median was 0.00.

EFTR's EV-to-EBITDA is not ranked
in the Biotechnology industry.
Industry Median: 13.6 vs EFTR: 0.16

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.

As of today (2026-08-19), eFFECTOR Therapeutics's stock price is $0.0008. eFFECTOR Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2024 was $-13.080. Therefore, eFFECTOR Therapeutics's PE Ratio (TTM) for today is At Loss.

The "classic" EV-to-EBITDA is much better in capturing debt and net cash than the PE Ratio (TTM).


eFFECTOR Therapeutics  (OTCPK:EFTR) EV-to-EBITDA Explanation

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

eFFECTOR Therapeutics's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=0.0008/-13.080
=At Loss

eFFECTOR Therapeutics's share price for today is $0.0008.
eFFECTOR Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2024 adds up the quarterly data reported by the company within the most recent 12 months, which was $-13.080.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).

Please read Which price ratio outperforms the enterprise multiple?


eFFECTOR Therapeutics EV-to-EBITDA Related Terms


eFFECTOR Therapeutics EV-to-EBITDA Historical Data

* Premium members only.

The historical data trend for eFFECTOR Therapeutics's EV-to-EBITDA can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

eFFECTOR Therapeutics EV-to-EBITDA Chart

eFFECTOR Therapeutics Annual Data
Trend Dec20 Dec21 Dec22 Dec23
EV-to-EBITDA
0.00 17.33 -0.58 -1.13

eFFECTOR Therapeutics Quarterly Data
Sep20 Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24
EV-to-EBITDA Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -0.49 -1.35 -1.22 -1.13 -1.62

EFTR vs NTBLQ, MTEM, VRTX: EV-to-EBITDA Comparison

For the Biotechnology subindustry, eFFECTOR Therapeutics's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


eFFECTOR Therapeutics EV-to-EBITDA vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, eFFECTOR Therapeutics's EV-to-EBITDA distribution charts can be found below:

* The bar in red indicates where eFFECTOR Therapeutics's EV-to-EBITDA falls into.



eFFECTOR Therapeutics EV-to-EBITDA Calculation

eFFECTOR Therapeutics's EV-to-EBITDA for today is calculated as:

EV-to-EBITDA=Enterprise Value (Today)/EBITDA (TTM)
=-5.132/-31.541
=0.16

eFFECTOR Therapeutics's current Enterprise Value is $-5.13 Mil.
eFFECTOR Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Mar. 2024 adds up the quarterly data reported by the company within the most recent 12 months, which was $-31.54 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBITDA →
What does a EV-to-EBITDA of 0.16 mean?
eFFECTOR Therapeutics (EFTR) has a EV-to-EBITDA of 0.16 as of Aug. 19, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on eFFECTOR Therapeutics.
Is eFFECTOR Therapeutics' EV-to-EBITDA too high?
eFFECTOR Therapeutics' current EV-to-EBITDA is 0.16. The Biotechnology industry median EV-to-EBITDA is 13.60. eFFECTOR Therapeutics' value of 0.16 is 98.8% below this industry median.
How does eFFECTOR Therapeutics' EV-to-EBITDA compare to NTBLQ and MTEM?
eFFECTOR Therapeutics' EV-to-EBITDA of 0.16 can be compared against companies in the Biotechnology industry. The industry median EV-to-EBITDA is 13.60. eFFECTOR Therapeutics' value of 0.16 is 98.8% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 13.60, based on 401 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. eFFECTOR Therapeutics's current EV-to-EBITDA of 0.16 is 98.8% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on eFFECTOR Therapeutics. For the Biotechnology industry, the median EV-to-EBITDA is 13.60 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. eFFECTOR Therapeutics's current EV-to-EBITDA is 0.16. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is eFFECTOR Therapeutics stock overvalued right now?
eFFECTOR Therapeutics (EFTR) has a current EV-to-EBITDA of 0.16. The current EV-to-EBITDA is 0.16 and 98.8% below the Biotechnology industry median of 13.60. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For eFFECTOR Therapeutics (EFTR), the current EV-to-EBITDA is 0.16 as of Aug. 19, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

eFFECTOR Therapeutics Business Description

Address 142 North Cedros Avenue, Suite B, Solana Beach, CA, USA, 92075
eFFECTOR Therapeutics Inc is a clinical-stage biopharmaceutical company focused on pioneering the development of a new class of oncology drugs referred to as selective translation regulator inhibitors (STRIs).