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EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Shanghai Henlius Biotech's enterprise value is €4,417.2 Mil.
Shanghai Henlius Biotech's EBITDA for the trailing twelve months (TTM) ended in Dec. 2025 was €162.6 Mil. Therefore, Shanghai Henlius Biotech's EV-to-EBITDA for today is 27.17.
The historical rank and industry rank for Shanghai Henlius Biotech's EV-to-EBITDA or its related term are showing as below:
FRA:2E8'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -57.27 Med: -15.57 Max: 33.81
Current: 27.08
During the past 9 years, the highest EV-to-EBITDA of Shanghai Henlius Biotech was 33.81. The lowest was -57.27. And the median was -15.57.
FRA:2E8's EV-to-EBITDA is ranked worse than 69.15% of 402
companies
in the Biotechnology industry
Industry Median: 13.825
vs FRA:2E8: 27.08
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Shanghai Henlius Biotech's PE Ratio (TTM) for today is calculated as:
Shanghai Henlius Biotech's share price for today is €7.30.
For company reported semi-annually, GuruFocus uses latest annual data as the TTM data. Shanghai Henlius Biotech's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Dec. 2025 was €0.183.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
FRA:2E8 vs VRTX, REGN, RVMD: EV-to-EBITDA Comparison
For the Biotechnology subindustry, Shanghai Henlius Biotech's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Shanghai Henlius Biotech EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Shanghai Henlius Biotech's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Shanghai Henlius Biotech's EV-to-EBITDA falls into.
Shanghai Henlius Biotech's current Enterprise Value is €4,417.2 Mil.
For company reported semi-annually, GuruFocus uses latest annual data as the TTM data. Shanghai Henlius Biotech's EBITDA for the trailing twelve months (TTM) ended in Dec. 2025 was €162.6 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Shanghai Henlius Biotech (FRA:2E8) has a EV-to-EBITDA of 27.17 as of Aug. 16, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Shanghai Henlius Biotech. According to the industry distribution chart, Shanghai Henlius Biotech ranks #278 out of 402 companies in the Biotechnology industry, placing it in the top 69.2%.
Is Shanghai Henlius Biotech's EV-to-EBITDA too high?
Shanghai Henlius Biotech's current EV-to-EBITDA is 27.17. The Biotechnology industry median EV-to-EBITDA is 13.83. Shanghai Henlius Biotech's value of 27.17 is 96.5% above this industry median. Based on the distribution chart, Shanghai Henlius Biotech ranks #278 out of 402 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Shanghai Henlius Biotech has a GF Score™ of 50/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Shanghai Henlius Biotech's EV-to-EBITDA compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Shanghai Henlius Biotech ranks #278 out of 402 companies for EV-to-EBITDA. This places Shanghai Henlius Biotech in the lower half of its industry. The industry median EV-to-EBITDA is 13.83. Shanghai Henlius Biotech's value of 27.17 is 96.5% above this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 13.83, based on 402 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Shanghai Henlius Biotech's current EV-to-EBITDA of 27.17 is 96.5% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Shanghai Henlius Biotech. For the Biotechnology industry, the median EV-to-EBITDA is 13.83 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Shanghai Henlius Biotech's current EV-to-EBITDA is 27.17. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Shanghai Henlius Biotech stock overvalued right now?
Based on GuruFocus' analysis, Shanghai Henlius Biotech (FRA:2E8) is currently considered Significantly Overvalued. The stock's GF Value™ is €3.38, compared to a current price of €7.30 — trading 116% above its estimated fair value. The current EV-to-EBITDA is 27.17 and 96.5% above the Biotechnology industry median of 13.83. Shanghai Henlius Biotech's overall GF Score™ is 50/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Shanghai Henlius Biotech (FRA:2E8), the current EV-to-EBITDA is 27.17 as of Aug. 16, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Shanghai Henlius Biotech (FRA:2E8) Overvalued in 2026?
Based on GuruFocus' analysis, Shanghai Henlius Biotech stock appears to be overvalued.
The current stock price of €7.30 is trading 116% above its estimated GF Value™ of €3.38.
GuruFocus considers Shanghai Henlius Biotech to be Significantly Overvalued.
Key valuation signals for FRA:2E8:
EV-to-EBITDA: 27.17
GF Value™: €3.38 vs. price of €7.30 (116% above fair value)
Industry Position: 96.5% above the Biotechnology median (#278 of 402)
No single metric tells the full story. See the FRA:2E8 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Shanghai Henlius Biotech Inc is a biopharmaceutical company in China with the vision to offer affordable and biologics for patients with a focus on oncology and autoimmune diseases. The Group is engaged in biopharmaceutical R&D, biopharmaceutical services, and biopharmaceutical production and sales. It operates in Mainland China, Asia Pacific (excluding Mainland China), North America, South America, Oceania, and Europe. The company products include HLX01 Rituximab, HLX02(trastuzumab), and others.
50GF Score
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