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Helix BioPharmaHBPCF 28 EV-to-EBITDA is -30.90 as of Jul. 16, 2026. GuruFocus rates HBPCF with a GF Score™ of 28/100. Among 395 Biotechnology companies, Helix BioPharma ranks worse than 253164.3% on this metric.
EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Helix BioPharma's enterprise value is $73.57 Mil.
Helix BioPharma's EBITDA for the trailing twelve months (TTM) ended in Apr. 2026 was $-2.38 Mil. Therefore, Helix BioPharma's EV-to-EBITDA for today is -30.90.
The historical rank and industry rank for Helix BioPharma's EV-to-EBITDA or its related term are showing as below:
HBPCF'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -32.58 Med: 0 Max: 0
Current: -32.58
HBPCF's EV-to-EBITDA is ranked worse than 100% of 395
companies
in the Biotechnology industry
Industry Median: 13
vs HBPCF: -32.58
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Helix BioPharma's PE Ratio (TTM) for today is calculated as:
Helix BioPharma's share price for today is $1.71.
Helix BioPharma's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Apr. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-0.028.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
The historical data trend for Helix BioPharma's EV-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
HBPCF vs VRTX, REGN, ALNY: EV-to-EBITDA Comparison
For the Biotechnology subindustry, Helix BioPharma's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Helix BioPharma EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Helix BioPharma's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Helix BioPharma's EV-to-EBITDA falls into.
Helix BioPharma's current Enterprise Value is $73.57 Mil.
Helix BioPharma's EBITDA for the trailing twelve months (TTM) ended in Apr. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-2.38 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Helix BioPharma (HBPCF) has a EV-to-EBITDA of -30.90 as of Jul. 16, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Helix BioPharma. According to the industry distribution chart, Helix BioPharma ranks #999999 out of 395 companies in the Biotechnology industry.
Is Helix BioPharma's EV-to-EBITDA too high?
Helix BioPharma's current EV-to-EBITDA is -30.90. Based on the distribution chart, Helix BioPharma ranks #999999 out of 395 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Helix BioPharma has a GF Score™ of 28/100, reflecting its overall financial health beyond just this single metric.
How does Helix BioPharma's EV-to-EBITDA compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Helix BioPharma ranks #999999 out of 395 companies for EV-to-EBITDA. This places Helix BioPharma in the lower half of its industry. The industry median EV-to-EBITDA is 13.00. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 13.00, based on 395 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Helix BioPharma. For the Biotechnology industry, the median EV-to-EBITDA is 13.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Helix BioPharma's current EV-to-EBITDA is -30.90. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Helix BioPharma stock overvalued right now?
Helix BioPharma (HBPCF) has a current EV-to-EBITDA of -30.90. The current EV-to-EBITDA is -30.90. Helix BioPharma's overall GF Score™ is 28/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Helix BioPharma (HBPCF), the current EV-to-EBITDA is -30.90 as of Jul. 16, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Helix BioPharma Corp is a clinical-stage biopharmaceutical company developing therapies in immune-oncology focused on cancer prevention and treatment. The Company is developing a proprietary platform of bio-conjugates targeting hard-to-treat solid tumors over-expressing CEACAM6, including Tumor Defense Breaker, L-DOS47, and three CEACAM6-specific antibody-drug conjugates. Its pre-IND candidates include LEUMUNA, an oral immune checkpoint modulator for hematological malignancies, and GEMCEDA, an oral prodrug of gemcitabine for solid tumors.
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