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Monopar TherapeuticsMNPR +4.32%34 EV-to-EBITDA is -32.00 as of Jul. 26, 2026. GuruFocus rates MNPR with a GF Score™ of 34/100. The stock has 3 warning signs investors should review. Among 404 Biotechnology companies, Monopar Therapeutics ranks worse than 247524.5% on this metric.
EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Monopar Therapeutics's enterprise value is $598.67 Mil.
Monopar Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was $-18.71 Mil. Therefore, Monopar Therapeutics's EV-to-EBITDA for today is -32.00.
The historical rank and industry rank for Monopar Therapeutics's EV-to-EBITDA or its related term are showing as below:
MNPR'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -32 Med: 0 Max: 0
Current: -32
MNPR's EV-to-EBITDA is ranked worse than 100% of 404
companies
in the Biotechnology industry
Industry Median: 11.82
vs MNPR: -32.00
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Monopar Therapeutics's PE Ratio (TTM) for today is calculated as:
Monopar Therapeutics's share price for today is $109.87.
Monopar Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-1.930.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
The historical data trend for Monopar Therapeutics's EV-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Monopar Therapeutics's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Monopar Therapeutics EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Monopar Therapeutics's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Monopar Therapeutics's EV-to-EBITDA falls into.
Monopar Therapeutics's current Enterprise Value is $598.67 Mil.
Monopar Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-18.71 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Monopar Therapeutics (MNPR) has a EV-to-EBITDA of -32.00 as of Jul. 26, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Monopar Therapeutics. According to the industry distribution chart, Monopar Therapeutics ranks #999999 out of 404 companies in the Biotechnology industry.
Is Monopar Therapeutics' EV-to-EBITDA too high?
Monopar Therapeutics' current EV-to-EBITDA is -32.00. Based on the distribution chart, Monopar Therapeutics ranks #999999 out of 404 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Monopar Therapeutics has a GF Score™ of 34/100, reflecting its overall financial health beyond just this single metric.
How does Monopar Therapeutics' EV-to-EBITDA compare to MDXG and FTH?
According to the Biotechnology industry distribution chart, Monopar Therapeutics ranks #999999 out of 404 companies for EV-to-EBITDA. This places Monopar Therapeutics in the lower half of its industry. The industry median EV-to-EBITDA is 11.82. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 11.82, based on 404 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Monopar Therapeutics. For the Biotechnology industry, the median EV-to-EBITDA is 11.82 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Monopar Therapeutics's current EV-to-EBITDA is -32.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Monopar Therapeutics stock overvalued right now?
Monopar Therapeutics (MNPR) has a current EV-to-EBITDA of -32.00. The current EV-to-EBITDA is -32.00. Monopar Therapeutics' overall GF Score™ is 34/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Monopar Therapeutics (MNPR), the current EV-to-EBITDA is -32.00 as of Jul. 26, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Monopar Therapeutics Inc is a clinical-stage biopharmaceutical company developing a treatment for Wilson disease and novel radiopharmaceuticals for oncology. Its Wilson disease product candidate is ALXN1840, a late-stage, investigational once-daily, oral medicine. The group radiopharmaceutical programs consist of Phase 1-stage MNPR-101-Zr for imaging cancers, and Phase 1a-stage MNPR-101-Lu and late preclinical-stage MNPR-101-Ac for the treatment of cancers that express urokinase plasminogen activator receptor (uPAR). It build drug development pipeline through both in-house efforts and licensing of late preclinical- and clinical-stage therapeutics. The Company operates as a single reportable segment, focusing on the development of clinical and preclinical product candidates.
34GF Score
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