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EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Sarepta Therapeutics's enterprise value is $2,242 Mil.
Sarepta Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 was $-15 Mil. Therefore, Sarepta Therapeutics's EV-to-EBITDA for today is -153.74.
The historical rank and industry rank for Sarepta Therapeutics's EV-to-EBITDA or its related term are showing as below:
SRPT'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -157.03 Med: -14.77 Max: 166.25
Current: -153.74
During the past 13 years, the highest EV-to-EBITDA of Sarepta Therapeutics was 166.25. The lowest was -157.03. And the median was -14.77.
SRPT's EV-to-EBITDA is ranked worse than 100% of 407
companies
in the Biotechnology industry
Industry Median: 14.17
vs SRPT: -153.74
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Sarepta Therapeutics's PE Ratio (TTM) for today is calculated as:
Sarepta Therapeutics's share price for today is $18.79.
Sarepta Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-2.900.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
The historical data trend for Sarepta Therapeutics's EV-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Sarepta Therapeutics's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Sarepta Therapeutics EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Sarepta Therapeutics's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where Sarepta Therapeutics's EV-to-EBITDA falls into.
Sarepta Therapeutics's current Enterprise Value is $2,242 Mil.
Sarepta Therapeutics's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-15 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Sarepta Therapeutics (SRPT) has a EV-to-EBITDA of -153.74 as of Aug. 23, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Sarepta Therapeutics. According to the industry distribution chart, Sarepta Therapeutics ranks #999999 out of 407 companies in the Biotechnology industry.
Is Sarepta Therapeutics' EV-to-EBITDA too high?
Sarepta Therapeutics' current EV-to-EBITDA is -153.74. Based on the distribution chart, Sarepta Therapeutics ranks #999999 out of 407 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Sarepta Therapeutics has a GF Score™ of 53/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Sarepta Therapeutics' EV-to-EBITDA compare to MPLT and ZYME?
According to the Biotechnology industry distribution chart, Sarepta Therapeutics ranks #999999 out of 407 companies for EV-to-EBITDA. This places Sarepta Therapeutics in the lower half of its industry. The industry median EV-to-EBITDA is 14.17. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 14.17, based on 407 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Sarepta Therapeutics. For the Biotechnology industry, the median EV-to-EBITDA is 14.17 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Sarepta Therapeutics's current EV-to-EBITDA is -153.74. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Sarepta Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Sarepta Therapeutics (SRPT) is currently considered Possible Value Trap. The stock's GF Value™ is $109.23, compared to a current price of $18.79 — trading 82.8% below its estimated fair value. The current EV-to-EBITDA is -153.74. Sarepta Therapeutics' overall GF Score™ is 53/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Sarepta Therapeutics (SRPT), the current EV-to-EBITDA is -153.74 as of Aug. 23, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Sarepta Therapeutics (SRPT) Overvalued in 2026?
Based on GuruFocus' analysis, Sarepta Therapeutics stock appears to be undervalued.
The current stock price of $18.79 is trading 82.8% below its estimated GF Value™ of $109.23.
GuruFocus considers Sarepta Therapeutics to be Possible Value Trap.
Key valuation signals for SRPT:
EV-to-EBITDA: -153.74
GF Value™: $109.23 vs. price of $18.79 (82.8% below fair value)
No single metric tells the full story. See the SRPT stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Sarepta Therapeutics Inc is a commercial-stage biopharmaceutical company focused on the discovery and development of RNA-targeted therapies, gene therapies, and other genetic medicines for rare diseases, particularly neuromuscular disorders. The company has developed approved treatments for Duchenne muscular dystrophy, including EXONDYS 51, VYONDYS 53, AMONDYS 45, and ELEVIDYS, and is advancing additional therapeutic candidates for neuromuscular and other rare diseases. The company operates in one segment: discovering, developing, manufacturing, and delivering therapies to patients with rare diseases.
53GF Score
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