TNXP (Tonix Pharmaceuticals Holding) EV-to-EBITDA: -0.25 (As of Aug. 23, 2026)

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TNXP Tonix Pharmaceuticals Holding Corp TNXP
41 GF Score
Price $12.54
GF Value $3.11
Valuation Significantly Overvalued
! 2 Warning Signs
View Full Analysis

What is Tonix Pharmaceuticals Holding EV-to-EBITDA?

Tonix Pharmaceuticals Holding TNXP +1.46% 41 EV-to-EBITDA is -0.25 as of Aug. 23, 2026. GuruFocus rates TNXP with a GF Score™ of 41/100 and a GF Value™ of $3.11 (Significantly Overvalued). The stock has 2 warning signs investors should review. Among 407 Biotechnology companies, Tonix Pharmaceuticals Holding ranks worse than 245700% on this metric.

EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, Tonix Pharmaceuticals Holding's enterprise value is $40.11 Mil. Tonix Pharmaceuticals Holding's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 was $-160.27 Mil. Therefore, Tonix Pharmaceuticals Holding's EV-to-EBITDA for today is -0.25.

The historical rank and industry rank for Tonix Pharmaceuticals Holding's EV-to-EBITDA or its related term are showing as below:

TNXP' s EV-to-EBITDA Range Over the Past 10 Years
Min: -3.3   Med: -0.04   Max: 0.78
Current: -0.25

During the past 13 years, the highest EV-to-EBITDA of Tonix Pharmaceuticals Holding was 0.78. The lowest was -3.30. And the median was -0.04.

TNXP's EV-to-EBITDA is ranked worse than
100% of 407 companies
in the Biotechnology industry
Industry Median: 14.17 vs TNXP: -0.25

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.

As of today (2026-08-23), Tonix Pharmaceuticals Holding's stock price is $12.54. Tonix Pharmaceuticals Holding's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 was $-12.940. Therefore, Tonix Pharmaceuticals Holding's PE Ratio (TTM) for today is At Loss.

The "classic" EV-to-EBITDA is much better in capturing debt and net cash than the PE Ratio (TTM).


Tonix Pharmaceuticals Holding  (NAS:TNXP) EV-to-EBITDA Explanation

EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Tonix Pharmaceuticals Holding's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=12.54/-12.940
=At Loss

Tonix Pharmaceuticals Holding's share price for today is $12.54.
Tonix Pharmaceuticals Holding's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-12.940.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).

Please read Which price ratio outperforms the enterprise multiple?


Tonix Pharmaceuticals Holding EV-to-EBITDA Related Terms


Tonix Pharmaceuticals Holding EV-to-EBITDA Historical Data

* Premium members only.

The historical data trend for Tonix Pharmaceuticals Holding's EV-to-EBITDA can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Tonix Pharmaceuticals Holding EV-to-EBITDA Chart

Tonix Pharmaceuticals Holding Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-EBITDA
Get a 7-Day Free Trial Premium Member Only Premium Member Only -0.56 0.80 -0.07 -0.43 0.05

Tonix Pharmaceuticals Holding Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
EV-to-EBITDA Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -1.93 -0.59 0.05 -0.08 -0.25

TNXP vs EQ, ARCT, SMNR: EV-to-EBITDA Comparison

For the Biotechnology subindustry, Tonix Pharmaceuticals Holding's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Tonix Pharmaceuticals Holding EV-to-EBITDA vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Tonix Pharmaceuticals Holding's EV-to-EBITDA distribution charts can be found below:

* The bar in red indicates where Tonix Pharmaceuticals Holding's EV-to-EBITDA falls into.


TNXP
41GF Score
Tonix Pharmaceuticals Holding Corp TNXP
EV-to-EBITDA is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Tonix Pharmaceuticals Holding EV-to-EBITDA Calculation

Tonix Pharmaceuticals Holding's EV-to-EBITDA for today is calculated as:

EV-to-EBITDA=Enterprise Value (Today)/EBITDA (TTM)
=40.114/-160.269
=-0.25

Tonix Pharmaceuticals Holding's current Enterprise Value is $40.11 Mil.
Tonix Pharmaceuticals Holding's EBITDA for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-160.27 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-EBITDA →
What does a EV-to-EBITDA of -0.25 mean?
Tonix Pharmaceuticals Holding (TNXP) has a EV-to-EBITDA of -0.25 as of Aug. 23, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Tonix Pharmaceuticals Holding. According to the industry distribution chart, Tonix Pharmaceuticals Holding ranks #999999 out of 407 companies in the Biotechnology industry.
Is Tonix Pharmaceuticals Holding's EV-to-EBITDA too high?
Tonix Pharmaceuticals Holding's current EV-to-EBITDA is -0.25. Based on the distribution chart, Tonix Pharmaceuticals Holding ranks #999999 out of 407 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Tonix Pharmaceuticals Holding has a GF Score™ of 41/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Tonix Pharmaceuticals Holding's EV-to-EBITDA compare to EQ and ARCT?
According to the Biotechnology industry distribution chart, Tonix Pharmaceuticals Holding ranks #999999 out of 407 companies for EV-to-EBITDA. This places Tonix Pharmaceuticals Holding in the lower half of its industry. The industry median EV-to-EBITDA is 14.17. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 14.17, based on 407 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on Tonix Pharmaceuticals Holding. For the Biotechnology industry, the median EV-to-EBITDA is 14.17 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Tonix Pharmaceuticals Holding's current EV-to-EBITDA is -0.25. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Tonix Pharmaceuticals Holding stock overvalued right now?
Based on GuruFocus' analysis, Tonix Pharmaceuticals Holding (TNXP) is currently considered Significantly Overvalued. The stock's GF Value™ is $3.11, compared to a current price of $12.54 — trading 303.2% above its estimated fair value. The current EV-to-EBITDA is -0.25. Tonix Pharmaceuticals Holding's overall GF Score™ is 41/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For Tonix Pharmaceuticals Holding (TNXP), the current EV-to-EBITDA is -0.25 as of Aug. 23, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Tonix Pharmaceuticals Holding (TNXP) Overvalued in 2026?

Based on GuruFocus' analysis, Tonix Pharmaceuticals Holding stock appears to be overvalued. The current stock price of $12.54 is trading 303.2% above its estimated GF Value™ of $3.11. GuruFocus considers Tonix Pharmaceuticals Holding to be Significantly Overvalued.

Key valuation signals for TNXP:

  • EV-to-EBITDA: -0.25
  • GF Value™: $3.11 vs. price of $12.54 (303.2% above fair value)
  • GF Score™: 41/100 with 2 warning signs

No single metric tells the full story. See the TNXP stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Tonix Pharmaceuticals Holding Business Description

Other Exchanges TPM0:Germany
Address 200 Connell Drive, Suite 3100, Berkeley Heights, NJ, USA, 07928
Tonix Pharmaceuticals Holding Corp is a fully-integrated biopharmaceutical company commercializing and developing therapies for central nervous system (CNS) disorders, immunology, infectious diseases, and rare diseases. Its portfolio consists of commercial, development and discovery-stage programs, TONMYA, an approved treatment for fibromyalgia, as well as marketed acute migraine products Zembrace SymTouch and Tosymra. The company is conducting clinical trials to evaluate TONMYA for additional indications such as depressive disorder and acute stress disorder. It is also advancing a pipeline of immunology programs, including monoclonal antibody TNX-4800 for Lyme disease prophylaxis and TNX-1500, a third-generation CD40 ligand inhibitor for the prevention of kidney transplant rejection.
41GF Score

Get the complete analysis for TNXP

EV-to-EBITDA is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$12.54
Price
$3.11
GF Value