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StemRIMTSE:4599 -0.84%32 EV-to-EBITDA is -7.46 as of Aug. 24, 2026. GuruFocus rates TSE:4599 with a GF Score™ of 32/100. The stock has 3 warning signs investors should review. Among 408 Biotechnology companies, StemRIM ranks worse than 245097.79% on this metric.
EV-to-EBITDA is calculated as enterprise value divided by its EBITDA. As of today, StemRIM's enterprise value is 円13,966.70 Mil.
StemRIM's EBITDA for the trailing twelve months (TTM) ended in Jan. 2026 was 円-1,871.40 Mil. Therefore, StemRIM's EV-to-EBITDA for today is -7.46.
The historical rank and industry rank for StemRIM's EV-to-EBITDA or its related term are showing as below:
TSE:4599'
s EV-to-EBITDA Range Over the Past 10 Years
Min: -80.22 Med: 52.25 Max: 360.27
Current: -7.46
During the past 9 years, the highest EV-to-EBITDA of StemRIM was 360.27. The lowest was -80.22. And the median was 52.25.
TSE:4599's EV-to-EBITDA is ranked worse than 100% of 408
companies
in the Biotechnology industry
Industry Median: 14.13
vs TSE:4599: -7.46
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio to determine the fair market value of a company.
As of today (2026-08-24), StemRIM's stock price is 円354.00.
StemRIM's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jan. 2026 was 円-29.968. Therefore, StemRIM's PE Ratio (TTM) for today is At Loss.
The "classic" EV-to-EBITDA is much better in capturing debt and net cash than the PE Ratio (TTM).
EV-to-EBITDA is a valuation multiple used in finance and investment to measure the value of a company. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
StemRIM's share price for today is 円354.00.
StemRIM's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jan. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was 円-29.968.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Study has found that the companies with the lowest EV-to-EBITDA outperforms companies measured as cheap by other ratios such as PE Ratio (TTM).
The historical data trend for StemRIM's EV-to-EBITDA can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
TSE:4599 vs VRTX, REGN, RVMD: EV-to-EBITDA Comparison
For the Biotechnology subindustry, StemRIM's EV-to-EBITDA, along with its competitors' market caps and EV-to-EBITDA data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
StemRIM EV-to-EBITDA vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, StemRIM's EV-to-EBITDA distribution charts can be found below:
* The bar in red indicates where StemRIM's EV-to-EBITDA falls into.
StemRIM's current Enterprise Value is 円13,966.70 Mil.
StemRIM's EBITDA for the trailing twelve months (TTM) ended in Jan. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was 円-1,871.40 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
StemRIM (TSE:4599) has a EV-to-EBITDA of -7.46 as of Aug. 24, 2026. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on StemRIM. According to the industry distribution chart, StemRIM ranks #999999 out of 408 companies in the Biotechnology industry.
Is StemRIM's EV-to-EBITDA too high?
StemRIM's current EV-to-EBITDA is -7.46. Based on the distribution chart, StemRIM ranks #999999 out of 408 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, StemRIM has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does StemRIM's EV-to-EBITDA compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, StemRIM ranks #999999 out of 408 companies for EV-to-EBITDA. This places StemRIM in the lower half of its industry. The industry median EV-to-EBITDA is 14.13. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-EBITDA for a Biotechnology company?
The median EV-to-EBITDA among Biotechnology companies is 14.13, based on 408 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-EBITDA significantly above this median, while those in the bottom quartile fall well below. However, EV-to-EBITDA should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-EBITDA mean?
A high EV-to-EBITDA can signal that a stock is expensive relative to its fundamentals. EV to EBITDA ratio is the company's enterprise value divided by earnings before interest, taxes, depreciation and amortization. View historical data on StemRIM. For the Biotechnology industry, the median EV-to-EBITDA is 14.13 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. StemRIM's current EV-to-EBITDA is -7.46. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is StemRIM stock overvalued right now?
StemRIM (TSE:4599) has a current EV-to-EBITDA of -7.46. The current EV-to-EBITDA is -7.46. StemRIM's overall GF Score™ is 32/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-EBITDA calculated?
EV-to-EBITDA is calculated from a company's financial statements. For StemRIM (TSE:4599), the current EV-to-EBITDA is -7.46 as of Aug. 24, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
StemRIM Inc is a biotechnology company engaged in developing regeneration-guided medicines. The business activity of the group includes research, development, manufacture, and sales of pharmaceuticals and medical devices and products such as gene therapy that activate stem cells existing in the body and induce regeneration of damaged tissue.
32GF Score
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