BCYC (Bicycle Therapeutics) EV-to-OCF: 0.93 (As of Aug. 27, 2026)

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BCYC Bicycle Therapeutics PLC BCYC
56 GF Score
Price $4.35
GF Value $13.15
Valuation Possible Value Trap
! 5 Warning Signs
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What is Bicycle Therapeutics EV-to-OCF?

Bicycle Therapeutics BCYC -0.80% 56 EV-to-OCF is 0.93 as of Aug. 27, 2026. GuruFocus rates BCYC with a GF Score™ of 56/100 and a GF Value™ of $13.15 (Possible Value Trap). The stock has 5 warning signs investors should review. Among 1,409 Biotechnology companies, Bicycle Therapeutics ranks worse than 77.71% on this metric.

EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, Bicycle Therapeutics's Enterprise Value is $-190.92 Mil. Bicycle Therapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 was $-206.05 Mil. Therefore, Bicycle Therapeutics's EV-to-OCF for today is 0.93.

The historical rank and industry rank for Bicycle Therapeutics's EV-to-OCF or its related term are showing as below:

BCYC' s EV-to-OCF Range Over the Past 10 Years
Min: -94.97   Med: -5.06   Max: 2.16
Current: 0.93

During the past 9 years, the highest EV-to-OCF of Bicycle Therapeutics was 2.16. The lowest was -94.97. And the median was -5.06.

BCYC's EV-to-OCF is ranked worse than
77.71% of 1409 companies
in the Biotechnology industry
Industry Median: -3.71 vs BCYC: 0.93

EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

As of today (2026-08-27), Bicycle Therapeutics's stock price is $4.35. Bicycle Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 was $-2.730. Therefore, Bicycle Therapeutics's PE Ratio (TTM) for today is At Loss.


Bicycle Therapeutics  (NAS:BCYC) EV-to-OCF Explanation

EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Bicycle Therapeutics's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=4.35/-2.730
=At Loss

Bicycle Therapeutics's share price for today is $4.35.
Bicycle Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-2.730.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.


Bicycle Therapeutics EV-to-OCF Related Terms


Bicycle Therapeutics EV-to-OCF Historical Data

* Premium members only.

The historical data trend for Bicycle Therapeutics's EV-to-OCF can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Bicycle Therapeutics EV-to-OCF Chart

Bicycle Therapeutics Annual Data
Trend Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-OCF
Get a 7-Day Free Trial Premium Member Only -95.05 -6.85 -4.71 -0.59 0.48

Bicycle Therapeutics Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
EV-to-OCF Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 1.12 0.44 0.48 0.96 0.97

BCYC vs CYDY, ALXO, SABS: EV-to-OCF Comparison

For the Biotechnology subindustry, Bicycle Therapeutics's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Bicycle Therapeutics EV-to-OCF vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Bicycle Therapeutics's EV-to-OCF distribution charts can be found below:

* The bar in red indicates where Bicycle Therapeutics's EV-to-OCF falls into.


BCYC
56GF Score
Bicycle Therapeutics PLC BCYC
EV-to-OCF is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Bicycle Therapeutics EV-to-OCF Calculation

Bicycle Therapeutics's EV-to-OCF for today is calculated as:

EV-to-OCF=Enterprise Value (Today)/Cash Flow from Operations (TTM)
=-190.922/-206.05
=0.93

Bicycle Therapeutics's current Enterprise Value is $-190.92 Mil.
Bicycle Therapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-206.05 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-OCF →
What does a EV-to-OCF of 0.93 mean?
Bicycle Therapeutics (BCYC) has a EV-to-OCF of 0.93 as of Aug. 27, 2026. According to the industry distribution chart, Bicycle Therapeutics ranks #1095 out of 1409 companies in the Biotechnology industry, placing it in the top 77.7%.
Is Bicycle Therapeutics' EV-to-OCF too high?
Bicycle Therapeutics' current EV-to-OCF is 0.93. Based on the distribution chart, Bicycle Therapeutics ranks #1095 out of 1409 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Bicycle Therapeutics has a GF Score™ of 56/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Bicycle Therapeutics' EV-to-OCF compare to CYDY and ALXO?
According to the Biotechnology industry distribution chart, Bicycle Therapeutics ranks #1095 out of 1409 companies for EV-to-OCF. This places Bicycle Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Biotechnology company?
A good EV-to-OCF depends on the Biotechnology industry context. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. Bicycle Therapeutics's current EV-to-OCF is 0.93. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Bicycle Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Bicycle Therapeutics (BCYC) is currently considered Possible Value Trap. The stock's GF Value™ is $13.15, compared to a current price of $4.35 — trading 66.9% below its estimated fair value. The current EV-to-OCF is 0.93. Bicycle Therapeutics' overall GF Score™ is 56/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For Bicycle Therapeutics (BCYC), the current EV-to-OCF is 0.93 as of Aug. 27, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Bicycle Therapeutics (BCYC) Overvalued in 2026?

Based on GuruFocus' analysis, Bicycle Therapeutics stock appears to be undervalued. The current stock price of $4.35 is trading 66.9% below its estimated GF Value™ of $13.15. GuruFocus considers Bicycle Therapeutics to be Possible Value Trap.

Key valuation signals for BCYC:

  • EV-to-OCF: 0.93
  • GF Value™: $13.15 vs. price of $4.35 (66.9% below fair value)
  • GF Score™: 56/100 with 5 warning signs

No single metric tells the full story. See the BCYC stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Bicycle Therapeutics Business Description

Other Exchanges 50BA:Germany
Address Granta Park, Great Abington, Blocks A and B, Portway Building, Cambridge, GBR, CB21 6GS
Bicycle Therapeutics PLC is a clinical-stage biopharmaceutical company developing a novel class of medicines which are referred to as Bicycles. The Bicycles are synthetic short peptides constrained to form two loops that stabilize their structural geometry. Its initial internal programs are focused on oncology indications with high unmet medical needs. The company's product candidate, BT1718, is a Bicycle Toxin Conjugate, or BTC. The company has two segments: the United Kingdom and the United States. It derives maximum revenue from United Kingdom.
56GF Score

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EV-to-OCF is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$4.35
Price
$13.15
GF Value