CDXS (Codexis) EV-to-OCF: -18.43 (As of Aug. 17, 2026)

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CDXS Codexis Inc CDXS
57 GF Score
Price $1.60
GF Value $2.57
Valuation Possible Value Trap
! 6 Warning Signs
View Full Analysis

What is Codexis EV-to-OCF?

Codexis CDXS +1.60% 57 EV-to-OCF is -18.43 as of Aug. 17, 2026. GuruFocus rates CDXS with a GF Score™ of 57/100 and a GF Value™ of $2.57 (Possible Value Trap). The stock has 6 warning signs investors should review. Among 1,410 Biotechnology companies, Codexis ranks better than 78.87% on this metric.

EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, Codexis's Enterprise Value is $191.79 Mil. Codexis's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 was $-10.40 Mil. Therefore, Codexis's EV-to-OCF for today is -18.43.

The historical rank and industry rank for Codexis's EV-to-OCF or its related term are showing as below:

CDXS' s EV-to-OCF Range Over the Past 10 Years
Min: -312.21   Med: -34.97   Max: 1519.34
Current: -18.43

During the past 13 years, the highest EV-to-OCF of Codexis was 1519.34. The lowest was -312.21. And the median was -34.97.

CDXS's EV-to-OCF is ranked better than
78.87% of 1410 companies
in the Biotechnology industry
Industry Median: -3.625 vs CDXS: -18.43

EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

As of today (2026-08-17), Codexis's stock price is $1.595. Codexis's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 was $-0.340. Therefore, Codexis's PE Ratio (TTM) for today is At Loss.


Codexis  (NAS:CDXS) EV-to-OCF Explanation

EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Codexis's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=1.595/-0.340
=At Loss

Codexis's share price for today is $1.595.
Codexis's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-0.340.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.


Codexis EV-to-OCF Related Terms


Codexis EV-to-OCF Historical Data

* Premium members only.

The historical data trend for Codexis's EV-to-OCF can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Codexis EV-to-OCF Chart

Codexis Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-OCF
Get a 7-Day Free Trial Premium Member Only Premium Member Only -137.86 20.94 -3.12 -7.63 -7.35

Codexis Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
EV-to-OCF Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -3.64 -4.12 -7.35 -8.33 -21.55

CDXS vs CUE, CNTB, HURA: EV-to-OCF Comparison

For the Biotechnology subindustry, Codexis's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Codexis EV-to-OCF vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Codexis's EV-to-OCF distribution charts can be found below:

* The bar in red indicates where Codexis's EV-to-OCF falls into.


CDXS
57GF Score
Codexis Inc CDXS
EV-to-OCF is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Codexis EV-to-OCF Calculation

Codexis's EV-to-OCF for today is calculated as:

EV-to-OCF=Enterprise Value (Today)/Cash Flow from Operations (TTM)
=191.785/-10.404
=-18.43

Codexis's current Enterprise Value is $191.79 Mil.
Codexis's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-10.40 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-OCF →
What does a EV-to-OCF of -18.43 mean?
Codexis (CDXS) has a EV-to-OCF of -18.43 as of Aug. 17, 2026. According to the industry distribution chart, Codexis ranks #298 out of 1410 companies in the Biotechnology industry, placing it in the top 21.1%.
Is Codexis' EV-to-OCF too high?
Codexis' current EV-to-OCF is -18.43. Based on the distribution chart, Codexis ranks #298 out of 1410 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Codexis has a GF Score™ of 57/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Codexis' EV-to-OCF compare to CUE and CNTB?
According to the Biotechnology industry distribution chart, Codexis ranks #298 out of 1410 companies for EV-to-OCF. This places Codexis in the top 21% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Biotechnology company?
A good EV-to-OCF depends on the Biotechnology industry context. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. Codexis's current EV-to-OCF is -18.43. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Codexis stock overvalued right now?
Based on GuruFocus' analysis, Codexis (CDXS) is currently considered Possible Value Trap. The stock's GF Value™ is $2.57, compared to a current price of $1.60 — trading 37.9% below its estimated fair value. The current EV-to-OCF is -18.43. Codexis' overall GF Score™ is 57/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For Codexis (CDXS), the current EV-to-OCF is -18.43 as of Aug. 17, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Codexis (CDXS) Overvalued in 2026?

Based on GuruFocus' analysis, Codexis stock appears to be undervalued. The current stock price of $1.60 is trading 37.9% below its estimated GF Value™ of $2.57. GuruFocus considers Codexis to be Possible Value Trap.

Key valuation signals for CDXS:

  • EV-to-OCF: -18.43
  • GF Value™: $2.57 vs. price of $1.60 (37.9% below fair value)
  • GF Score™: 57/100 with 6 warning signs

No single metric tells the full story. See the CDXS stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Codexis Business Description

Other Exchanges 0I0X:UK4QK:Germany
Address 200 Penobscot Drive, Redwood City, CA, USA, 94063
Codexis Inc is a biotechnology company engaged in providing enzyme-based technology solutions to improve pharmaceutical manufacturing processes. The company operates through two key business areas: the ECO Synthesis manufacturing platform and small molecule pharma biocatalysis. The ECO Synthesis platform focuses on developing enzymatic processes for the large-scale manufacture of RNA interference therapeutics, while the biocatalysis business utilizes engineered enzymes to enhance efficiency, yield, and sustainability in small molecule drug manufacturing. Geographically, it derives maximum revenue from the Americas.
57GF Score

Get the complete analysis for CDXS

EV-to-OCF is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$1.60
Price
$2.57
GF Value