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Defence TherapeuticsDTCFF 25 EV-to-OCF is -6.29 as of Aug. 11, 2026. GuruFocus rates DTCFF with a GF Score™ of 25/100. The stock has 1 warning sign investors should review. Among 1,406 Biotechnology companies, Defence Therapeutics ranks better than 61.02% on this metric.
EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, Defence Therapeutics's Enterprise Value is $20.73 Mil.
Defence Therapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 was $-3.30 Mil. Therefore, Defence Therapeutics's EV-to-OCF for today is -6.29.
The historical rank and industry rank for Defence Therapeutics's EV-to-OCF or its related term are showing as below:
DTCFF'
s EV-to-OCF Range Over the Past 10 Years
Min: -6.38 Med: 0 Max: -5.61
Current: -6.29
During the past 6 years, the highest EV-to-OCF of Defence Therapeutics was -5.61. The lowest was -6.38. And the median was .
DTCFF's EV-to-OCF is ranked better than 61.02% of 1406
companies
in the Biotechnology industry
Industry Median: -3.515
vs DTCFF: -6.29
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Defence Therapeutics's PE Ratio (TTM) for today is calculated as:
Defence Therapeutics's share price for today is $0.2694.
Defence Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-0.065.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.
Defence Therapeutics EV-to-OCF Related Terms
Defence Therapeutics EV-to-OCF Historical Data
* Premium members only.
The historical data trend for Defence Therapeutics's EV-to-OCF can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Defence Therapeutics's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Defence Therapeutics EV-to-OCF vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Defence Therapeutics's EV-to-OCF distribution charts can be found below:
* The bar in red indicates where Defence Therapeutics's EV-to-OCF falls into.
Defence Therapeutics's current Enterprise Value is $20.73 Mil.
Defence Therapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-3.30 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Defence Therapeutics (DTCFF) has a EV-to-OCF of -6.29 as of Aug. 11, 2026. According to the industry distribution chart, Defence Therapeutics ranks #548 out of 1406 companies in the Biotechnology industry, placing it in the top 39%.
Is Defence Therapeutics' EV-to-OCF too high?
Defence Therapeutics' current EV-to-OCF is -6.29. Based on the distribution chart, Defence Therapeutics ranks #548 out of 1406 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Defence Therapeutics has a GF Score™ of 25/100, reflecting its overall financial health beyond just this single metric.
How does Defence Therapeutics' EV-to-OCF compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Defence Therapeutics ranks #548 out of 1406 companies for EV-to-OCF. This puts Defence Therapeutics in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Biotechnology company?
A good EV-to-OCF depends on the Biotechnology industry context. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. Defence Therapeutics's current EV-to-OCF is -6.29. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Defence Therapeutics stock overvalued right now?
Defence Therapeutics (DTCFF) has a current EV-to-OCF of -6.29. The current EV-to-OCF is -6.29. Defence Therapeutics' overall GF Score™ is 25/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For Defence Therapeutics (DTCFF), the current EV-to-OCF is -6.29 as of Aug. 11, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Defence Therapeutics Inc is engaged in the development of a biological drug enhancer platform that improves the efficacy and safety of a multitude of biological/biosimilar-based pharmaceuticals used in the treatment of cancer and infectious diseases. The Company has one operating segment, being research and development. It operates only in Canada.
25GF Score
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