MLYS (Mineralys Therapeutics) EV-to-OCF: -12.93 (As of Aug. 09, 2026)

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MLYS Mineralys Therapeutics Inc MLYS
36 GF Score
Price $27.34
! 2 Warning Signs
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What is Mineralys Therapeutics EV-to-OCF?

Mineralys Therapeutics MLYS +1.33% 36 EV-to-OCF is -12.93 as of Aug. 09, 2026. GuruFocus rates MLYS with a GF Score™ of 36/100. The stock has 2 warning signs investors should review. Among 1,407 Biotechnology companies, Mineralys Therapeutics ranks better than 74.34% on this metric.

EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, Mineralys Therapeutics's Enterprise Value is $1,764.19 Mil. Mineralys Therapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 was $-136.40 Mil. Therefore, Mineralys Therapeutics's EV-to-OCF for today is -12.93.

The historical rank and industry rank for Mineralys Therapeutics's EV-to-OCF or its related term are showing as below:

MLYS' s EV-to-OCF Range Over the Past 10 Years
Min: -12.93   Med: 0   Max: -12.93
Current: -12.93

During the past 6 years, the highest EV-to-OCF of Mineralys Therapeutics was -12.93. The lowest was -12.93. And the median was .

MLYS's EV-to-OCF is ranked better than
74.34% of 1407 companies
in the Biotechnology industry
Industry Median: -3.45 vs MLYS: -12.93

EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

As of today (2026-08-09), Mineralys Therapeutics's stock price is $27.34. Mineralys Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 was $-2.050. Therefore, Mineralys Therapeutics's PE Ratio (TTM) for today is At Loss.


Mineralys Therapeutics  (NAS:MLYS) EV-to-OCF Explanation

EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Mineralys Therapeutics's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=27.34/-2.050
=At Loss

Mineralys Therapeutics's share price for today is $27.34.
Mineralys Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-2.050.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.


Mineralys Therapeutics EV-to-OCF Related Terms


Mineralys Therapeutics EV-to-OCF Historical Data

* Premium members only.

The historical data trend for Mineralys Therapeutics's EV-to-OCF can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Mineralys Therapeutics EV-to-OCF Chart

Mineralys Therapeutics Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-OCF
Get a 7-Day Free Trial 0.00 0.00 -1.44 -2.50 -16.17

Mineralys Therapeutics Quarterly Data
Dec20 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
EV-to-OCF Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -3.57 -2.93 -14.01 -16.17 -11.64

MLYS vs NKTR, PHVS, VCEL: EV-to-OCF Comparison

For the Biotechnology subindustry, Mineralys Therapeutics's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Mineralys Therapeutics EV-to-OCF vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Mineralys Therapeutics's EV-to-OCF distribution charts can be found below:

* The bar in red indicates where Mineralys Therapeutics's EV-to-OCF falls into.


MLYS
36GF Score
Mineralys Therapeutics Inc MLYS
EV-to-OCF is just one metric. See GF Score™, valuation, warning signs, and more.
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Mineralys Therapeutics EV-to-OCF Calculation

Mineralys Therapeutics's EV-to-OCF for today is calculated as:

EV-to-OCF=Enterprise Value (Today)/Cash Flow from Operations (TTM)
=1764.193/-136.4
=-12.93

Mineralys Therapeutics's current Enterprise Value is $1,764.19 Mil.
Mineralys Therapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-136.40 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-OCF →
What does a EV-to-OCF of -12.93 mean?
Mineralys Therapeutics (MLYS) has a EV-to-OCF of -12.93 as of Aug. 09, 2026. According to the industry distribution chart, Mineralys Therapeutics ranks #361 out of 1407 companies in the Biotechnology industry, placing it in the top 25.7%.
Is Mineralys Therapeutics' EV-to-OCF too high?
Mineralys Therapeutics' current EV-to-OCF is -12.93. Based on the distribution chart, Mineralys Therapeutics ranks #361 out of 1407 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Mineralys Therapeutics has a GF Score™ of 36/100, reflecting its overall financial health beyond just this single metric.
How does Mineralys Therapeutics' EV-to-OCF compare to NKTR and PHVS?
According to the Biotechnology industry distribution chart, Mineralys Therapeutics ranks #361 out of 1407 companies for EV-to-OCF. This puts Mineralys Therapeutics in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Biotechnology company?
A good EV-to-OCF depends on the Biotechnology industry context. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. Mineralys Therapeutics's current EV-to-OCF is -12.93. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Mineralys Therapeutics stock overvalued right now?
Mineralys Therapeutics (MLYS) has a current EV-to-OCF of -12.93. The current EV-to-OCF is -12.93. Mineralys Therapeutics' overall GF Score™ is 36/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For Mineralys Therapeutics (MLYS), the current EV-to-OCF is -12.93 as of Aug. 09, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Mineralys Therapeutics Business Description

Address 150 North Radnor Chester Road, Suite F200, Radnor, PA, USA, 19087
Mineralys Therapeutics Inc is a biopharmaceutical company focused on developing medicines to target diseases driven by dysregulated aldosterone. The Company's product candidate, lorundrostat, is a proprietary, orally administered, aldosterone synthase inhibitor that the Company is developing for the treatment of cardiorenal conditions affected by dysregulated aldosterone, including hypertension and related comorbidities, such as chronic kidney disease and obstructive sleep apnea. Its product candidate, lorundrostat, is a proprietary, orally administered, selective ASI that is designed to reduce aldosterone levels by inhibiting CYP11B2, the enzyme responsible for producing the hormone.
36GF Score

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$27.34
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