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Oruka TherapeuticsORKA -3.01%12 EV-to-OCF is -51.31 as of Sep. 10, 2026. GuruFocus rates ORKA with a GF Score™ of 12/100. The stock has 1 warning sign investors should review. Among 1,404 Biotechnology companies, Oruka Therapeutics ranks better than 92.52% on this metric.
EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, Oruka Therapeutics's Enterprise Value is $5,177.90 Mil.
Oruka Therapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 was $-100.92 Mil. Therefore, Oruka Therapeutics's EV-to-OCF for today is -51.31.
The historical rank and industry rank for Oruka Therapeutics's EV-to-OCF or its related term are showing as below:
ORKA'
s EV-to-OCF Range Over the Past 10 Years
Min: -51.31 Med: 0 Max: -51.31
Current: -51.31
During the past 2 years, the highest EV-to-OCF of Oruka Therapeutics was -51.31. The lowest was -51.31. And the median was .
ORKA's EV-to-OCF is ranked better than 92.52% of 1404
companies
in the Biotechnology industry
Industry Median: -3.45
vs ORKA: -51.31
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
Oruka Therapeutics's PE Ratio (TTM) for today is calculated as:
Oruka Therapeutics's share price for today is $91.36.
Oruka Therapeutics's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-2.030.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.
Oruka Therapeutics EV-to-OCF Related Terms
Oruka Therapeutics EV-to-OCF Historical Data
* Premium members only.
The historical data trend for Oruka Therapeutics's EV-to-OCF can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Oruka Therapeutics's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Oruka Therapeutics EV-to-OCF vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Oruka Therapeutics's EV-to-OCF distribution charts can be found below:
* The bar in red indicates where Oruka Therapeutics's EV-to-OCF falls into.
Oruka Therapeutics's current Enterprise Value is $5,177.90 Mil.
Oruka Therapeutics's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-100.92 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Oruka Therapeutics (ORKA) has a EV-to-OCF of -51.31 as of Sep. 10, 2026. According to the industry distribution chart, Oruka Therapeutics ranks #105 out of 1404 companies in the Biotechnology industry, placing it in the top 7.5%.
Is Oruka Therapeutics' EV-to-OCF too high?
Oruka Therapeutics' current EV-to-OCF is -51.31. Based on the distribution chart, Oruka Therapeutics ranks #105 out of 1404 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Oruka Therapeutics has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does Oruka Therapeutics' EV-to-OCF compare to COGT and MIRM?
According to the Biotechnology industry distribution chart, Oruka Therapeutics ranks #105 out of 1404 companies for EV-to-OCF. This places Oruka Therapeutics in the top 8% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Biotechnology company?
A good EV-to-OCF depends on the Biotechnology industry context. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. Oruka Therapeutics's current EV-to-OCF is -51.31. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Oruka Therapeutics stock overvalued right now?
Oruka Therapeutics (ORKA) has a current EV-to-OCF of -51.31. The current EV-to-OCF is -51.31. Oruka Therapeutics' overall GF Score™ is 12/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For Oruka Therapeutics (ORKA), the current EV-to-OCF is -51.31 as of Sep. 10, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Oruka Therapeutics Inc a clinical-stage biopharmaceutical company focused on developing novel monoclonal antibody therapeutics for psoriasis (PsO) and other inflammatory and immunology (I&I) indications. Its programs are to treat and potentially modify disease by targeting mechanisms with efficacy and safety involved in disease pathology and the activity of pathogenic tissue-resident memory T cells (TRMs). Its program, ORKA-001, is designed to target the p19 subunit of interleukin-23 (IL-23p19) for the treatment of PsO. Its co-lead program, ORKA-002, is designed to target interleukin-17A and interleukin-17F (IL-17A/F) for the treatment of PsO, hidradenitis suppurativa (HS), psoriatic arthritis (PsA), and other conditions.
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