STRO (Sutro Biopharma) EV-to-OCF: -1.28 (As of Aug. 16, 2026)

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STRO Sutro Biopharma Inc STRO
45 GF Score
Price $20.46
GF Value $5.50
Valuation Significantly Overvalued
! 4 Warning Signs
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What is Sutro Biopharma EV-to-OCF?

Sutro Biopharma STRO -4.16% 45 EV-to-OCF is -1.28 as of Aug. 16, 2026. GuruFocus rates STRO with a GF Score™ of 45/100 and a GF Value™ of $5.50 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 1,411 Biotechnology companies, Sutro Biopharma ranks worse than 62.37% on this metric.

EV-to-OCF is calculated as enterprise value divided by its cash flow from operations. As of today, Sutro Biopharma's Enterprise Value is $185.70 Mil. Sutro Biopharma's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 was $-145.17 Mil. Therefore, Sutro Biopharma's EV-to-OCF for today is -1.28.

The historical rank and industry rank for Sutro Biopharma's EV-to-OCF or its related term are showing as below:

STRO' s EV-to-OCF Range Over the Past 10 Years
Min: -11.51   Med: 0.08   Max: 52.06
Current: -1.28

During the past 10 years, the highest EV-to-OCF of Sutro Biopharma was 52.06. The lowest was -11.51. And the median was 0.08.

STRO's EV-to-OCF is ranked worse than
62.37% of 1411 companies
in the Biotechnology industry
Industry Median: -3.63 vs STRO: -1.28

EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

As of today (2026-08-16), Sutro Biopharma's stock price is $20.461. Sutro Biopharma's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 was $-17.360. Therefore, Sutro Biopharma's PE Ratio (TTM) for today is At Loss.


Sutro Biopharma  (NAS:STRO) EV-to-OCF Explanation

EV-to-OCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.

Sutro Biopharma's PE Ratio (TTM) for today is calculated as:

PE Ratio (TTM)=Share Price (Today)/Earnings per Share (Diluted) (TTM)
=20.461/-17.360
=At Loss

Sutro Biopharma's share price for today is $20.461.
Sutro Biopharma's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-17.360.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Cash Flow from Operations is an important financial metric because it represents the cash generated from operating activities at a company's disposal. Companies with a low EV-to-OCF ratio, combined with a strong balance sheet are generally considered as undervalued.


Sutro Biopharma EV-to-OCF Related Terms


Sutro Biopharma EV-to-OCF Historical Data

* Premium members only.

The historical data trend for Sutro Biopharma's EV-to-OCF can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Sutro Biopharma EV-to-OCF Chart

Sutro Biopharma Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
EV-to-OCF
Get a 7-Day Free Trial Premium Member Only Premium Member Only -6.72 50.91 0.72 0.74 0.15

Sutro Biopharma Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
EV-to-OCF Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.50 0.34 0.15 -1.48 -2.73

STRO vs AVIR, IPSC, CCCC: EV-to-OCF Comparison

For the Biotechnology subindustry, Sutro Biopharma's EV-to-OCF, along with its competitors' market caps and EV-to-OCF data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Sutro Biopharma EV-to-OCF vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Sutro Biopharma's EV-to-OCF distribution charts can be found below:

* The bar in red indicates where Sutro Biopharma's EV-to-OCF falls into.


STRO
45GF Score
Sutro Biopharma Inc STRO
EV-to-OCF is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Sutro Biopharma EV-to-OCF Calculation

Sutro Biopharma's EV-to-OCF for today is calculated as:

EV-to-OCF=Enterprise Value (Today)/Cash Flow from Operations (TTM)
=185.704/-145.173
=-1.28

Sutro Biopharma's current Enterprise Value is $185.70 Mil.
Sutro Biopharma's Cash Flow from Operations for the trailing twelve months (TTM) ended in Jun. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-145.17 Mil.

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about EV-to-OCF →
What does a EV-to-OCF of -1.28 mean?
Sutro Biopharma (STRO) has a EV-to-OCF of -1.28 as of Aug. 16, 2026. According to the industry distribution chart, Sutro Biopharma ranks #880 out of 1411 companies in the Biotechnology industry, placing it in the top 62.4%.
Is Sutro Biopharma's EV-to-OCF too high?
Sutro Biopharma's current EV-to-OCF is -1.28. Based on the distribution chart, Sutro Biopharma ranks #880 out of 1411 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Sutro Biopharma has a GF Score™ of 45/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Sutro Biopharma's EV-to-OCF compare to AVIR and IPSC?
According to the Biotechnology industry distribution chart, Sutro Biopharma ranks #880 out of 1411 companies for EV-to-OCF. This places Sutro Biopharma in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-OCF for a Biotechnology company?
A good EV-to-OCF depends on the Biotechnology industry context. However, EV-to-OCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-OCF mean?
A high EV-to-OCF can signal that a stock is expensive relative to its fundamentals. Sutro Biopharma's current EV-to-OCF is -1.28. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Sutro Biopharma stock overvalued right now?
Based on GuruFocus' analysis, Sutro Biopharma (STRO) is currently considered Significantly Overvalued. The stock's GF Value™ is $5.50, compared to a current price of $20.46 — trading 272% above its estimated fair value. The current EV-to-OCF is -1.28. Sutro Biopharma's overall GF Score™ is 45/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-OCF calculated?
EV-to-OCF is calculated from a company's financial statements. For Sutro Biopharma (STRO), the current EV-to-OCF is -1.28 as of Aug. 16, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Sutro Biopharma (STRO) Overvalued in 2026?

Based on GuruFocus' analysis, Sutro Biopharma stock appears to be overvalued. The current stock price of $20.46 is trading 272% above its estimated GF Value™ of $5.50. GuruFocus considers Sutro Biopharma to be Significantly Overvalued.

Key valuation signals for STRO:

  • EV-to-OCF: -1.28
  • GF Value™: $5.50 vs. price of $20.46 (272% above fair value)
  • GF Score™: 45/100 with 4 warning signs

No single metric tells the full story. See the STRO stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Sutro Biopharma Business Description

Other Exchanges S090:Germany
Address 111 Oyster Point Boulevard, South San Francisco, CA, USA, 94080
Sutro Biopharma Inc is a clinical-stage drug discovery, development, and manufacturing company. The company manufactures next-generation protein therapeutics for cancer and autoimmune disorders through its proprietary integrated cell-free protein synthesis platform, XpressCF. Products offered by the company include STRO-001 for patients with multiple myeloma and lymphoma and STRO-002 for the treatment of ovarian and endometrial cancers. Company's wholly-owned product candidate is STRO-004, a single homogeneous ADC directed against tissue factor which are developing for the treatment of solid tumors. The company also pipeline contains STRO-006, STRO-00X, STRO-00Y, STRO-003, VAX24, VAX31, and Others.
45GF Score

Get the complete analysis for STRO

EV-to-OCF is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$20.46
Price
$5.50
GF Value