Think of Enterprise Value as the theoretical takeover price. It is more comprehensive than market capitalization (Market Cap), which only includes common equity. Enterprise Value is calculated as the market cap plus debt and minority interest and preferred shares, minus total cash, cash equivalents, and marketable securities.
EV-to-EBIT is calculated as Enterprise Value divided by its EBIT. As of today, Vertex Pharmaceuticals's Enterprise Value is €105,134 Mil.
Vertex Pharmaceuticals's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 was €4,350 Mil. Therefore, Vertex Pharmaceuticals's EV-to-EBIT ratio for today is 24.17.
EV-to-EBITDA is calculated as Enterprise Value divided by its EBITDA. As of today, Vertex Pharmaceuticals's Enterprise Value is €105,134 Mil.
Vertex Pharmaceuticals's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 was €4,536 Mil. Therefore, Vertex Pharmaceuticals's EV-to-EBITDA ratio for today is 23.18.
*** Please note that the current Enterprise Value is calculated using the current market capitalization and the most recently available financial data. If key financial fields—Long-Term Debt & Capital Lease Obligation and Short-Term Debt & Capital Lease Obligation—are recorded as null in the latest reporting period, our data vendor will default to using data from the prior period with valid entries.
Vertex Pharmaceuticals (CHIX:VX1d) Enterprise Value Explanation
When an investor buy a company, the investor needs to pay not only the common shares, he/she also needs to pay the shareholders of Preferred Stocks. He also assumes the debt of the company, and receives the cash on the company's balance sheet.
If a company has more cash than debt, the investor actually pays less than the Market Cap because he immediately owns the cash once the transaction goes through.
The market value of Preferred Stock needs to be added to the market value of common stocks in the calculation of Enterprise Value.
For the companies with the same Market Cap, the smaller the Enterprise Value is, the cheaper the company is.
Enterprise Value can be negative when the company's net cash is more than its Market Cap. In this case the investor is basically getting the company for free and get paid for that.
1. EV-to-EBIT is calculated as Enterprise Value divided by its EBIT.
Vertex Pharmaceuticals's current Enterprise Value is €105,134 Mil.
Vertex Pharmaceuticals's EBIT for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was €4,350 Mil.
2. EV-to-EBITDA is calculated as Enterprise Value divided by its EBITDA.
Vertex Pharmaceuticals's EV-to-EBITDA for today is:
Vertex Pharmaceuticals's current Enterprise Value is €105,134 Mil.
Vertex Pharmaceuticals's EBITDA for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was €4,536 Mil.
Vertex Pharmaceuticals's current Enterprise Value is €105,134 Mil.
Vertex Pharmaceuticals's Revenue for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was €10,499 Mil.
Vertex Pharmaceuticals's current Enterprise Value is €105,134 Mil.
Vertex Pharmaceuticals's Cash Flow from Operations for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was €3,649 Mil.
Vertex Pharmaceuticals's current Enterprise Value is €105,134 Mil.
Vertex Pharmaceuticals's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was €3,193 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Vertex Pharmaceuticals Enterprise Value Related Terms
Vertex Pharmaceuticals Enterprise Value Historical Data
* Premium members only.
The historical data trend for Vertex Pharmaceuticals's Enterprise Value can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
CHIX:VX1D vs REGN, ALNY, RVMD: Enterprise Value Comparison
For the Biotechnology subindustry, Vertex Pharmaceuticals's Enterprise Value, along with its competitors' market caps and Enterprise Value data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Vertex Pharmaceuticals Enterprise Value vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Vertex Pharmaceuticals's Enterprise Value distribution charts can be found below:
* The bar in red indicates where Vertex Pharmaceuticals's Enterprise Value falls into.
Vertex Pharmaceuticals Enterprise Value Calculation
Enterprise Value is calculated as the market cap plus debt and minority interest and preferred shares, minus total cash, cash equivalents, and marketable securities.
Vertex Pharmaceuticals's Enterprise Value for the fiscal year that ended in Dec. 2025 is calculated as
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
What does a Enterprise Value of €105,134 Mil mean?
Vertex Pharmaceuticals (CHIX:VX1D) has a Enterprise Value of €105,134 Mil as of Jun. 27, 2026. Enterprise value equals the sum of market cap, debt and preferred shares less cash and equivalents. View historical data on Vertex Pharmaceuticals and its competitors.
Is Vertex Pharmaceuticals' Enterprise Value too high?
Vertex Pharmaceuticals' current Enterprise Value is €105,134 Mil. Overall, Vertex Pharmaceuticals has a GF Score™ of 87/100, reflecting its overall financial health beyond just this single metric.
How does Vertex Pharmaceuticals' Enterprise Value compare to REGN and ALNY?
Vertex Pharmaceuticals' Enterprise Value of €105,134 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Enterprise Value for a Biotechnology company?
A good Enterprise Value depends on the Biotechnology industry context. However, Enterprise Value should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Enterprise Value mean?
A high Enterprise Value can signal that a stock is expensive relative to its fundamentals. Enterprise value equals the sum of market cap, debt and preferred shares less cash and equivalents. View historical data on Vertex Pharmaceuticals and its competitors. Vertex Pharmaceuticals's current Enterprise Value is €105,134 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Vertex Pharmaceuticals stock overvalued right now?
Vertex Pharmaceuticals (CHIX:VX1D) has a current Enterprise Value of €105,134 Mil. The stock's GF Value™ is €329.60, compared to a current price of €322.40 — trading 2.2% below its estimated fair value. The current Enterprise Value is €105,134 Mil. Vertex Pharmaceuticals' overall GF Score™ is 87/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Enterprise Value calculated?
Enterprise Value is calculated from a company's financial statements. For Vertex Pharmaceuticals (CHIX:VX1D), the current Enterprise Value is €105,134 Mil as of Jun. 27, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Vertex Pharmaceuticals (CHIX:VX1D) Overvalued in 2026?
Based on GuruFocus' analysis, Vertex Pharmaceuticals stock appears to be undervalued.
The current stock price of €322.40 is trading 2.2% below its estimated GF Value™ of €329.60.
Key valuation signals for CHIX:VX1D:
Enterprise Value: €105,134 Mil
GF Value™: €329.60 vs. price of €322.40 (2.2% below fair value)
No single metric tells the full story. See the CHIX:VX1D stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Vertex Pharmaceuticals is a global biotechnology company that discovers and develops small-molecule drugs for the treatment of serious diseases. Its key drugs are Kalydeco, Orkambi, Symdeko, and Trikafta/Kaftrio, and Alyftrek for cystic fibrosis, where Vertex therapies remain the standard of care globally. Vertex has diversified its portfolio through Casgevy, a gene-editing therapy for beta thalassemia and sickle-cell disease, and Journavx, a non-opioid pain medication approved for the treatment of moderate-to-severe acute pain in adults. Additionally, Vertex is evaluating small-molecule inhibitors of APOL1-mediated kidney diseases. Vertex is also investigating cell therapies to deliver a potential functional cure for type 1 diabetes.
87GF Score
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