aTyr PharmaATYR +3.19%14 EV-to-FCF is -0.19 as of Jul. 07, 2026. GuruFocus rates ATYR with a GF Score™ of 14/100 and a GF Value™ of $0.46 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 329 Biotechnology companies, aTyr Pharma ranks worse than 303951.06% on this metric.
EV-to-FCF is calculated as enterprise value divided by its free cash flow. As of today, aTyr Pharma's Enterprise Value is $11.24 Mil.
aTyr Pharma's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 was $-59.22 Mil. Therefore, aTyr Pharma's EV-to-FCF for today is -0.19.
The historical rank and industry rank for aTyr Pharma's EV-to-FCF or its related term are showing as below:
ATYR'
s EV-to-FCF Range Over the Past 10 Years
Min: -6.36 Med: -0.22 Max: 2.49
Current: -0.19
During the past 13 years, the highest EV-to-FCF of aTyr Pharma was 2.49. The lowest was -6.36. And the median was -0.22.
ATYR's EV-to-FCF is ranked worse than 100% of 329
companies
in the Biotechnology industry
Industry Median: 16.38
vs ATYR: -0.19
EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
EV-to-FCF is a valuation multiple that allows analysts and investors to compare stocks, preferably in the same sector or industry. This important multiple is often used in conjunction with, or as an alternative to, the PE Ratio (TTM) to determine the fair market value of a company.
aTyr Pharma's PE Ratio (TTM) for today is calculated as:
aTyr Pharma's share price for today is $0.67565.
aTyr Pharma's Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-0.730.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Enterprise Value is used because it is a more complete measure in reflecting how much an investor pays when buying a company. Free Cash Flow is an important financial metric because it represents the actual amount of cash at a company's disposal. Companies with a low EV-to-FCF ratio, combined with a strong balance sheet are generally considered as undervalued.
aTyr Pharma EV-to-FCF Related Terms
aTyr Pharma EV-to-FCF Historical Data
* Premium members only.
The historical data trend for aTyr Pharma's EV-to-FCF can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, aTyr Pharma's EV-to-FCF, along with its competitors' market caps and EV-to-FCF data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
aTyr Pharma EV-to-FCF vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, aTyr Pharma's EV-to-FCF distribution charts can be found below:
* The bar in red indicates where aTyr Pharma's EV-to-FCF falls into.
aTyr Pharma's current Enterprise Value is $11.24 Mil.
aTyr Pharma's Free Cash Flow for the trailing twelve months (TTM) ended in Mar. 2026 adds up the quarterly data reported by the company within the most recent 12 months, which was $-59.22 Mil.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
aTyr Pharma (ATYR) has a EV-to-FCF of -0.19 as of Jul. 07, 2026. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on aTyr Pharma and its competitors. According to the industry distribution chart, aTyr Pharma ranks #999999 out of 329 companies in the Biotechnology industry.
Is aTyr Pharma's EV-to-FCF too high?
aTyr Pharma's current EV-to-FCF is -0.19. Based on the distribution chart, aTyr Pharma ranks #999999 out of 329 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, aTyr Pharma has a GF Score™ of 14/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does aTyr Pharma's EV-to-FCF compare to DWTX and CNTX?
According to the Biotechnology industry distribution chart, aTyr Pharma ranks #999999 out of 329 companies for EV-to-FCF. This places aTyr Pharma in the lower half of its industry. The industry median EV-to-FCF is 16.38. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good EV-to-FCF for a Biotechnology company?
The median EV-to-FCF among Biotechnology companies is 16.38, based on 329 companies in the industry. Companies in the top quartile (top 25%) have a EV-to-FCF significantly above this median, while those in the bottom quartile fall well below. However, EV-to-FCF should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high EV-to-FCF mean?
A high EV-to-FCF can signal that a stock is expensive relative to its fundamentals. EV to FCF ratio is the company's enterprise value divided by free cash flow. View historical data on aTyr Pharma and its competitors. For the Biotechnology industry, the median EV-to-FCF is 16.38 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. aTyr Pharma's current EV-to-FCF is -0.19. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is aTyr Pharma stock overvalued right now?
Based on GuruFocus' analysis, aTyr Pharma (ATYR) is currently considered Significantly Overvalued. The stock's GF Value™ is $0.46, compared to a current price of $0.68 — trading 46.9% above its estimated fair value. The current EV-to-FCF is -0.19. aTyr Pharma's overall GF Score™ is 14/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is EV-to-FCF calculated?
EV-to-FCF is calculated from a company's financial statements. For aTyr Pharma (ATYR), the current EV-to-FCF is -0.19 as of Jul. 07, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is aTyr Pharma (ATYR) Overvalued in 2026?
Based on GuruFocus' analysis, aTyr Pharma stock appears to be overvalued.
The current stock price of $0.68 is trading 46.9% above its estimated GF Value™ of $0.46.
GuruFocus considers aTyr Pharma to be Significantly Overvalued.
Key valuation signals for ATYR:
EV-to-FCF: -0.19
GF Value™: $0.46 vs. price of $0.68 (46.9% above fair value)
No single metric tells the full story. See the ATYR stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
aTyr Pharma Inc is a clinical-stage biotechnology company focused on developing therapies for fibrosis and inflammatory conditions. Its research leverages tRNA synthetase biology to identify potential therapeutic targets. The company's discovery platform uses a proprietary library of domains derived from tRNA synthetases to explore signaling pathways. Its flagship clinical candidate, efzofitimod, is a novel biologic immunomodulatory in development for the treatment of interstitial lung disease (ILD).
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