ATYR (aTyr Pharma) Shiller PE Ratio: (As of Sep. 09, 2026)

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ATYR aTyr Pharma Inc ATYR
16 GF Score
Price $0.46
GF Value $0.52
Valuation Modestly Undervalued
! 3 Warning Signs
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What is aTyr Pharma Shiller PE Ratio?

Shiller PE for Stocks: The True Measure of Stock Valuation


aTyr Pharma  (NAS:ATYR) Shiller PE Ratio Explanation

Compared with the regular PE Ratio, which works poorly for cyclical businesses, the Shiller PE Ratio smoothed out the fluctuations of profit margins during business cycles. Therefore it is more accurate in reflecting the valuation of the company.

If a company has consistent business performance, the Shiller PE Ratio should give similar results to regular PE Ratio.

Compared with the PS Ratio, the Shiller PE Ratio makes the comparison between different industries more meaningful.


Be Aware

Shiller PE Ratio assumes that over the long term, businesses and profitability revert to their means. If a company's business model does not work in the future compared with the past, Shiller PE Ratio and PS Ratio will give false valuations.


aTyr Pharma Shiller PE Ratio Related Terms


aTyr Pharma Shiller PE Ratio Historical Data

* Premium members only.

The historical data trend for aTyr Pharma's Shiller PE Ratio can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

aTyr Pharma Shiller PE Ratio Chart

aTyr Pharma Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Shiller PE Ratio
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

aTyr Pharma Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
Shiller PE Ratio Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

ATYR vs TIL, AURX, ELOX: Shiller PE Ratio Comparison

For the Biotechnology subindustry, aTyr Pharma's Shiller PE Ratio, along with its competitors' market caps and Shiller PE Ratio data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


aTyr Pharma Shiller PE Ratio vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, aTyr Pharma's Shiller PE Ratio distribution charts can be found below:

* The bar in red indicates where aTyr Pharma's Shiller PE Ratio falls into.


ATYR
16GF Score
aTyr Pharma Inc ATYR
Shiller PE Ratio is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

aTyr Pharma Shiller PE Ratio Calculation

For Shiller PE Ratio, the earnings of the past 10 years are inflation-adjusted and averaged. The result is used for P/E calculation. Since it looks at the average over the last 10 years, the Shiller PE Ratio is also called PE10.

The Shiller PE Ratio was first used by professor Robert Shiller to measure the valuation of the overall market. The same calculation is applied here to individual companies.

aTyr Pharma's E10 for the quarter that ended in Jun. 2026 is calculated as:

For example, aTyr Pharma's adjusted earnings per share data for the three months ended in Jun. 2026 was:

Adj_EPS=Earnings per Share (Diluted)/CPI of Jun. 2026 (Change)*Current CPI (Jun. 2026)
=-0.11/333.9520*333.9520
=-0.110

Current CPI (Jun. 2026) = 333.9520.

aTyr Pharma Quarterly Data

Earnings per Share (Diluted) CPI Adj_EPS
201609 -8.120 241.428 -11.232
201612 -7.420 241.432 -10.263
201703 -7.840 243.801 -10.739
201706 -7.140 244.955 -9.734
201709 -6.020 246.819 -8.145
201712 -5.460 246.524 -7.396
201803 -5.040 249.554 -6.745
201806 -4.880 251.989 -6.467
201809 -3.330 252.439 -4.405
201812 -2.940 251.233 -3.908
201903 -2.540 254.202 -3.337
201906 -1.800 256.143 -2.347
201909 -1.470 256.759 -1.912
201912 -1.540 256.974 -2.001
202003 0.250 258.115 0.323
202006 -0.690 257.797 -0.894
202009 -0.680 260.280 -0.872
202012 -0.470 260.474 -0.603
202103 -0.510 264.877 -0.643
202106 -0.640 271.696 -0.787
202109 -0.420 274.310 -0.511
202112 -0.310 278.802 -0.371
202203 -0.440 287.504 -0.511
202206 -0.440 296.311 -0.496
202209 -0.460 296.808 -0.518
202212 -0.260 296.797 -0.293
202303 -0.290 301.836 -0.321
202306 -0.220 305.109 -0.241
202309 -0.200 307.789 -0.217
202312 -0.250 306.746 -0.272
202403 -0.230 312.332 -0.246
202406 -0.230 314.175 -0.244
202409 -0.230 315.301 -0.244
202412 -0.180 315.605 -0.190
202503 -0.170 319.799 -0.178
202506 -0.220 322.561 -0.228
202509 -0.260 324.800 -0.267
202512 -0.140 324.054 -0.144
202603 -0.110 330.213 -0.111
202606 -0.110 333.952 -0.110

Add all the adjusted EPS together and divide 10 will get our E10.

Please note that we use the CPI data of the country/region where the company is headquartered. If the CPI data for that country/region is not available, then we will use the CPI data of the United States as default.

Is aTyr Pharma (ATYR) Overvalued in 2026?

Based on GuruFocus' analysis, aTyr Pharma stock appears to be undervalued. The current stock price of $0.46 is trading 12.4% below its estimated GF Value™ of $0.52. GuruFocus considers aTyr Pharma to be Modestly Undervalued.

Key valuation signals for ATYR:

  • Shiller PE Ratio:
  • GF Value™: $0.52 vs. price of $0.46 (12.4% below fair value)
  • GF Score™: 16/100 with 3 warning signs

No single metric tells the full story. See the ATYR stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


aTyr Pharma Business Description

Other Exchanges 471A:Germany
Address 10240 Sorrento Valley Road, Suite 300, San Diego, CA, USA, 92121
aTyr Pharma Inc is a clinical-stage biotechnology company focused on developing therapies for fibrosis and inflammatory conditions. Its research leverages tRNA synthetase biology to identify potential therapeutic targets. The company's discovery platform uses a proprietary library of domains derived from tRNA synthetases to explore signaling pathways. Its flagship clinical candidate, efzofitimod, is a novel biologic immunomodulatory in development for the treatment of interstitial lung disease (ILD).
16GF Score

Get the complete analysis for ATYR

Shiller PE Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$0.46
Price
$0.52
GF Value