Nexalis Therapeutics (ASX:NX1) Piotroski F-Score: 1 (As of Jun. 27, 2026) — 50% Below Median


What is Nexalis Therapeutics Piotroski F-Score?

Nexalis Therapeutics ASX:NX1 Piotroski F-Score is 1 as of Jun. 27, 2026, which is 50% below its 10-year median of 2.00. The stock has 3 warning signs investors should review. Among 1,342 Biotechnology companies, Nexalis Therapeutics ranks worse than 92.32% on this metric.

Warning Sign:

Piotroski F-Score of 1 is low, which usually implies poor business operation.

The zones of discrimination were as such:

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Nexalis Therapeutics has an F-score of 1. It is a bad or low score, which usually implies poor business operation.

The historical rank and industry rank for Nexalis Therapeutics's Piotroski F-Score or its related term are showing as below:

ASX:NX1' s Piotroski F-Score Range Over the Past 10 Years
Min: 1   Med: 2   Max: 5
Current: 1

During the past 10 years, the highest Piotroski F-Score of Nexalis Therapeutics was 5. The lowest was 1. And the median was 2.

Nexalis Therapeutics  (ASX:NX1) Piotroski F-Score Explanation

The developer of the system is Joseph D. Piotroski is relatively unknown accounting professor who shuns publicity and rarely gives interviews.

He graduated from the University of Illinois with a B.S. in accounting in 1989, received an M.B.A. from Indiana University in 1994. Five years later, in 1999, after earning a Ph.D. in accounting from the University of Michigan, he became an associate professor of accounting at the University of Chicago.

In 2000, he wrote a research paper called "Value Investing: The Use of Historical Financial Statement Information to Separate Winners from Losers" (pdf).

He wanted to see if he can develop a system (using a simple nine-point scoring system) that can increase the returns of a strategy of investing in low price to book (referred to in the paper as high book to market) value companies.

What he found was something that exceeded his most optimistic expectations.

Buying only those companies that scored highest (8 or 9) on his nine-point scale, or F-Score as he called it, over the 20 year period from 1976 to 1996 led to an average out-performance over the market of 13.4%.

Even more impressive were the results of a strategy of investing in the highest F-Score companies (8 or 9) and shorting companies with the lowest F-Score (0 or 1).

Over the same period from 1976 to 1996 (20 years) this strategy led to an average yearly return of 23%, substantially outperforming the average S&P 500 index return of 15.83% over the same period.


Nexalis Therapeutics Piotroski F-Score Related Terms


Nexalis Therapeutics Piotroski F-Score Historical Data

* Premium members only.

The historical data trend for Nexalis Therapeutics's Piotroski F-Score can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Nexalis Therapeutics Piotroski F-Score Chart

Nexalis Therapeutics Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Piotroski F-Score
Get a 7-Day Free Trial Premium Member Only Premium Member Only 5.00 3.00 2.00 2.00 1.00

Nexalis Therapeutics Semi-Annual Data
Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Piotroski F-Score Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 2.00 0.00 2.00 0.00 1.00

ASX:NX1 vs VRTX, REGN, ALNY: Piotroski F-Score Comparison

For the Biotechnology subindustry, Nexalis Therapeutics's Piotroski F-Score, along with its competitors' market caps and Piotroski F-Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Nexalis Therapeutics Piotroski F-Score vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Nexalis Therapeutics's Piotroski F-Score distribution charts can be found below:

* The bar in red indicates where Nexalis Therapeutics's Piotroski F-Score falls into.


How is the Piotroski F-Score calculated?

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

This Year (Dec25) TTM:Last Year (Dec24) TTM:
Net Income was A$-1.62 Mil.
Cash Flow from Operations was A$-0.89 Mil.
Revenue was A$0.00 Mil.
Gross Profit was A$0.00 Mil.
Average Total Assets from the begining of this year (Dec24)
to the end of this year (Dec25) was (0.712 + 1.208) / 2 = A$0.96 Mil.
Total Assets at the begining of this year (Dec24) was A$0.71 Mil.
Long-Term Debt & Capital Lease Obligation was A$0.32 Mil.
Total Current Assets was A$1.21 Mil.
Total Current Liabilities was A$2.07 Mil.
Net Income was A$-1.21 Mil.

Revenue was A$0.00 Mil.
Gross Profit was A$0.00 Mil.
Average Total Assets from the begining of last year (Dec23)
to the end of last year (Dec24) was (1.577 + 0.712) / 2 = A$1.1445 Mil.
Total Assets at the begining of last year (Dec23) was A$1.58 Mil.
Long-Term Debt & Capital Lease Obligation was A$0.00 Mil.
Total Current Assets was A$0.71 Mil.
Total Current Liabilities was A$0.78 Mil.

*Note: If the latest quarterly/semi-annual/annual total assets data is 0, then we will use previous quarterly/semi-annual/annual data for all the items in the balance sheet.

Profitability

Question 1. Return on Assets (ROA)

Net income before extraordinary items for the year divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Nexalis Therapeutics's current Net Income (TTM) was -1.62. ==> Negative ==> Score 0.

Question 2. Cash Flow Return on Assets (CFROA)

Net cash flow from operating activities (operating cash flow) divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Nexalis Therapeutics's current Cash Flow from Operations (TTM) was -0.89. ==> Negative ==> Score 0.

Question 3. Change in Return on Assets

Compare this year's return on assets (1) to last year's return on assets.

Score 1 if it's higher, 0 if it's lower.

ROA (This Year)=Net Income/Total Assets (Dec24)
=-1.619/0.712
=-2.2738764

ROA (Last Year)=Net Income/Total Assets (Dec23)
=-1.209/1.577
=-0.76664553

Nexalis Therapeutics's return on assets of this year was -2.2738764. Nexalis Therapeutics's return on assets of last year was -0.76664553. ==> Last year is higher ==> Score 0.

Question 4. Quality of Earnings (Accrual)

Compare Cash flow return on assets (2) to return on assets (1)

Score 1 if CFROA > ROA, 0 if CFROA <= ROA.

Nexalis Therapeutics's current Net Income (TTM) was -1.62. Nexalis Therapeutics's current Cash Flow from Operations (TTM) was -0.89. ==> -0.89 > -1.62 ==> CFROA > ROA ==> Score 1.

Funding

Question 5. Change in Gearing or Leverage

Compare this year's gearing (long-term debt divided by average total assets) to last year's gearing.

Score 0 if this year's gearing is higher, 1 otherwise.

Gearing (This Year: Dec25)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Dec24 to Dec25
=0.315/0.96
=0.328125

Gearing (Last Year: Dec24)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Dec23 to Dec24
=0/1.1445
=0

Nexalis Therapeutics's gearing of this year was 0.328125. Nexalis Therapeutics's gearing of last year was 0. ==> Last year is lower than this year ==> Score 0.

Question 6. Change in Working Capital (Liquidity)

Compare this year's current ratio (current assets divided by current liabilities) to last year's current ratio.

Score 1 if this year's current ratio is higher, 0 if it's lower

Current Ratio (This Year: Dec25)=Total Current Assets/Total Current Liabilities
=1.208/2.067
=0.58442187

Current Ratio (Last Year: Dec24)=Total Current Assets/Total Current Liabilities
=0.712/0.776
=0.91752577

Nexalis Therapeutics's current ratio of this year was 0.58442187. Nexalis Therapeutics's current ratio of last year was 0.91752577. ==> Last year's current ratio is higher ==> Score 0.

Question 7. Change in Shares in Issue

Compare the number of shares in issue this year, to the number in issue last year.

Score 0 if there is larger number of shares in issue this year, 1 otherwise.

Nexalis Therapeutics's number of shares in issue this year was 215.683. Nexalis Therapeutics's number of shares in issue last year was 215.006. ==> There is larger number of shares in issue this year. ==> Score 0.

Efficiency

Question 8. Change in Gross Margin

Compare this year's gross margin (Gross Profit divided by sales) to last year's.

Score 1 if this year's gross margin is higher, 0 if it's lower.

Gross Margin (This Year: TTM)=Gross Profit/Revenue
=0/0
=

Gross Margin (Last Year: TTM)=Gross Profit/Revenue
=0/0
=

Nexalis Therapeutics's gross margin of this year was . Nexalis Therapeutics's gross margin of last year was . ==> Last year's gross margin is higher ==> Score 0.

Question 9. Change in asset turnover

Compare this year's asset turnover (total sales for the year divided by total assets at the beginning of the year) to last year's asset turnover ratio.

Score 1 if this year's asset turnover ratio is higher, 0 if it's lower

Asset Turnover (This Year)=Revenue/Total Assets at the Beginning of This Year (Dec24)
=0/0.712
=0

Asset Turnover (Last Year)=Revenue/Total Assets at the Beginning of Last Year (Dec23)
=0/1.577
=0

Nexalis Therapeutics's asset turnover of this year was 0. Nexalis Therapeutics's asset turnover of last year was 0. ==> Last year's asset turnover is higher ==> Score 0.

Evaluation

Piotroski F-Score= Que. 1+ Que. 2+ Que. 3+Que. 4+Que. 5+Que. 6+Que. 7+Que. 8+Que. 9
=0+0+0+1+0+0+0+0+0
=1

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Nexalis Therapeutics has an F-score of 1. It is a bad or low score, which usually implies poor business operation.

Frequently Asked Questions Learn more about Piotroski F-Score →
What does a Piotroski F-Score of 1 mean?
Nexalis Therapeutics (ASX:NX1) has a Piotroski F-Score of 1 as of Jun. 27, 2026. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Nexalis Therapeutics and its competitors. This is 50% below median its historical median of 2.00. Over the past decade, Nexalis Therapeutics' Piotroski F-Score has ranged from 1.00 to 5.00. According to the industry distribution chart, Nexalis Therapeutics ranks #1239 out of 1342 companies in the Biotechnology industry, placing it in the top 92.3%.
Is Nexalis Therapeutics' Piotroski F-Score too high?
Nexalis Therapeutics' current Piotroski F-Score of 1 is 50% below median its 10-year median of 2.00. Over the past 10 years, this metric has ranged from a low of 1.00 to a high of 5.00. The Biotechnology industry median Piotroski F-Score is 3.00. Nexalis Therapeutics' value of 1 is 66.7% below this industry median. Based on the distribution chart, Nexalis Therapeutics ranks #1239 out of 1342 companies in the Biotechnology industry, which is in the bottom quartile relative to peers.
How does Nexalis Therapeutics' Piotroski F-Score compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Nexalis Therapeutics ranks #1239 out of 1342 companies for Piotroski F-Score. This places Nexalis Therapeutics in the lower half of its industry. The industry median Piotroski F-Score is 3.00. Nexalis Therapeutics' value of 1 is 66.7% below this benchmark. Historically, Nexalis Therapeutics' own Piotroski F-Score has ranged from 1.00 to 5.00 over the past decade. While the company's 10-year median is 2.00 vs. the industry median of 3.00, Nexalis Therapeutics has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Piotroski F-Score for a Biotechnology company?
The median Piotroski F-Score among Biotechnology companies is 3.00, based on 1,342 companies in the industry. Companies in the top quartile (top 25%) have a Piotroski F-Score significantly above this median, while those in the bottom quartile fall well below. However, Piotroski F-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Nexalis Therapeutics's current Piotroski F-Score of 1 is 66.7% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Piotroski F-Score mean?
A high Piotroski F-Score can signal that a stock is expensive relative to its fundamentals. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Nexalis Therapeutics and its competitors. For the Biotechnology industry, the median Piotroski F-Score is 3.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Nexalis Therapeutics's current Piotroski F-Score is 1, which is 50% below median its own 10-year median of 2.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Nexalis Therapeutics stock overvalued right now?
Nexalis Therapeutics (ASX:NX1) has a current Piotroski F-Score of 1. The current Piotroski F-Score is 1, which is 50% below median its 10-year median of 2.00 and 66.7% below the Biotechnology industry median of 3.00. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Piotroski F-Score calculated?
Piotroski F-Score is calculated from a company's financial statements. For Nexalis Therapeutics (ASX:NX1), the current Piotroski F-Score is 1 as of Jun. 27, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Nexalis Therapeutics Business Description

Address 505 Little Collins Street, Level 9, Melbourne, VIC, AUS, 3000
Nexalis Therapeutics Ltd is an Australian clinical-stage drug development company that is focused on developing therapies to address unmet medical needs in pain management and mental health sectors. Its pipeline includes three clinical drug candidates focused on treatment-resistant depression (SRX-25), breakthrough cancer pain (IRX-211), and panic disorder (IRX-616a), each addressing areas of unmet medical need and potential commercial demand.