Clene (FRA:84C0) Piotroski F-Score: 3 (As of Jun. 28, 2026) — Near Median


FRA:84C0 Clene Inc FRA:84C0
33 GF Score
Price €4.90
GF Value €0.72
Valuation Significantly Overvalued
! 9 Warning Signs
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What is Clene Piotroski F-Score?

Clene FRA:84C0 +1.24% 33 Piotroski F-Score is 3 as of Jun. 28, 2026, which is at its 10-year median of 3.00. GuruFocus rates FRA:84C0 with a GF Score™ of 33/100 and a GF Value™ of €0.72 (Significantly Overvalued). The stock has 9 warning signs investors should review. Among 1,910 Consumer Packaged Goods companies, Clene ranks worse than 84.82% on this metric.

Warning Sign:

Piotroski F-Score of 3 is low, which usually implies poor business operation.

The zones of discrimination were as such:

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Clene has an F-score of 3. It is a bad or low score, which usually implies poor business operation.

The historical rank and industry rank for Clene's Piotroski F-Score or its related term are showing as below:

FRA:84C0' s Piotroski F-Score Range Over the Past 10 Years
Min: 1   Med: 3   Max: 4
Current: 3

During the past 7 years, the highest Piotroski F-Score of Clene was 4. The lowest was 1. And the median was 3.

Clene  (FRA:84C0) Piotroski F-Score Explanation

The developer of the system is Joseph D. Piotroski is relatively unknown accounting professor who shuns publicity and rarely gives interviews.

He graduated from the University of Illinois with a B.S. in accounting in 1989, received an M.B.A. from Indiana University in 1994. Five years later, in 1999, after earning a Ph.D. in accounting from the University of Michigan, he became an associate professor of accounting at the University of Chicago.

In 2000, he wrote a research paper called "Value Investing: The Use of Historical Financial Statement Information to Separate Winners from Losers" (pdf).

He wanted to see if he can develop a system (using a simple nine-point scoring system) that can increase the returns of a strategy of investing in low price to book (referred to in the paper as high book to market) value companies.

What he found was something that exceeded his most optimistic expectations.

Buying only those companies that scored highest (8 or 9) on his nine-point scale, or F-Score as he called it, over the 20 year period from 1976 to 1996 led to an average out-performance over the market of 13.4%.

Even more impressive were the results of a strategy of investing in the highest F-Score companies (8 or 9) and shorting companies with the lowest F-Score (0 or 1).

Over the same period from 1976 to 1996 (20 years) this strategy led to an average yearly return of 23%, substantially outperforming the average S&P 500 index return of 15.83% over the same period.


Clene Piotroski F-Score Related Terms


Clene Piotroski F-Score Historical Data

* Premium members only.

The historical data trend for Clene's Piotroski F-Score can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Clene Piotroski F-Score Chart

Clene Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Piotroski F-Score
Get a 7-Day Free Trial 2.00 1.00 3.00 3.00 2.00

Clene Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Piotroski F-Score Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 4.00 3.00 3.00 2.00 3.00

FRA:84C0 vs BHST, GWLL, FTLF: Piotroski F-Score Comparison

For the Packaged Foods subindustry, Clene's Piotroski F-Score, along with its competitors' market caps and Piotroski F-Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Clene Piotroski F-Score vs Consumer Packaged Goods Industry

For the Consumer Packaged Goods industry and Consumer Defensive sector, Clene's Piotroski F-Score distribution charts can be found below:

* The bar in red indicates where Clene's Piotroski F-Score falls into.


FRA:84C0
33GF Score
Clene Inc FRA:84C0
Piotroski F-Score is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

How is the Piotroski F-Score calculated?

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

This Year (Mar26) TTM:Last Year (Mar25) TTM:
Net Income was -6.432 + -7.478 + -7.879 + -6.999 = €-28.79 Mil.
Cash Flow from Operations was -4.113 + -3.401 + -4.098 + -3.917 = €-15.53 Mil.
Revenue was 0.023 + 0.013 + 0.066 + 0.013 = €0.12 Mil.
Gross Profit was 0.023 + 0.013 + 0.046 + 0.013 = €0.10 Mil.
Average Total Assets from the begining of this year (Mar25)
to the end of this year (Mar26) was
(23.415 + 19.182 + 19.009 + 15.484 + 18.74) / 5 = €19.166 Mil.
Total Assets at the begining of this year (Mar25) was €23.42 Mil.
Long-Term Debt & Capital Lease Obligation was €16.74 Mil.
Total Current Assets was €11.27 Mil.
Total Current Liabilities was €5.82 Mil.
Net Income was -6.303 + -7.195 + -12.939 + -0.695 = €-27.13 Mil.

Revenue was 0.085 + 0.078 + 0.087 + 0.075 = €0.33 Mil.
Gross Profit was 0.068 + 0.062 + 0.07 + 0.056 = €0.26 Mil.
Average Total Assets from the begining of last year (Mar24)
to the end of last year (Mar25) was
(41.463 + 37.467 + 28.444 + 26.107 + 23.415) / 5 = €31.3792 Mil.
Total Assets at the begining of last year (Mar24) was €41.46 Mil.
Long-Term Debt & Capital Lease Obligation was €15.57 Mil.
Total Current Assets was €13.57 Mil.
Total Current Liabilities was €9.96 Mil.

*Note: If the latest quarterly/semi-annual/annual total assets data is 0, then we will use previous quarterly/semi-annual/annual data for all the items in the balance sheet.

Profitability

Question 1. Return on Assets (ROA)

Net income before extraordinary items for the year divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Clene's current Net Income (TTM) was -28.79. ==> Negative ==> Score 0.

Question 2. Cash Flow Return on Assets (CFROA)

Net cash flow from operating activities (operating cash flow) divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Clene's current Cash Flow from Operations (TTM) was -15.53. ==> Negative ==> Score 0.

Question 3. Change in Return on Assets

Compare this year's return on assets (1) to last year's return on assets.

Score 1 if it's higher, 0 if it's lower.

ROA (This Year)=Net Income/Total Assets (Mar25)
=-28.788/23.415
=-1.22946829

ROA (Last Year)=Net Income/Total Assets (Mar24)
=-27.132/41.463
=-0.65436654

Clene's return on assets of this year was -1.22946829. Clene's return on assets of last year was -0.65436654. ==> Last year is higher ==> Score 0.

Question 4. Quality of Earnings (Accrual)

Compare Cash flow return on assets (2) to return on assets (1)

Score 1 if CFROA > ROA, 0 if CFROA <= ROA.

Clene's current Net Income (TTM) was -28.79. Clene's current Cash Flow from Operations (TTM) was -15.53. ==> -15.53 > -28.79 ==> CFROA > ROA ==> Score 1.

Funding

Question 5. Change in Gearing or Leverage

Compare this year's gearing (long-term debt divided by average total assets) to last year's gearing.

Score 0 if this year's gearing is higher, 1 otherwise.

Gearing (This Year: Mar26)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Mar25 to Mar26
=16.743/19.166
=0.87357821

Gearing (Last Year: Mar25)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Mar24 to Mar25
=15.572/31.3792
=0.49625229

Clene's gearing of this year was 0.87357821. Clene's gearing of last year was 0.49625229. ==> Last year is lower than this year ==> Score 0.

Question 6. Change in Working Capital (Liquidity)

Compare this year's current ratio (current assets divided by current liabilities) to last year's current ratio.

Score 1 if this year's current ratio is higher, 0 if it's lower

Current Ratio (This Year: Mar26)=Total Current Assets/Total Current Liabilities
=11.265/5.821
=1.9352345

Current Ratio (Last Year: Mar25)=Total Current Assets/Total Current Liabilities
=13.571/9.957
=1.36296073

Clene's current ratio of this year was 1.9352345. Clene's current ratio of last year was 1.36296073. ==> This year's current ratio is higher. ==> Score 1.

Question 7. Change in Shares in Issue

Compare the number of shares in issue this year, to the number in issue last year.

Score 0 if there is larger number of shares in issue this year, 1 otherwise.

Clene's number of shares in issue this year was 11.644. Clene's number of shares in issue last year was 8.825. ==> There is larger number of shares in issue this year. ==> Score 0.

Efficiency

Question 8. Change in Gross Margin

Compare this year's gross margin (Gross Profit divided by sales) to last year's.

Score 1 if this year's gross margin is higher, 0 if it's lower.

Gross Margin (This Year: TTM)=Gross Profit/Revenue
=0.095/0.115
=0.82608696

Gross Margin (Last Year: TTM)=Gross Profit/Revenue
=0.256/0.325
=0.78769231

Clene's gross margin of this year was 0.82608696. Clene's gross margin of last year was 0.78769231. ==> This year's gross margin is higher. ==> Score 1.

Question 9. Change in asset turnover

Compare this year's asset turnover (total sales for the year divided by total assets at the beginning of the year) to last year's asset turnover ratio.

Score 1 if this year's asset turnover ratio is higher, 0 if it's lower

Asset Turnover (This Year)=Revenue/Total Assets at the Beginning of This Year (Mar25)
=0.115/23.415
=0.00491138

Asset Turnover (Last Year)=Revenue/Total Assets at the Beginning of Last Year (Mar24)
=0.325/41.463
=0.00783831

Clene's asset turnover of this year was 0.00491138. Clene's asset turnover of last year was 0.00783831. ==> Last year's asset turnover is higher ==> Score 0.

Evaluation

Piotroski F-Score= Que. 1+ Que. 2+ Que. 3+Que. 4+Que. 5+Que. 6+Que. 7+Que. 8+Que. 9
=0+0+0+1+0+1+0+1+0
=3

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Clene has an F-score of 3. It is a bad or low score, which usually implies poor business operation.

Frequently Asked Questions Learn more about Piotroski F-Score →
What does a Piotroski F-Score of 3 mean?
Clene (FRA:84C0) has a Piotroski F-Score of 3 as of Jun. 28, 2026. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Clene and its competitors. This is near median its historical median of 3.00. Over the past decade, Clene's Piotroski F-Score has ranged from 1.00 to 4.00. According to the industry distribution chart, Clene ranks #1620 out of 1910 companies in the Consumer Packaged Goods industry, placing it in the top 84.8%.
Is Clene's Piotroski F-Score too high?
Clene's current Piotroski F-Score of 3 is near median its 10-year median of 3.00. Over the past 10 years, this metric has ranged from a low of 1.00 to a high of 4.00. The Consumer Packaged Goods industry median Piotroski F-Score is 5.00. Clene's value of 3 is 40% below this industry median. Based on the distribution chart, Clene ranks #1620 out of 1910 companies in the Consumer Packaged Goods industry, which is in the bottom quartile relative to peers. Overall, Clene has a GF Score™ of 33/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Clene's Piotroski F-Score compare to BHST and GWLL?
According to the Consumer Packaged Goods industry distribution chart, Clene ranks #1620 out of 1910 companies for Piotroski F-Score. This places Clene in the lower half of its industry. The industry median Piotroski F-Score is 5.00. Clene's value of 3 is 40% below this benchmark. Historically, Clene's own Piotroski F-Score has ranged from 1.00 to 4.00 over the past decade. While the company's 10-year median is 3.00 vs. the industry median of 5.00, Clene has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Piotroski F-Score for a Consumer Packaged Goods company?
The median Piotroski F-Score among Consumer Packaged Goods companies is 5.00, based on 1,910 companies in the industry. Companies in the top quartile (top 25%) have a Piotroski F-Score significantly above this median, while those in the bottom quartile fall well below. However, Piotroski F-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Clene's current Piotroski F-Score of 3 is 40% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Piotroski F-Score mean?
A high Piotroski F-Score can signal that a stock is expensive relative to its fundamentals. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Clene and its competitors. For the Consumer Packaged Goods industry, the median Piotroski F-Score is 5.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Clene's current Piotroski F-Score is 3, which is near median its own 10-year median of 3.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Clene stock overvalued right now?
Based on GuruFocus' analysis, Clene (FRA:84C0) is currently considered Significantly Overvalued. The stock's GF Value™ is €0.72, compared to a current price of €4.90 — trading 580.6% above its estimated fair value. The current Piotroski F-Score is 3, which is near median its 10-year median of 3.00 and 40% below the Consumer Packaged Goods industry median of 5.00. Clene's overall GF Score™ is 33/100 with 9 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Piotroski F-Score calculated?
Piotroski F-Score is calculated from a company's financial statements. For Clene (FRA:84C0), the current Piotroski F-Score is 3 as of Jun. 28, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Clene (FRA:84C0) Overvalued in 2026?

Based on GuruFocus' analysis, Clene stock appears to be overvalued. The current stock price of €4.90 is trading 580.6% above its estimated GF Value™ of €0.72. GuruFocus considers Clene to be Significantly Overvalued.

Key valuation signals for FRA:84C0:

  • Piotroski F-Score: 3 (near median its 10-year median of 3.00)
  • GF Value™: €0.72 vs. price of €4.90 (580.6% above fair value)
  • GF Score™: 33/100 with 9 warning signs
  • Industry Position: 40% below the Consumer Packaged Goods median (#1620 of 1910)

No single metric tells the full story. See the FRA:84C0 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Clene Business Description

Other Exchanges CLNN:USA
Address 6550 South Millrock Drive, Suite G50, Salt Lake City, UT, USA, 84121
Clene Inc is a clinical-stage pharmaceutical company pioneering the discovery, development, and commercialization of novel clean-surfaced nanotechnology (CSN) therapeutics. It is focused on the development of therapeutics for neurodegenerative diseases. It developed an electro-crystal-chemistry drug development platform that enables the production of concentrated, stable, clean-surfaced nanocrystal suspensions. It operates in one segment the development and commercialization of dietary supplements (Supplements). Products includes CNM-Au8, CNM-ZnA, CNM-AgZn17, rMetx, KHC46.
33GF Score

Get the complete analysis for FRA:84C0

Piotroski F-Score is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€4.90
Price
€0.72
GF Value