TYK Medicines (HKSE:02410) Piotroski F-Score: 3 (As of Aug. 01, 2026) — 40% Below Median

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HKSE:02410 TYK Medicines Inc HKSE:02410
7 GF Score
Price HK$6.81
! 3 Warning Signs
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What is TYK Medicines Piotroski F-Score?

TYK Medicines HKSE:02410 -4.08% 7 Piotroski F-Score is 3 as of Aug. 01, 2026, which is 40% below its 10-year median of 5.00. GuruFocus rates HKSE:02410 with a GF Score™ of 7/100. The stock has 3 warning signs investors should review. Among 1,329 Biotechnology companies, TYK Medicines ranks better than 54.7% on this metric.

Warning Sign:

Piotroski F-Score of 3 is low, which usually implies poor business operation.

The zones of discrimination were as such:

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

TYK Medicines has an F-score of 3. It is a bad or low score, which usually implies poor business operation.

The historical rank and industry rank for TYK Medicines's Piotroski F-Score or its related term are showing as below:

HKSE:02410' s Piotroski F-Score Range Over the Past 10 Years
Min: 3   Med: 5   Max: 7
Current: 3

During the past 4 years, the highest Piotroski F-Score of TYK Medicines was 7. The lowest was 3. And the median was 5.

TYK Medicines  (HKSE:02410) Piotroski F-Score Explanation

The developer of the system is Joseph D. Piotroski is relatively unknown accounting professor who shuns publicity and rarely gives interviews.

He graduated from the University of Illinois with a B.S. in accounting in 1989, received an M.B.A. from Indiana University in 1994. Five years later, in 1999, after earning a Ph.D. in accounting from the University of Michigan, he became an associate professor of accounting at the University of Chicago.

In 2000, he wrote a research paper called "Value Investing: The Use of Historical Financial Statement Information to Separate Winners from Losers" (pdf).

He wanted to see if he can develop a system (using a simple nine-point scoring system) that can increase the returns of a strategy of investing in low price to book (referred to in the paper as high book to market) value companies.

What he found was something that exceeded his most optimistic expectations.

Buying only those companies that scored highest (8 or 9) on his nine-point scale, or F-Score as he called it, over the 20 year period from 1976 to 1996 led to an average out-performance over the market of 13.4%.

Even more impressive were the results of a strategy of investing in the highest F-Score companies (8 or 9) and shorting companies with the lowest F-Score (0 or 1).

Over the same period from 1976 to 1996 (20 years) this strategy led to an average yearly return of 23%, substantially outperforming the average S&P 500 index return of 15.83% over the same period.


TYK Medicines Piotroski F-Score Related Terms


TYK Medicines Piotroski F-Score Historical Data

* Premium members only.

The historical data trend for TYK Medicines's Piotroski F-Score can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

TYK Medicines Piotroski F-Score Chart

TYK Medicines Annual Data
Trend Dec22 Dec23 Dec24 Dec25
Piotroski F-Score
N/A N/A 7.00 3.00

TYK Medicines Semi-Annual Data
Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Piotroski F-Score Get a 7-Day Free Trial N/A N/A 7.00 0.00 3.00

HKSE:02410 vs VRTX, REGN, RVMD: Piotroski F-Score Comparison

For the Biotechnology subindustry, TYK Medicines's Piotroski F-Score, along with its competitors' market caps and Piotroski F-Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


TYK Medicines Piotroski F-Score vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, TYK Medicines's Piotroski F-Score distribution charts can be found below:

* The bar in red indicates where TYK Medicines's Piotroski F-Score falls into.


HKSE:02410
7GF Score
TYK Medicines Inc HKSE:02410
Piotroski F-Score is just one metric. See GF Score™, valuation, warning signs, and more.
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How is the Piotroski F-Score calculated?

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

This Year (Dec25) TTM:Last Year (Dec24) TTM:
Net Income was HK$-331.16 Mil.
Cash Flow from Operations was HK$-238.36 Mil.
Revenue was HK$0.00 Mil.
Gross Profit was HK$0.00 Mil.
Average Total Assets from the begining of this year (Dec24)
to the end of this year (Dec25) was (977.66 + 861.395) / 2 = HK$919.5275 Mil.
Total Assets at the begining of this year (Dec24) was HK$977.66 Mil.
Long-Term Debt & Capital Lease Obligation was HK$4.25 Mil.
Total Current Assets was HK$487.23 Mil.
Total Current Liabilities was HK$340.01 Mil.
Net Income was HK$-413.14 Mil.

Revenue was HK$0.11 Mil.
Gross Profit was HK$0.02 Mil.
Average Total Assets from the begining of last year (Dec23)
to the end of last year (Dec24) was (626.886 + 977.66) / 2 = HK$802.273 Mil.
Total Assets at the begining of last year (Dec23) was HK$626.89 Mil.
Long-Term Debt & Capital Lease Obligation was HK$6.92 Mil.
Total Current Assets was HK$607.48 Mil.
Total Current Liabilities was HK$308.64 Mil.

*Note: If the latest quarterly/semi-annual/annual total assets data is 0, then we will use previous quarterly/semi-annual/annual data for all the items in the balance sheet.

Profitability

Question 1. Return on Assets (ROA)

Net income before extraordinary items for the year divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

TYK Medicines's current Net Income (TTM) was -331.16. ==> Negative ==> Score 0.

Question 2. Cash Flow Return on Assets (CFROA)

Net cash flow from operating activities (operating cash flow) divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

TYK Medicines's current Cash Flow from Operations (TTM) was -238.36. ==> Negative ==> Score 0.

Question 3. Change in Return on Assets

Compare this year's return on assets (1) to last year's return on assets.

Score 1 if it's higher, 0 if it's lower.

ROA (This Year)=Net Income/Total Assets (Dec24)
=-331.161/977.66
=-0.33872819

ROA (Last Year)=Net Income/Total Assets (Dec23)
=-413.141/626.886
=-0.65903689

TYK Medicines's return on assets of this year was -0.33872819. TYK Medicines's return on assets of last year was -0.65903689. ==> This year is higher. ==> Score 1.

Question 4. Quality of Earnings (Accrual)

Compare Cash flow return on assets (2) to return on assets (1)

Score 1 if CFROA > ROA, 0 if CFROA <= ROA.

TYK Medicines's current Net Income (TTM) was -331.16. TYK Medicines's current Cash Flow from Operations (TTM) was -238.36. ==> -238.36 > -331.16 ==> CFROA > ROA ==> Score 1.

Funding

Question 5. Change in Gearing or Leverage

Compare this year's gearing (long-term debt divided by average total assets) to last year's gearing.

Score 0 if this year's gearing is higher, 1 otherwise.

Gearing (This Year: Dec25)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Dec24 to Dec25
=4.25/919.5275
=0.00462194

Gearing (Last Year: Dec24)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Dec23 to Dec24
=6.924/802.273
=0.00863048

TYK Medicines's gearing of this year was 0.00462194. TYK Medicines's gearing of last year was 0.00863048. ==> This year is lower or equal to last year. ==> Score 1.

Question 6. Change in Working Capital (Liquidity)

Compare this year's current ratio (current assets divided by current liabilities) to last year's current ratio.

Score 1 if this year's current ratio is higher, 0 if it's lower

Current Ratio (This Year: Dec25)=Total Current Assets/Total Current Liabilities
=487.229/340.005
=1.4330054

Current Ratio (Last Year: Dec24)=Total Current Assets/Total Current Liabilities
=607.479/308.644
=1.96821905

TYK Medicines's current ratio of this year was 1.4330054. TYK Medicines's current ratio of last year was 1.96821905. ==> Last year's current ratio is higher ==> Score 0.

Question 7. Change in Shares in Issue

Compare the number of shares in issue this year, to the number in issue last year.

Score 0 if there is larger number of shares in issue this year, 1 otherwise.

TYK Medicines's number of shares in issue this year was 374.539. TYK Medicines's number of shares in issue last year was 337.616. ==> There is larger number of shares in issue this year. ==> Score 0.

Efficiency

Question 8. Change in Gross Margin

Compare this year's gross margin (Gross Profit divided by sales) to last year's.

Score 1 if this year's gross margin is higher, 0 if it's lower.

Gross Margin (This Year: TTM)=Gross Profit/Revenue
=0/0
=

Gross Margin (Last Year: TTM)=Gross Profit/Revenue
=0.015/0.114
=0.13157895

TYK Medicines's gross margin of this year was . TYK Medicines's gross margin of last year was 0.13157895. ==> Last year's gross margin is higher ==> Score 0.

Question 9. Change in asset turnover

Compare this year's asset turnover (total sales for the year divided by total assets at the beginning of the year) to last year's asset turnover ratio.

Score 1 if this year's asset turnover ratio is higher, 0 if it's lower

Asset Turnover (This Year)=Revenue/Total Assets at the Beginning of This Year (Dec24)
=0/977.66
=0

Asset Turnover (Last Year)=Revenue/Total Assets at the Beginning of Last Year (Dec23)
=0.114/626.886
=0.00018185

TYK Medicines's asset turnover of this year was 0. TYK Medicines's asset turnover of last year was 0.00018185. ==> Last year's asset turnover is higher ==> Score 0.

Evaluation

Piotroski F-Score= Que. 1+ Que. 2+ Que. 3+Que. 4+Que. 5+Que. 6+Que. 7+Que. 8+Que. 9
=0+0+1+1+1+0+0+0+0
=3

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

TYK Medicines has an F-score of 3. It is a bad or low score, which usually implies poor business operation.

Frequently Asked Questions Learn more about Piotroski F-Score →
What does a Piotroski F-Score of 3 mean?
TYK Medicines (HKSE:02410) has a Piotroski F-Score of 3 as of Aug. 01, 2026. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on TYK Medicines and its competitors. This is 40% below median its historical median of 5.00. Over the past decade, TYK Medicines' Piotroski F-Score has ranged from 3.00 to 7.00. According to the industry distribution chart, TYK Medicines ranks #602 out of 1329 companies in the Biotechnology industry, placing it in the top 45.3%.
Is TYK Medicines' Piotroski F-Score too high?
TYK Medicines' current Piotroski F-Score of 3 is 40% below median its 10-year median of 5.00. Over the past 10 years, this metric has ranged from a low of 3.00 to a high of 7.00. The Biotechnology industry median Piotroski F-Score is 3.00. TYK Medicines' value of 3 is 0% at this industry median. Based on the distribution chart, TYK Medicines ranks #602 out of 1329 companies in the Biotechnology industry, which is above the industry midpoint. Overall, TYK Medicines has a GF Score™ of 7/100, reflecting its overall financial health beyond just this single metric.
How does TYK Medicines' Piotroski F-Score compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, TYK Medicines ranks #602 out of 1329 companies for Piotroski F-Score. This puts TYK Medicines in the upper half of its industry. The industry median Piotroski F-Score is 3.00. TYK Medicines' value of 3 is 0% at this benchmark. Historically, TYK Medicines' own Piotroski F-Score has ranged from 3.00 to 7.00 over the past decade. While the company's 10-year median is 5.00 vs. the industry median of 3.00, TYK Medicines has consistently been at the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Piotroski F-Score for a Biotechnology company?
The median Piotroski F-Score among Biotechnology companies is 3.00, based on 1,329 companies in the industry. Companies in the top quartile (top 25%) have a Piotroski F-Score significantly above this median, while those in the bottom quartile fall well below. However, Piotroski F-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. TYK Medicines's current Piotroski F-Score of 3 is 0% at the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Piotroski F-Score mean?
A high Piotroski F-Score can signal that a stock is expensive relative to its fundamentals. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on TYK Medicines and its competitors. For the Biotechnology industry, the median Piotroski F-Score is 3.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. TYK Medicines's current Piotroski F-Score is 3, which is 40% below median its own 10-year median of 5.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is TYK Medicines stock overvalued right now?
TYK Medicines (HKSE:02410) has a current Piotroski F-Score of 3. The current Piotroski F-Score is 3, which is 40% below median its 10-year median of 5.00 and 0% at the Biotechnology industry median of 3.00. TYK Medicines' overall GF Score™ is 7/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Piotroski F-Score calculated?
Piotroski F-Score is calculated from a company's financial statements. For TYK Medicines (HKSE:02410), the current Piotroski F-Score is 3 as of Aug. 01, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

TYK Medicines Business Description

Address No.277 Longlan Road, 8th Floor, Building T2, China Eastern Binjiang Center, Xuhui District, Shanghai, CHN
TYK Medicines Inc is a clinical-stage biopharmaceutical company. The company is engaged in drug discovery research and development. The company and its subsidiaries are principally engaged in the research, development, and commercialization of pharmaceutical products. The company has built a pipeline with10 drug candidates, including Core Product TY-9591, five clinical stage products, and four preclinical stage or early clinical development stage.
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Piotroski F-Score is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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