Cloudbreak Pharma (HKSE:02592) Piotroski F-Score: 4 (As of Aug. 10, 2026) — 20% Below Median

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HKSE:02592 Cloudbreak Pharma Inc HKSE:02592
11 GF Score
Price HK$1.20
! 2 Warning Signs
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What is Cloudbreak Pharma Piotroski F-Score?

Cloudbreak Pharma HKSE:02592 -1.64% 11 Piotroski F-Score is 4 as of Aug. 10, 2026, which is 20% below its 10-year median of 5.00. GuruFocus rates HKSE:02592 with a GF Score™ of 11/100. The stock has 2 warning signs investors should review. Among 1,325 Biotechnology companies, Cloudbreak Pharma ranks better than 74.04% on this metric.

The zones of discrimination were as such:

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Cloudbreak Pharma has an F-score of 4 indicating the company's financial situation is typical for a stable company.

The historical rank and industry rank for Cloudbreak Pharma's Piotroski F-Score or its related term are showing as below:

HKSE:02592' s Piotroski F-Score Range Over the Past 10 Years
Min: 4   Med: 5   Max: 5
Current: 4

During the past 4 years, the highest Piotroski F-Score of Cloudbreak Pharma was 5. The lowest was 4. And the median was 5.

Cloudbreak Pharma  (HKSE:02592) Piotroski F-Score Explanation

The developer of the system is Joseph D. Piotroski is relatively unknown accounting professor who shuns publicity and rarely gives interviews.

He graduated from the University of Illinois with a B.S. in accounting in 1989, received an M.B.A. from Indiana University in 1994. Five years later, in 1999, after earning a Ph.D. in accounting from the University of Michigan, he became an associate professor of accounting at the University of Chicago.

In 2000, he wrote a research paper called "Value Investing: The Use of Historical Financial Statement Information to Separate Winners from Losers" (pdf).

He wanted to see if he can develop a system (using a simple nine-point scoring system) that can increase the returns of a strategy of investing in low price to book (referred to in the paper as high book to market) value companies.

What he found was something that exceeded his most optimistic expectations.

Buying only those companies that scored highest (8 or 9) on his nine-point scale, or F-Score as he called it, over the 20 year period from 1976 to 1996 led to an average out-performance over the market of 13.4%.

Even more impressive were the results of a strategy of investing in the highest F-Score companies (8 or 9) and shorting companies with the lowest F-Score (0 or 1).

Over the same period from 1976 to 1996 (20 years) this strategy led to an average yearly return of 23%, substantially outperforming the average S&P 500 index return of 15.83% over the same period.


Cloudbreak Pharma Piotroski F-Score Related Terms


Cloudbreak Pharma Piotroski F-Score Historical Data

* Premium members only.

The historical data trend for Cloudbreak Pharma's Piotroski F-Score can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Cloudbreak Pharma Piotroski F-Score Chart

Cloudbreak Pharma Annual Data
Trend Dec22 Dec23 Dec24 Dec25
Piotroski F-Score
N/A N/A 5.00 4.00

Cloudbreak Pharma Semi-Annual Data
Dec22 Dec23 Jun24 Dec24 Jun25 Dec25
Piotroski F-Score Get a 7-Day Free Trial N/A 0.00 5.00 0.00 4.00

HKSE:02592 vs VRTX, REGN, RVMD: Piotroski F-Score Comparison

For the Biotechnology subindustry, Cloudbreak Pharma's Piotroski F-Score, along with its competitors' market caps and Piotroski F-Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Cloudbreak Pharma Piotroski F-Score vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Cloudbreak Pharma's Piotroski F-Score distribution charts can be found below:

* The bar in red indicates where Cloudbreak Pharma's Piotroski F-Score falls into.


HKSE:02592
11GF Score
Cloudbreak Pharma Inc HKSE:02592
Piotroski F-Score is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

How is the Piotroski F-Score calculated?

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

This Year (Dec25) TTM:Last Year (Dec24) TTM:
Net Income was HK$-526.45 Mil.
Cash Flow from Operations was HK$-401.02 Mil.
Revenue was HK$0.00 Mil.
Gross Profit was HK$0.00 Mil.
Average Total Assets from the begining of this year (Dec24)
to the end of this year (Dec25) was (311.006 + 518.264) / 2 = HK$414.635 Mil.
Total Assets at the begining of this year (Dec24) was HK$311.01 Mil.
Long-Term Debt & Capital Lease Obligation was HK$0.76 Mil.
Total Current Assets was HK$500.62 Mil.
Total Current Liabilities was HK$46.86 Mil.
Net Income was HK$-770.58 Mil.

Revenue was HK$77.73 Mil.
Gross Profit was HK$77.73 Mil.
Average Total Assets from the begining of last year (Dec23)
to the end of last year (Dec24) was (506.317 + 311.006) / 2 = HK$408.6615 Mil.
Total Assets at the begining of last year (Dec23) was HK$506.32 Mil.
Long-Term Debt & Capital Lease Obligation was HK$1.63 Mil.
Total Current Assets was HK$291.57 Mil.
Total Current Liabilities was HK$3,042.09 Mil.

*Note: If the latest quarterly/semi-annual/annual total assets data is 0, then we will use previous quarterly/semi-annual/annual data for all the items in the balance sheet.

Profitability

Question 1. Return on Assets (ROA)

Net income before extraordinary items for the year divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Cloudbreak Pharma's current Net Income (TTM) was -526.45. ==> Negative ==> Score 0.

Question 2. Cash Flow Return on Assets (CFROA)

Net cash flow from operating activities (operating cash flow) divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Cloudbreak Pharma's current Cash Flow from Operations (TTM) was -401.02. ==> Negative ==> Score 0.

Question 3. Change in Return on Assets

Compare this year's return on assets (1) to last year's return on assets.

Score 1 if it's higher, 0 if it's lower.

ROA (This Year)=Net Income/Total Assets (Dec24)
=-526.449/311.006
=-1.6927294

ROA (Last Year)=Net Income/Total Assets (Dec23)
=-770.577/506.317
=-1.52192599

Cloudbreak Pharma's return on assets of this year was -1.6927294. Cloudbreak Pharma's return on assets of last year was -1.52192599. ==> Last year is higher ==> Score 0.

Question 4. Quality of Earnings (Accrual)

Compare Cash flow return on assets (2) to return on assets (1)

Score 1 if CFROA > ROA, 0 if CFROA <= ROA.

Cloudbreak Pharma's current Net Income (TTM) was -526.45. Cloudbreak Pharma's current Cash Flow from Operations (TTM) was -401.02. ==> -401.02 > -526.45 ==> CFROA > ROA ==> Score 1.

Funding

Question 5. Change in Gearing or Leverage

Compare this year's gearing (long-term debt divided by average total assets) to last year's gearing.

Score 0 if this year's gearing is higher, 1 otherwise.

Gearing (This Year: Dec25)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Dec24 to Dec25
=0.763/414.635
=0.00184017

Gearing (Last Year: Dec24)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Dec23 to Dec24
=1.625/408.6615
=0.0039764

Cloudbreak Pharma's gearing of this year was 0.00184017. Cloudbreak Pharma's gearing of last year was 0.0039764. ==> This year is lower or equal to last year. ==> Score 1.

Question 6. Change in Working Capital (Liquidity)

Compare this year's current ratio (current assets divided by current liabilities) to last year's current ratio.

Score 1 if this year's current ratio is higher, 0 if it's lower

Current Ratio (This Year: Dec25)=Total Current Assets/Total Current Liabilities
=500.617/46.856
=10.68415998

Current Ratio (Last Year: Dec24)=Total Current Assets/Total Current Liabilities
=291.572/3042.089
=0.09584598

Cloudbreak Pharma's current ratio of this year was 10.68415998. Cloudbreak Pharma's current ratio of last year was 0.09584598. ==> This year's current ratio is higher. ==> Score 1.

Question 7. Change in Shares in Issue

Compare the number of shares in issue this year, to the number in issue last year.

Score 0 if there is larger number of shares in issue this year, 1 otherwise.

Cloudbreak Pharma's number of shares in issue this year was 656.741. Cloudbreak Pharma's number of shares in issue last year was 838.893. ==> There is smaller number of shares in issue this year, or the same. ==> Score 1.

Efficiency

Question 8. Change in Gross Margin

Compare this year's gross margin (Gross Profit divided by sales) to last year's.

Score 1 if this year's gross margin is higher, 0 if it's lower.

Gross Margin (This Year: TTM)=Gross Profit/Revenue
=0/0
=

Gross Margin (Last Year: TTM)=Gross Profit/Revenue
=77.734/77.734
=1

Cloudbreak Pharma's gross margin of this year was . Cloudbreak Pharma's gross margin of last year was 1. ==> Last year's gross margin is higher ==> Score 0.

Question 9. Change in asset turnover

Compare this year's asset turnover (total sales for the year divided by total assets at the beginning of the year) to last year's asset turnover ratio.

Score 1 if this year's asset turnover ratio is higher, 0 if it's lower

Asset Turnover (This Year)=Revenue/Total Assets at the Beginning of This Year (Dec24)
=0/311.006
=0

Asset Turnover (Last Year)=Revenue/Total Assets at the Beginning of Last Year (Dec23)
=77.734/506.317
=0.15352832

Cloudbreak Pharma's asset turnover of this year was 0. Cloudbreak Pharma's asset turnover of last year was 0.15352832. ==> Last year's asset turnover is higher ==> Score 0.

Evaluation

Piotroski F-Score= Que. 1+ Que. 2+ Que. 3+Que. 4+Que. 5+Que. 6+Que. 7+Que. 8+Que. 9
=0+0+0+1+1+1+1+0+0
=4

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Cloudbreak Pharma has an F-score of 4 indicating the company's financial situation is typical for a stable company.

Frequently Asked Questions Learn more about Piotroski F-Score →
What does a Piotroski F-Score of 4 mean?
Cloudbreak Pharma (HKSE:02592) has a Piotroski F-Score of 4 as of Aug. 10, 2026. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Cloudbreak Pharma and its competitors. This is 20% below median its historical median of 5.00. Over the past decade, Cloudbreak Pharma's Piotroski F-Score has ranged from 4.00 to 5.00. According to the industry distribution chart, Cloudbreak Pharma ranks #344 out of 1325 companies in the Biotechnology industry, placing it in the top 26%.
Is Cloudbreak Pharma's Piotroski F-Score too high?
Cloudbreak Pharma's current Piotroski F-Score of 4 is 20% below median its 10-year median of 5.00. Over the past 10 years, this metric has ranged from a low of 4.00 to a high of 5.00. The Biotechnology industry median Piotroski F-Score is 3.00. Cloudbreak Pharma's value of 4 is 33.3% above this industry median. Based on the distribution chart, Cloudbreak Pharma ranks #344 out of 1325 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Cloudbreak Pharma has a GF Score™ of 11/100, reflecting its overall financial health beyond just this single metric.
How does Cloudbreak Pharma's Piotroski F-Score compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Cloudbreak Pharma ranks #344 out of 1325 companies for Piotroski F-Score. This puts Cloudbreak Pharma in the upper half of its industry. The industry median Piotroski F-Score is 3.00. Cloudbreak Pharma's value of 4 is 33.3% above this benchmark. Historically, Cloudbreak Pharma's own Piotroski F-Score has ranged from 4.00 to 5.00 over the past decade. While the company's 10-year median is 5.00 vs. the industry median of 3.00, Cloudbreak Pharma has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Piotroski F-Score for a Biotechnology company?
The median Piotroski F-Score among Biotechnology companies is 3.00, based on 1,325 companies in the industry. Companies in the top quartile (top 25%) have a Piotroski F-Score significantly above this median, while those in the bottom quartile fall well below. However, Piotroski F-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Cloudbreak Pharma's current Piotroski F-Score of 4 is 33.3% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Piotroski F-Score mean?
A high Piotroski F-Score can signal that a stock is expensive relative to its fundamentals. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Cloudbreak Pharma and its competitors. For the Biotechnology industry, the median Piotroski F-Score is 3.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Cloudbreak Pharma's current Piotroski F-Score is 4, which is 20% below median its own 10-year median of 5.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Cloudbreak Pharma stock overvalued right now?
Cloudbreak Pharma (HKSE:02592) has a current Piotroski F-Score of 4. The current Piotroski F-Score is 4, which is 20% below median its 10-year median of 5.00 and 33.3% above the Biotechnology industry median of 3.00. Cloudbreak Pharma's overall GF Score™ is 11/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Piotroski F-Score calculated?
Piotroski F-Score is calculated from a company's financial statements. For Cloudbreak Pharma (HKSE:02592), the current Piotroski F-Score is 4 as of Aug. 10, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Cloudbreak Pharma Business Description

Address 8921 Research Drive, Irvine, CA, USA, 92618
Cloudbreak Pharma Inc is engaged in research and development of ophthalmology biotechnology. The company is a clinical-stage ophthalmology biotechnology company focused on developing treatments for ophthalmic diseases through the proprietary drug discovery and development capabilities, with operations based in the United States and China. The pipeline currently consists of nine drug candidates targeted for treatment of anterior and posterior ophthalmic diseases, including five clinical-stage and four pre-clinical stage candidates. The drugs in the pipeline include CBT-001, CBT-004, CBT-009, and CBT-199.
11GF Score

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