AP Biosciences (ROCO:6945) Piotroski F-Score: 3 (As of Jul. 12, 2026) — Near Median


ROCO:6945 AP Biosciences Inc ROCO:6945
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What is AP Biosciences Piotroski F-Score?

AP Biosciences ROCO:6945 14 Piotroski F-Score is 3 as of Jul. 12, 2026, which is at its 10-year median of 3.00. GuruFocus rates ROCO:6945 with a GF Score™ of 14/100. The stock has 1 warning sign investors should review. Among 1,333 Biotechnology companies, AP Biosciences ranks better than 54.69% on this metric.

Warning Sign:

Piotroski F-Score of 3 is low, which usually implies poor business operation.

The zones of discrimination were as such:

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

AP Biosciences has an F-score of 3. It is a bad or low score, which usually implies poor business operation.

The historical rank and industry rank for AP Biosciences's Piotroski F-Score or its related term are showing as below:

ROCO:6945' s Piotroski F-Score Range Over the Past 10 Years
Min: 3   Med: 3   Max: 4
Current: 3

During the past 6 years, the highest Piotroski F-Score of AP Biosciences was 4. The lowest was 3. And the median was 3.

AP Biosciences  (ROCO:6945) Piotroski F-Score Explanation

The developer of the system is Joseph D. Piotroski is relatively unknown accounting professor who shuns publicity and rarely gives interviews.

He graduated from the University of Illinois with a B.S. in accounting in 1989, received an M.B.A. from Indiana University in 1994. Five years later, in 1999, after earning a Ph.D. in accounting from the University of Michigan, he became an associate professor of accounting at the University of Chicago.

In 2000, he wrote a research paper called "Value Investing: The Use of Historical Financial Statement Information to Separate Winners from Losers" (pdf).

He wanted to see if he can develop a system (using a simple nine-point scoring system) that can increase the returns of a strategy of investing in low price to book (referred to in the paper as high book to market) value companies.

What he found was something that exceeded his most optimistic expectations.

Buying only those companies that scored highest (8 or 9) on his nine-point scale, or F-Score as he called it, over the 20 year period from 1976 to 1996 led to an average out-performance over the market of 13.4%.

Even more impressive were the results of a strategy of investing in the highest F-Score companies (8 or 9) and shorting companies with the lowest F-Score (0 or 1).

Over the same period from 1976 to 1996 (20 years) this strategy led to an average yearly return of 23%, substantially outperforming the average S&P 500 index return of 15.83% over the same period.


AP Biosciences Piotroski F-Score Related Terms


AP Biosciences Piotroski F-Score Historical Data

* Premium members only.

The historical data trend for AP Biosciences's Piotroski F-Score can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

AP Biosciences Piotroski F-Score Chart

AP Biosciences Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Piotroski F-Score
Get a 7-Day Free Trial N/A 4.00 3.00 3.00 3.00

AP Biosciences Quarterly Data
Dec20 Dec21 Dec22 Jun23 Dec23 Jun24 Sep24 Dec24 Jun25 Sep25 Dec25
Piotroski F-Score Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only 0.00 3.00 0.00 0.00 3.00

ROCO:6945 vs VRTX, REGN, ALNY: Piotroski F-Score Comparison

For the Biotechnology subindustry, AP Biosciences's Piotroski F-Score, along with its competitors' market caps and Piotroski F-Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


AP Biosciences Piotroski F-Score vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, AP Biosciences's Piotroski F-Score distribution charts can be found below:

* The bar in red indicates where AP Biosciences's Piotroski F-Score falls into.


ROCO:6945
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AP Biosciences Inc ROCO:6945
Piotroski F-Score is just one metric. See GF Score™, valuation, warning signs, and more.
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How is the Piotroski F-Score calculated?

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

This Year (Dec25) TTM:Last Year (Dec24) TTM:
Net Income was NT$-444.77 Mil.
Cash Flow from Operations was NT$-352.09 Mil.
Revenue was NT$0.00 Mil.
Gross Profit was NT$0.00 Mil.
Average Total Assets from the begining of this year (Dec24)
to the end of this year (Dec25) was (1727.138 + 1365.33) / 2 = NT$1546.234 Mil.
Total Assets at the begining of this year (Dec24) was NT$1,727.14 Mil.
Long-Term Debt & Capital Lease Obligation was NT$47.86 Mil.
Total Current Assets was NT$1,221.59 Mil.
Total Current Liabilities was NT$40.80 Mil.
Net Income was NT$-422.75 Mil.

Revenue was NT$0.00 Mil.
Gross Profit was NT$0.00 Mil.
Average Total Assets from the begining of last year (Dec23)
to the end of last year (Dec24) was (890.756 + 1727.138) / 2 = NT$1308.947 Mil.
Total Assets at the begining of last year (Dec23) was NT$890.76 Mil.
Long-Term Debt & Capital Lease Obligation was NT$59.26 Mil.
Total Current Assets was NT$1,581.45 Mil.
Total Current Liabilities was NT$39.67 Mil.

*Note: If the latest quarterly/semi-annual/annual total assets data is 0, then we will use previous quarterly/semi-annual/annual data for all the items in the balance sheet.

Profitability

Question 1. Return on Assets (ROA)

Net income before extraordinary items for the year divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

AP Biosciences's current Net Income (TTM) was -444.77. ==> Negative ==> Score 0.

Question 2. Cash Flow Return on Assets (CFROA)

Net cash flow from operating activities (operating cash flow) divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

AP Biosciences's current Cash Flow from Operations (TTM) was -352.09. ==> Negative ==> Score 0.

Question 3. Change in Return on Assets

Compare this year's return on assets (1) to last year's return on assets.

Score 1 if it's higher, 0 if it's lower.

ROA (This Year)=Net Income/Total Assets (Dec24)
=-444.767/1727.138
=-0.25751677

ROA (Last Year)=Net Income/Total Assets (Dec23)
=-422.746/890.756
=-0.47459237

AP Biosciences's return on assets of this year was -0.25751677. AP Biosciences's return on assets of last year was -0.47459237. ==> This year is higher. ==> Score 1.

Question 4. Quality of Earnings (Accrual)

Compare Cash flow return on assets (2) to return on assets (1)

Score 1 if CFROA > ROA, 0 if CFROA <= ROA.

AP Biosciences's current Net Income (TTM) was -444.77. AP Biosciences's current Cash Flow from Operations (TTM) was -352.09. ==> -352.09 > -444.77 ==> CFROA > ROA ==> Score 1.

Funding

Question 5. Change in Gearing or Leverage

Compare this year's gearing (long-term debt divided by average total assets) to last year's gearing.

Score 0 if this year's gearing is higher, 1 otherwise.

Gearing (This Year: Dec25)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Dec24 to Dec25
=47.859/1546.234
=0.03095198

Gearing (Last Year: Dec24)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Dec23 to Dec24
=59.256/1308.947
=0.04526998

AP Biosciences's gearing of this year was 0.03095198. AP Biosciences's gearing of last year was 0.04526998. ==> This year is lower or equal to last year. ==> Score 1.

Question 6. Change in Working Capital (Liquidity)

Compare this year's current ratio (current assets divided by current liabilities) to last year's current ratio.

Score 1 if this year's current ratio is higher, 0 if it's lower

Current Ratio (This Year: Dec25)=Total Current Assets/Total Current Liabilities
=1221.591/40.798
=29.94242365

Current Ratio (Last Year: Dec24)=Total Current Assets/Total Current Liabilities
=1581.454/39.67
=39.86523822

AP Biosciences's current ratio of this year was 29.94242365. AP Biosciences's current ratio of last year was 39.86523822. ==> Last year's current ratio is higher ==> Score 0.

Question 7. Change in Shares in Issue

Compare the number of shares in issue this year, to the number in issue last year.

Score 0 if there is larger number of shares in issue this year, 1 otherwise.

AP Biosciences's number of shares in issue this year was 85.121. AP Biosciences's number of shares in issue last year was 75.29. ==> There is larger number of shares in issue this year. ==> Score 0.

Efficiency

Question 8. Change in Gross Margin

Compare this year's gross margin (Gross Profit divided by sales) to last year's.

Score 1 if this year's gross margin is higher, 0 if it's lower.

Gross Margin (This Year: TTM)=Gross Profit/Revenue
=0/0
=

Gross Margin (Last Year: TTM)=Gross Profit/Revenue
=0/0
=

AP Biosciences's gross margin of this year was . AP Biosciences's gross margin of last year was . ==> Last year's gross margin is higher ==> Score 0.

Question 9. Change in asset turnover

Compare this year's asset turnover (total sales for the year divided by total assets at the beginning of the year) to last year's asset turnover ratio.

Score 1 if this year's asset turnover ratio is higher, 0 if it's lower

Asset Turnover (This Year)=Revenue/Total Assets at the Beginning of This Year (Dec24)
=0/1727.138
=0

Asset Turnover (Last Year)=Revenue/Total Assets at the Beginning of Last Year (Dec23)
=0/890.756
=0

AP Biosciences's asset turnover of this year was 0. AP Biosciences's asset turnover of last year was 0. ==> Last year's asset turnover is higher ==> Score 0.

Evaluation

Piotroski F-Score= Que. 1+ Que. 2+ Que. 3+Que. 4+Que. 5+Que. 6+Que. 7+Que. 8+Que. 9
=0+0+1+1+1+0+0+0+0
=3

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

AP Biosciences has an F-score of 3. It is a bad or low score, which usually implies poor business operation.

Frequently Asked Questions Learn more about Piotroski F-Score →
What does a Piotroski F-Score of 3 mean?
AP Biosciences (ROCO:6945) has a Piotroski F-Score of 3 as of Jul. 12, 2026. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on AP Biosciences and its competitors. This is near median its historical median of 3.00. Over the past decade, AP Biosciences' Piotroski F-Score has ranged from 3.00 to 4.00. According to the industry distribution chart, AP Biosciences ranks #604 out of 1333 companies in the Biotechnology industry, placing it in the top 45.3%.
Is AP Biosciences' Piotroski F-Score too high?
AP Biosciences' current Piotroski F-Score of 3 is near median its 10-year median of 3.00. Over the past 10 years, this metric has ranged from a low of 3.00 to a high of 4.00. The Biotechnology industry median Piotroski F-Score is 3.00. AP Biosciences' value of 3 is 0% at this industry median. Based on the distribution chart, AP Biosciences ranks #604 out of 1333 companies in the Biotechnology industry, which is above the industry midpoint. Overall, AP Biosciences has a GF Score™ of 14/100, reflecting its overall financial health beyond just this single metric.
How does AP Biosciences' Piotroski F-Score compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, AP Biosciences ranks #604 out of 1333 companies for Piotroski F-Score. This puts AP Biosciences in the upper half of its industry. The industry median Piotroski F-Score is 3.00. AP Biosciences' value of 3 is 0% at this benchmark. Historically, AP Biosciences' own Piotroski F-Score has ranged from 3.00 to 4.00 over the past decade. While the company's 10-year median is 3.00 vs. the industry median of 3.00, AP Biosciences has consistently been at the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Piotroski F-Score for a Biotechnology company?
The median Piotroski F-Score among Biotechnology companies is 3.00, based on 1,333 companies in the industry. Companies in the top quartile (top 25%) have a Piotroski F-Score significantly above this median, while those in the bottom quartile fall well below. However, Piotroski F-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. AP Biosciences's current Piotroski F-Score of 3 is 0% at the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Piotroski F-Score mean?
A high Piotroski F-Score can signal that a stock is expensive relative to its fundamentals. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on AP Biosciences and its competitors. For the Biotechnology industry, the median Piotroski F-Score is 3.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. AP Biosciences's current Piotroski F-Score is 3, which is near median its own 10-year median of 3.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is AP Biosciences stock overvalued right now?
AP Biosciences (ROCO:6945) has a current Piotroski F-Score of 3. The current Piotroski F-Score is 3, which is near median its 10-year median of 3.00 and 0% at the Biotechnology industry median of 3.00. AP Biosciences' overall GF Score™ is 14/100 with 1 warning sign to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Piotroski F-Score calculated?
Piotroski F-Score is calculated from a company's financial statements. For AP Biosciences (ROCO:6945), the current Piotroski F-Score is 3 as of Jul. 12, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

AP Biosciences Business Description

Address No. 3, Park Street, 17th Floor, Taipei, TWN
AP Biosciences Inc is a clinical-stage bispecific antibody new drug research and development company. It has developed a series of antibody and protein lead drugs through a self-designed technology platform for unmet medical needs, focusing on Specific targets associated with diseases to deliver safe, effective and cost-effective medicines.
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