Energenesis Biomedical Co (TPE:6657) Piotroski F-Score: 4 (As of Jun. 28, 2026) — Near Median


TPE:6657 Energenesis Biomedical Co Ltd TPE:6657
64 GF Score
Price NT$34.90
GF Value NT$51.28
Valuation Possible Value Trap
! 3 Warning Signs
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What is Energenesis Biomedical Co Piotroski F-Score?

Energenesis Biomedical Co TPE:6657 -2.92% 64 Piotroski F-Score is 4 as of Jun. 28, 2026, which is at its 10-year median of 4.00. GuruFocus rates TPE:6657 with a GF Score™ of 64/100 and a GF Value™ of NT$51.28 (Possible Value Trap). The stock has 3 warning signs investors should review. Among 1,340 Biotechnology companies, Energenesis Biomedical Co ranks better than 74.18% on this metric.

The zones of discrimination were as such:

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Energenesis Biomedical Co has an F-score of 4 indicating the company's financial situation is typical for a stable company.

The historical rank and industry rank for Energenesis Biomedical Co's Piotroski F-Score or its related term are showing as below:

TPE:6657' s Piotroski F-Score Range Over the Past 10 Years
Min: 1   Med: 4   Max: 5
Current: 4

During the past 11 years, the highest Piotroski F-Score of Energenesis Biomedical Co was 5. The lowest was 1. And the median was 4.

Energenesis Biomedical Co  (TPE:6657) Piotroski F-Score Explanation

The developer of the system is Joseph D. Piotroski is relatively unknown accounting professor who shuns publicity and rarely gives interviews.

He graduated from the University of Illinois with a B.S. in accounting in 1989, received an M.B.A. from Indiana University in 1994. Five years later, in 1999, after earning a Ph.D. in accounting from the University of Michigan, he became an associate professor of accounting at the University of Chicago.

In 2000, he wrote a research paper called "Value Investing: The Use of Historical Financial Statement Information to Separate Winners from Losers" (pdf).

He wanted to see if he can develop a system (using a simple nine-point scoring system) that can increase the returns of a strategy of investing in low price to book (referred to in the paper as high book to market) value companies.

What he found was something that exceeded his most optimistic expectations.

Buying only those companies that scored highest (8 or 9) on his nine-point scale, or F-Score as he called it, over the 20 year period from 1976 to 1996 led to an average out-performance over the market of 13.4%.

Even more impressive were the results of a strategy of investing in the highest F-Score companies (8 or 9) and shorting companies with the lowest F-Score (0 or 1).

Over the same period from 1976 to 1996 (20 years) this strategy led to an average yearly return of 23%, substantially outperforming the average S&P 500 index return of 15.83% over the same period.


Energenesis Biomedical Co Piotroski F-Score Related Terms


Energenesis Biomedical Co Piotroski F-Score Historical Data

* Premium members only.

The historical data trend for Energenesis Biomedical Co's Piotroski F-Score can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Energenesis Biomedical Co Piotroski F-Score Chart

Energenesis Biomedical Co Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Piotroski F-Score
Get a 7-Day Free Trial Premium Member Only Premium Member Only 4.00 4.00 5.00 3.00 4.00

Energenesis Biomedical Co Quarterly Data
Dec20 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
Piotroski F-Score Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 3.00 4.00 4.00 4.00 4.00

TPE:6657 vs VRTX, REGN, ALNY: Piotroski F-Score Comparison

For the Biotechnology subindustry, Energenesis Biomedical Co's Piotroski F-Score, along with its competitors' market caps and Piotroski F-Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Energenesis Biomedical Co Piotroski F-Score vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Energenesis Biomedical Co's Piotroski F-Score distribution charts can be found below:

* The bar in red indicates where Energenesis Biomedical Co's Piotroski F-Score falls into.


TPE:6657
64GF Score
Energenesis Biomedical Co Ltd TPE:6657
Piotroski F-Score is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

How is the Piotroski F-Score calculated?

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

This Year (Dec25) TTM:Last Year (Dec24) TTM:
Net Income was -96.973 + -47.629 + -49.008 + -64.792 = NT$-258.40 Mil.
Cash Flow from Operations was -115.887 + -52.086 + -35.383 + -19.054 = NT$-222.41 Mil.
Revenue was 1.213 + 2.064 + 1.582 + 2.815 = NT$7.67 Mil.
Gross Profit was 0.98 + 1.596 + 1.238 + 2.018 = NT$5.83 Mil.
Average Total Assets from the begining of this year (Dec24)
to the end of this year (Dec25) was
(780.638 + 1124.133 + 1065.042 + 1031.8 + 948.982) / 5 = NT$990.119 Mil.
Total Assets at the begining of this year (Dec24) was NT$780.64 Mil.
Long-Term Debt & Capital Lease Obligation was NT$9.29 Mil.
Total Current Assets was NT$864.43 Mil.
Total Current Liabilities was NT$43.42 Mil.
Net Income was -42.792 + -48.718 + -89.683 + -49.887 = NT$-231.08 Mil.

Revenue was 1.408 + 1.63 + 2.115 + 2.596 = NT$7.75 Mil.
Gross Profit was 1.105 + 1.229 + 1.407 + 1.949 = NT$5.69 Mil.
Average Total Assets from the begining of last year (Dec23)
to the end of last year (Dec24) was
(828.57 + 803.067 + 753.686 + 673.224 + 780.638) / 5 = NT$767.837 Mil.
Total Assets at the begining of last year (Dec23) was NT$828.57 Mil.
Long-Term Debt & Capital Lease Obligation was NT$5.47 Mil.
Total Current Assets was NT$687.75 Mil.
Total Current Liabilities was NT$35.83 Mil.

*Note: If the latest quarterly/semi-annual/annual total assets data is 0, then we will use previous quarterly/semi-annual/annual data for all the items in the balance sheet.

Profitability

Question 1. Return on Assets (ROA)

Net income before extraordinary items for the year divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Energenesis Biomedical Co's current Net Income (TTM) was -258.40. ==> Negative ==> Score 0.

Question 2. Cash Flow Return on Assets (CFROA)

Net cash flow from operating activities (operating cash flow) divided by Total Assets at the beginning of the year.

Score 1 if positive, 0 if negative.

Energenesis Biomedical Co's current Cash Flow from Operations (TTM) was -222.41. ==> Negative ==> Score 0.

Question 3. Change in Return on Assets

Compare this year's return on assets (1) to last year's return on assets.

Score 1 if it's higher, 0 if it's lower.

ROA (This Year)=Net Income/Total Assets (Dec24)
=-258.402/780.638
=-0.33101386

ROA (Last Year)=Net Income/Total Assets (Dec23)
=-231.08/828.57
=-0.27889014

Energenesis Biomedical Co's return on assets of this year was -0.33101386. Energenesis Biomedical Co's return on assets of last year was -0.27889014. ==> Last year is higher ==> Score 0.

Question 4. Quality of Earnings (Accrual)

Compare Cash flow return on assets (2) to return on assets (1)

Score 1 if CFROA > ROA, 0 if CFROA <= ROA.

Energenesis Biomedical Co's current Net Income (TTM) was -258.40. Energenesis Biomedical Co's current Cash Flow from Operations (TTM) was -222.41. ==> -222.41 > -258.40 ==> CFROA > ROA ==> Score 1.

Funding

Question 5. Change in Gearing or Leverage

Compare this year's gearing (long-term debt divided by average total assets) to last year's gearing.

Score 0 if this year's gearing is higher, 1 otherwise.

Gearing (This Year: Dec25)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Dec24 to Dec25
=9.287/990.119
=0.00937968

Gearing (Last Year: Dec24)=Long-Term Debt & Capital Lease Obligation/Average Total Assets from Dec23 to Dec24
=5.473/767.837
=0.00712781

Energenesis Biomedical Co's gearing of this year was 0.00937968. Energenesis Biomedical Co's gearing of last year was 0.00712781. ==> Last year is lower than this year ==> Score 0.

Question 6. Change in Working Capital (Liquidity)

Compare this year's current ratio (current assets divided by current liabilities) to last year's current ratio.

Score 1 if this year's current ratio is higher, 0 if it's lower

Current Ratio (This Year: Dec25)=Total Current Assets/Total Current Liabilities
=864.431/43.422
=19.90767353

Current Ratio (Last Year: Dec24)=Total Current Assets/Total Current Liabilities
=687.746/35.832
=19.19362581

Energenesis Biomedical Co's current ratio of this year was 19.90767353. Energenesis Biomedical Co's current ratio of last year was 19.19362581. ==> This year's current ratio is higher. ==> Score 1.

Question 7. Change in Shares in Issue

Compare the number of shares in issue this year, to the number in issue last year.

Score 0 if there is larger number of shares in issue this year, 1 otherwise.

Energenesis Biomedical Co's number of shares in issue this year was 88.664. Energenesis Biomedical Co's number of shares in issue last year was 77.186. ==> There is larger number of shares in issue this year. ==> Score 0.

Efficiency

Question 8. Change in Gross Margin

Compare this year's gross margin (Gross Profit divided by sales) to last year's.

Score 1 if this year's gross margin is higher, 0 if it's lower.

Gross Margin (This Year: TTM)=Gross Profit/Revenue
=5.832/7.674
=0.75996873

Gross Margin (Last Year: TTM)=Gross Profit/Revenue
=5.69/7.749
=0.7342883

Energenesis Biomedical Co's gross margin of this year was 0.75996873. Energenesis Biomedical Co's gross margin of last year was 0.7342883. ==> This year's gross margin is higher. ==> Score 1.

Question 9. Change in asset turnover

Compare this year's asset turnover (total sales for the year divided by total assets at the beginning of the year) to last year's asset turnover ratio.

Score 1 if this year's asset turnover ratio is higher, 0 if it's lower

Asset Turnover (This Year)=Revenue/Total Assets at the Beginning of This Year (Dec24)
=7.674/780.638
=0.00983042

Asset Turnover (Last Year)=Revenue/Total Assets at the Beginning of Last Year (Dec23)
=7.749/828.57
=0.00935226

Energenesis Biomedical Co's asset turnover of this year was 0.00983042. Energenesis Biomedical Co's asset turnover of last year was 0.00935226. ==> This year's asset turnover is higher. ==> Score 1.

Evaluation

Piotroski F-Score= Que. 1+ Que. 2+ Que. 3+Que. 4+Que. 5+Que. 6+Que. 7+Que. 8+Que. 9
=0+0+0+1+0+1+0+1+1
=4

Good or high score = 7, 8, 9
Bad or low score = 0, 1, 2, 3

Energenesis Biomedical Co has an F-score of 4 indicating the company's financial situation is typical for a stable company.

Frequently Asked Questions Learn more about Piotroski F-Score →
What does a Piotroski F-Score of 4 mean?
Energenesis Biomedical Co (TPE:6657) has a Piotroski F-Score of 4 as of Jun. 28, 2026. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Energenesis Biomedical Co and its competitors. This is near median its historical median of 4.00. Over the past decade, Energenesis Biomedical Co's Piotroski F-Score has ranged from 1.00 to 5.00. According to the industry distribution chart, Energenesis Biomedical Co ranks #346 out of 1340 companies in the Biotechnology industry, placing it in the top 25.8%.
Is Energenesis Biomedical Co's Piotroski F-Score too high?
Energenesis Biomedical Co's current Piotroski F-Score of 4 is near median its 10-year median of 4.00. Over the past 10 years, this metric has ranged from a low of 1.00 to a high of 5.00. The Biotechnology industry median Piotroski F-Score is 3.00. Energenesis Biomedical Co's value of 4 is 33.3% above this industry median. Based on the distribution chart, Energenesis Biomedical Co ranks #346 out of 1340 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Energenesis Biomedical Co has a GF Score™ of 64/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Energenesis Biomedical Co's Piotroski F-Score compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Energenesis Biomedical Co ranks #346 out of 1340 companies for Piotroski F-Score. This puts Energenesis Biomedical Co in the upper half of its industry. The industry median Piotroski F-Score is 3.00. Energenesis Biomedical Co's value of 4 is 33.3% above this benchmark. Historically, Energenesis Biomedical Co's own Piotroski F-Score has ranged from 1.00 to 5.00 over the past decade. While the company's 10-year median is 4.00 vs. the industry median of 3.00, Energenesis Biomedical Co has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Piotroski F-Score for a Biotechnology company?
The median Piotroski F-Score among Biotechnology companies is 3.00, based on 1,340 companies in the industry. Companies in the top quartile (top 25%) have a Piotroski F-Score significantly above this median, while those in the bottom quartile fall well below. However, Piotroski F-Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Energenesis Biomedical Co's current Piotroski F-Score of 4 is 33.3% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Piotroski F-Score mean?
A high Piotroski F-Score can signal that a stock is expensive relative to its fundamentals. The Piotroski F-score grades a company's business operating strength from 0-9. View historical data on Energenesis Biomedical Co and its competitors. For the Biotechnology industry, the median Piotroski F-Score is 3.00 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Energenesis Biomedical Co's current Piotroski F-Score is 4, which is near median its own 10-year median of 4.00. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Energenesis Biomedical Co stock overvalued right now?
Based on GuruFocus' analysis, Energenesis Biomedical Co (TPE:6657) is currently considered Possible Value Trap. The stock's GF Value™ is NT$51.28, compared to a current price of NT$34.90 — trading 31.9% below its estimated fair value. The current Piotroski F-Score is 4, which is near median its 10-year median of 4.00 and 33.3% above the Biotechnology industry median of 3.00. Energenesis Biomedical Co's overall GF Score™ is 64/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Piotroski F-Score calculated?
Piotroski F-Score is calculated from a company's financial statements. For Energenesis Biomedical Co (TPE:6657), the current Piotroski F-Score is 4 as of Jun. 28, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Energenesis Biomedical Co (TPE:6657) Overvalued in 2026?

Based on GuruFocus' analysis, Energenesis Biomedical Co stock appears to be undervalued. The current stock price of NT$34.90 is trading 31.9% below its estimated GF Value™ of NT$51.28. GuruFocus considers Energenesis Biomedical Co to be Possible Value Trap.

Key valuation signals for TPE:6657:

  • Piotroski F-Score: 4 (near median its 10-year median of 4.00)
  • GF Value™: NT$51.28 vs. price of NT$34.90 (31.9% below fair value)
  • GF Score™: 64/100 with 3 warning signs
  • Industry Position: 33.3% above the Biotechnology median (#346 of 1340)

No single metric tells the full story. See the TPE:6657 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Energenesis Biomedical Co Business Description

Address No. 21, Lane 583, Ruiguang Road, 6th Floor -3, Neihu District, Taipei, TWN, 11492
Energenesis Biomedical Co Ltd is a biomedicine company. The company is engaged in businesses related to biological experimentation and analysis, as well as new drugs development. The company uses its ENERGI drug development platform to activate AMP-activated protein kinase (AMPK), a key enzyme in cell energy regulation, as a means of developing disease treatments. The product pipeline of the company consists of ENERGI-F703, a diabetic foot ulcers treatment gel; ENERGI-F701, a product developed for male hair loss; ENERGI-F704, an inflammatory bowel disease treatment; and ENERGI-F711, a burn cream,F708, Asthama treatment, and others.
64GF Score

Get the complete analysis for TPE:6657

Piotroski F-Score is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

NT$34.90
Price
NT$51.28
GF Value