GenFleet Therapeutics (Shanghai) (HAM:Y3L) Gross Margin %: 28.50% (As of Dec. 2025) — 65% Below Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

HAM:Y3L GenFleet Therapeutics (Shanghai) Inc HAM:Y3L
19 GF Score
Price €2.92
! 3 Warning Signs
View Full Analysis

What is GenFleet Therapeutics (Shanghai) Gross Margin %?

GenFleet Therapeutics (Shanghai) HAM:Y3L -2.80% 19 Gross Margin % is 28.50% as of Dec. 2025, which is 65% below its 10-year median of 80.81. GuruFocus rates HAM:Y3L with a GF Score™ of 19/100. The stock has 3 warning signs investors should review. Among 734 Biotechnology companies, GenFleet Therapeutics (Shanghai) ranks better than 53.81% on this metric.

Gross Margin % is calculated as gross profit divided by its revenue. GenFleet Therapeutics (Shanghai)'s Gross Profit for the six months ended in Dec. 2025 was €1.44 Mil. GenFleet Therapeutics (Shanghai)'s Revenue for the six months ended in Dec. 2025 was €5.04 Mil. Therefore, GenFleet Therapeutics (Shanghai)'s Gross Margin % for the quarter that ended in Dec. 2025 was 28.50%.


The historical rank and industry rank for GenFleet Therapeutics (Shanghai)'s Gross Margin % or its related term are showing as below:

HAM:Y3L' s Gross Margin % Range Over the Past 10 Years
Min: 64.1   Med: 80.81   Max: 99.07
Current: 64.1


During the past 3 years, the highest Gross Margin % of GenFleet Therapeutics (Shanghai) was 99.07%. The lowest was 64.10%. And the median was 80.81%.

HAM:Y3L's Gross Margin % is ranked better than
53.81% of 734 companies
in the Biotechnology industry
Industry Median: 60.905 vs HAM:Y3L: 64.10

GenFleet Therapeutics (Shanghai) had a gross margin of 28.50% for the quarter that ended in Dec. 2025 => Competition eroding margins

The 5-Year average Growth Rate of Gross Margin for GenFleet Therapeutics (Shanghai) was 0.00% per year.


GenFleet Therapeutics (Shanghai)  (HAM:Y3L) Gross Margin % Explanation

Warren Buffett believes that firms with excellent long term economics tend to have consistently higher margins.

Durable competitive advantage creates a high Gross Margin % because of the freedom to price in excess of cost. Companies can be categorized by their Gross Margin %

1. Greater than 40% = Durable competitive advantage
2. Less than 40% = Competition eroding margins
3. Less than 20% = no sustainable competitive advantage
Consistency of Gross Margin is key

GenFleet Therapeutics (Shanghai) had a gross margin of 28.50% for the quarter that ended in Dec. 2025 => Competition eroding margins


Be Aware

If a company loses its competitive advantages, usually its gross margin declines well before its sales declines. Watching Gross Margin % and Operating Margin % closely helps avoid value trap situations.


GenFleet Therapeutics (Shanghai) Gross Margin % Related Terms


GenFleet Therapeutics (Shanghai) Gross Margin % Historical Data

* Premium members only.

The historical data trend for GenFleet Therapeutics (Shanghai)'s Gross Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

GenFleet Therapeutics (Shanghai) Gross Margin % Chart

GenFleet Therapeutics (Shanghai) Annual Data
Trend Dec23 Dec24 Dec25
Gross Margin %
99.08 80.81 64.22

GenFleet Therapeutics (Shanghai) Semi-Annual Data
Dec23 Jun24 Dec24 Jun25 Dec25
Gross Margin % 0.00 0.00 80.81 80.93 28.50

HAM:Y3L vs VRTX, REGN, RVMD: Gross Margin % Comparison

For the Biotechnology subindustry, GenFleet Therapeutics (Shanghai)'s Gross Margin %, along with its competitors' market caps and Gross Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


GenFleet Therapeutics (Shanghai) Gross Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, GenFleet Therapeutics (Shanghai)'s Gross Margin % distribution charts can be found below:

* The bar in red indicates where GenFleet Therapeutics (Shanghai)'s Gross Margin % falls into.


HAM:Y3L
19GF Score
GenFleet Therapeutics (Shanghai) Inc HAM:Y3L
Gross Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

GenFleet Therapeutics (Shanghai) Gross Margin % Calculation

Gross Margin is the percentage of Gross Profit out of sales or Revenue.

GenFleet Therapeutics (Shanghai)'s Gross Margin for the fiscal year that ended in Dec. 2025 is calculated as

Gross Margin % (A: Dec. 2025 )=Gross Profit (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=10.1 / 15.795
=(Revenue - Cost of Goods Sold) / Revenue
=(15.795 - 5.651) / 15.795
=64.22 %

GenFleet Therapeutics (Shanghai)'s Gross Margin for the quarter that ended in Dec. 2025 is calculated as


Gross Margin % (Q: Dec. 2025 )=Gross Profit (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=1.4 / 5.035
=(Revenue - Cost of Goods Sold) / Revenue
=(5.035 - 3.6) / 5.035
=28.50 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

A positive Gross Profit is only the first step for a company to make a net profit. The gross profit needs to be big enough to also cover related labor, equipment, rental, marketing/advertising, research and development and a lot of other costs in selling the products.

Frequently Asked Questions Learn more about Gross Margin % →
What does a Gross Margin % of 28.50% mean?
GenFleet Therapeutics (Shanghai) (HAM:Y3L) has a Gross Margin % of 28.50% as of Dec. 2025. Gross margin is the ratio of total gross profit to net sales. View historical data on GenFleet Therapeutics (Shanghai) and its competitors. This is 65% below median its historical median of 80.81. Over the past decade, GenFleet Therapeutics (Shanghai)'s Gross Margin % has ranged from 64.10 to 99.07. According to the industry distribution chart, GenFleet Therapeutics (Shanghai) ranks #339 out of 734 companies in the Biotechnology industry, placing it in the top 46.2%.
Is GenFleet Therapeutics (Shanghai)'s Gross Margin % too high?
GenFleet Therapeutics (Shanghai)'s current Gross Margin % of 28.50% is 65% below median its 10-year median of 80.81. Over the past 10 years, this metric has ranged from a low of 64.10 to a high of 99.07. The Biotechnology industry median Gross Margin % is 60.91. GenFleet Therapeutics (Shanghai)'s value of 28.50% is 53.2% below this industry median. Based on the distribution chart, GenFleet Therapeutics (Shanghai) ranks #339 out of 734 companies in the Biotechnology industry, which is above the industry midpoint. Overall, GenFleet Therapeutics (Shanghai) has a GF Score™ of 19/100, reflecting its overall financial health beyond just this single metric.
How does GenFleet Therapeutics (Shanghai)'s Gross Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, GenFleet Therapeutics (Shanghai) ranks #339 out of 734 companies for Gross Margin %. This puts GenFleet Therapeutics (Shanghai) in the upper half of its industry. The industry median Gross Margin % is 60.91. GenFleet Therapeutics (Shanghai)'s value of 28.50% is 53.2% below this benchmark. Historically, GenFleet Therapeutics (Shanghai)'s own Gross Margin % has ranged from 64.10 to 99.07 over the past decade. While the company's 10-year median is 80.81 vs. the industry median of 60.91, GenFleet Therapeutics (Shanghai) has consistently been below the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Gross Margin % for a Biotechnology company?
The median Gross Margin % among Biotechnology companies is 60.91, based on 734 companies in the industry. Companies in the top quartile (top 25%) have a Gross Margin % significantly above this median, while those in the bottom quartile fall well below. However, Gross Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. GenFleet Therapeutics (Shanghai)'s current Gross Margin % of 28.50% is 53.2% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Gross Margin % mean?
A high Gross Margin % can signal that a stock is expensive relative to its fundamentals. Gross margin is the ratio of total gross profit to net sales. View historical data on GenFleet Therapeutics (Shanghai) and its competitors. For the Biotechnology industry, the median Gross Margin % is 60.91 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. GenFleet Therapeutics (Shanghai)'s current Gross Margin % is 28.50%, which is 65% below median its own 10-year median of 80.81. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is GenFleet Therapeutics (Shanghai) stock overvalued right now?
GenFleet Therapeutics (Shanghai) (HAM:Y3L) has a current Gross Margin % of 28.50%. The current Gross Margin % is 28.50%, which is 65% below median its 10-year median of 80.81 and 53.2% below the Biotechnology industry median of 60.91. GenFleet Therapeutics (Shanghai)'s overall GF Score™ is 19/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Gross Margin % calculated?
Gross Margin % is calculated from a company's financial statements. For GenFleet Therapeutics (Shanghai) (HAM:Y3L), the current Gross Margin % is 28.50% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

GenFleet Therapeutics (Shanghai) Business Description

Other Exchanges 02595:Hong Kong
Address 1206 Zhangjiang Road, Floors 2nd, 3rd, 4th, and 5th, Building 8, Shanghai Pilot Free Trade Zone, Shanghai, CHN, 201203
GenFleet Therapeutics (Shanghai) Inc Company is a clinical-stage biotechnology company. The Company and its subsidiaries are principally engaged in the research, development and commercialisation of pharmaceutical products. The Group is engaged in biopharmaceutical research and development, which is regarded as a single reportable segment.
19GF Score

Get the complete analysis for HAM:Y3L

Gross Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€2.92
Price