Proteome Sciences (CHIX:PRML) Gross Profit: £-0.08 Mil (TTM As of Dec. 2025)

What is Proteome Sciences Gross Profit?

Proteome Sciences CHIX:PRML +7.63% Gross Profit is £-0.08 Mil as of Dec. 2025. The stock has 6 warning signs investors should review.

Proteome Sciences's gross profit for the six months ended in Dec. 2025 was £-0.41 Mil. Proteome Sciences's gross profit for the trailing twelve months (TTM) ended in Dec. 2025 was £-0.08 Mil.

Gross Margin % is calculated as gross profit divided by its revenue. Proteome Sciences's gross profit for the six months ended in Dec. 2025 was £-0.41 Mil. Proteome Sciences's Revenue for the six months ended in Dec. 2025 was £1.90 Mil. Therefore, Proteome Sciences's Gross Margin % for the quarter that ended in Dec. 2025 was -21.33%.

Proteome Sciences had a gross margin of -21.33% for the quarter that ended in Dec. 2025 => No sustainable competitive advantage

During the past 13 years, the highest Gross Margin % of Proteome Sciences was 65.09%. The lowest was -2.16%. And the median was 57.06%.

Proteome Sciences (CHIX:PRMl) Gross Profit Explanation

Warren Buffett believes that firms with excellent long term economics tend to have consistently higher margins.

Durable competitive advantage creates a high Gross Margin % because of the freedom to price in excess of cost. Companies can be categorized by their Gross Margin %

1. Greater than 40% = Durable competitive advantage
2. Less than 40% = Competition eroding margins
3. Less than 20% = no sustainable competitive advantage
Consistency of Gross Margin is key

Proteome Sciences had a gross margin of -21.33% for the quarter that ended in Dec. 2025 => No sustainable competitive advantage

Proteome Sciences Gross Profit Related Terms

Proteome Sciences Gross Profit Historical Data

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The historical data trend for Proteome Sciences's Gross Profit can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Proteome Sciences Gross Profit Chart

Proteome Sciences Annual Data

Trend

Dec16

Dec17

Dec18

Dec19

Dec20

Dec21

Dec22

Dec23

Dec24

Dec25

Gross Profit

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2.96

4.77

1.65

0.67

-0.08

Proteome Sciences Semi-Annual Data
	Jun16	Dec16	Jun17	Dec17	Jun18	Dec18	Jun19	Dec19	Jun20	Dec20	Jun21	Dec21	Jun22	Dec22	Jun23	Dec23	Jun24	Dec24	Jun25	Dec25
Gross Profit	Get a 7-Day Free Trial															-0.12	0.21	0.47	0.32	-0.41

CHIX:PRML vs TMO, DHR, IDXX: Gross Profit Comparison

For the Diagnostics & Research subindustry, Proteome Sciences's Gross Profit, along with its competitors' market caps and Gross Profit data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Proteome Sciences Gross Profit vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Proteome Sciences's Gross Profit distribution charts can be found below:

* The bar in red indicates where Proteome Sciences's Gross Profit falls into.

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Proteome Sciences Gross Profit Calculation

Gross Profit is the different between the sale prices and the cost of buying or producing the goods.

Proteome Sciences's Gross Profit for the fiscal year that ended in Dec. 2025 is calculated as

Gross Profit (A: Dec. 2025 )	=	Revenue	-	Cost of Goods Sold
	=	3.756	-	3.837
	=	-0.08

Proteome Sciences's Gross Profit for the quarter that ended in Dec. 2025 is calculated as

Gross Profit (Q: Dec. 2025 )	=	Revenue	-	Cost of Goods Sold
	=	1.899	-	2.304
	=	-0.41

Gross Profit for the trailing twelve months (TTM) ended in Dec. 2025 adds up the semi-annually data reported by the company within the most recent 12 months, which was £-0.08 Mil.

Gross Profit is the numerator in the calculation of Gross Margin.

Proteome Sciences's Gross Margin % for the quarter that ended in Dec. 2025 is calculated as

Gross Margin % (Q: Dec. 2025 )	=	Gross Profit (Q: Dec. 2025 )	/	Revenue (Q: Dec. 2025 )
	=	(Revenue - Cost of Goods Sold)	/	Revenue
	=	-0.41	/	1.899
	=	-21.33 %

A positive Gross Profit is only the first step for a company to make a net profit. The gross profit needs to be big enough to also cover related labor, equipment, rental, marketing/advertising, research and development and a lot of other costs in selling the products.

Frequently Asked Questions Learn more about Gross Profit →

What does a Gross Profit of £-0.08 Mil mean?

Proteome Sciences (CHIX:PRML) has a Gross Profit of £-0.08 Mil as of Dec. 2025. Gross Profit equals net sales less total cost of goods sold. View historical data on Proteome Sciences and its competitors.

Is Proteome Sciences' Gross Profit too high?

Proteome Sciences' current Gross Profit is £-0.08 Mil.

How does Proteome Sciences' Gross Profit compare to TMO and DHR?

Proteome Sciences' Gross Profit of £-0.08 Mil can be compared against companies in the Medical Diagnostics & Research industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.

What is a good Gross Profit for a Medical Diagnostics & Research company?

A good Gross Profit depends on the Medical Diagnostics & Research industry context. However, Gross Profit should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.

What does a high Gross Profit mean?

A high Gross Profit can signal that a stock is expensive relative to its fundamentals. Gross Profit equals net sales less total cost of goods sold. View historical data on Proteome Sciences and its competitors. Proteome Sciences's current Gross Profit is £-0.08 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.

Is Proteome Sciences stock overvalued right now?

Based on GuruFocus' analysis, Proteome Sciences (CHIX:PRML) is currently considered Modestly Undervalued. The stock's GF Value™ is £0.02, compared to a current price of £0.01 — trading 29.5% below its estimated fair value. The current Gross Profit is £-0.08 Mil. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.

How is Gross Profit calculated?

Gross Profit is calculated from a company's financial statements. For Proteome Sciences (CHIX:PRML), the current Gross Profit is £-0.08 Mil as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Proteome Sciences Business Description

Industry Healthcare Medical Diagnostics & Research

Comparable Companies LSE:OBD LSE:GENI LSE:VRCI LSE:GDR LSE:ABDX LSE:CLBX TMO DHR SHSE:603259 XSWX:LONN IDXX A NTRA WAT IQV ILMN MTD DGX LH GH

Other Exchanges PRM:UK PI2:Germany

Address Downside Bridge Road, Coveham House, Cobham, Surrey, GBR, KT11 3EP

Website https://www.proteomics.com

Proteome Sciences PLC is engaged in protein biomarker research and development. The company is a provider of contract research services for the identification, validation and application of protein biomarkers. The company's only reportable segment is the sale of goods and biomarker services. The company generates maximum revenue from the TMT product and end customer sales-based royalties. Geographically, it has a presence in the United States, the United Kingdom, the European Union, and Others.