Duality Biotherapeutics (FRA:4ZB) Gross Profit: €-30.5 Mil (TTM As of Jun. 2026)

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FRA:4ZB Duality Biotherapeutics Inc FRA:4ZB
19 GF Score
Price €21.60
! 2 Warning Signs
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What is Duality Biotherapeutics Gross Profit?

Duality Biotherapeutics FRA:4ZB +6.93% 19 Gross Profit is €-30.5 Mil as of Jun. 2026. GuruFocus rates FRA:4ZB with a GF Score™ of 19/100. The stock has 2 warning signs investors should review.

Duality Biotherapeutics's gross profit for the six months ended in Jun. 2026 was €-30.0 Mil. Duality Biotherapeutics's gross profit for the trailing twelve months (TTM) ended in Jun. 2026 was €-30.5 Mil.

Gross Margin % is calculated as gross profit divided by its revenue. Duality Biotherapeutics's gross profit for the six months ended in Jun. 2026 was €-30.0 Mil. Duality Biotherapeutics's Revenue for the six months ended in Jun. 2026 was €27.4 Mil. Therefore, Duality Biotherapeutics's Gross Margin % for the quarter that ended in Jun. 2026 was -109.68%.

Duality Biotherapeutics had a gross margin of -109.68% for the quarter that ended in Jun. 2026 => No sustainable competitive advantage

During the past 4 years, the highest Gross Margin % of Duality Biotherapeutics was 76.06%. The lowest was -28.70%. And the median was 40.42%.


Duality Biotherapeutics  (FRA:4ZB) Gross Profit Explanation

Warren Buffett believes that firms with excellent long term economics tend to have consistently higher margins.

Durable competitive advantage creates a high Gross Margin % because of the freedom to price in excess of cost. Companies can be categorized by their Gross Margin %

1. Greater than 40% = Durable competitive advantage
2. Less than 40% = Competition eroding margins
3. Less than 20% = no sustainable competitive advantage
Consistency of Gross Margin is key

Duality Biotherapeutics had a gross margin of -109.68% for the quarter that ended in Jun. 2026 => No sustainable competitive advantage


Duality Biotherapeutics Gross Profit Related Terms


Duality Biotherapeutics Gross Profit Historical Data

* Premium members only.

The historical data trend for Duality Biotherapeutics's Gross Profit can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Duality Biotherapeutics Gross Profit Chart

Duality Biotherapeutics Annual Data
Trend Dec22 Dec23 Dec24 Dec25
Gross Profit
-0.03 176.76 99.78 71.71

Duality Biotherapeutics Semi-Annual Data
Jun25 Dec25 Jun26
Gross Profit 74.01 -0.49 -30.05

FRA:4ZB vs VRTX, REGN, MRNA: Gross Profit Comparison

For the Biotechnology subindustry, Duality Biotherapeutics's Gross Profit, along with its competitors' market caps and Gross Profit data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Duality Biotherapeutics Gross Profit vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Duality Biotherapeutics's Gross Profit distribution charts can be found below:

* The bar in red indicates where Duality Biotherapeutics's Gross Profit falls into.


FRA:4ZB
19GF Score
Duality Biotherapeutics Inc FRA:4ZB
Gross Profit is just one metric. See GF Score™, valuation, warning signs, and more.
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Duality Biotherapeutics Gross Profit Calculation

Gross Profit is the different between the sale prices and the cost of buying or producing the goods.

Duality Biotherapeutics's Gross Profit for the fiscal year that ended in Dec. 2025 is calculated as

Gross Profit (A: Dec. 2025 )=Revenue - Cost of Goods Sold
=228.25070890661 - 156.54199537117
=71.7

Duality Biotherapeutics's Gross Profit for the quarter that ended in Jun. 2026 is calculated as

Gross Profit (Q: Jun. 2026 )=Revenue - Cost of Goods Sold
=27.39471584378 - 57.441471999013
=-30.0

Gross Profit for the trailing twelve months (TTM) ended in Jun. 2026 adds up the semi-annually data reported by the company within the most recent 12 months, which was €-30.5 Mil.

Gross Profit is the numerator in the calculation of Gross Margin.

Duality Biotherapeutics's Gross Margin % for the quarter that ended in Jun. 2026 is calculated as

Gross Margin % (Q: Jun. 2026 )=Gross Profit (Q: Jun. 2026 ) / Revenue (Q: Jun. 2026 )
=(Revenue - Cost of Goods Sold) / Revenue
=-30.0 / 27.39471584378
=-109.68 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

A positive Gross Profit is only the first step for a company to make a net profit. The gross profit needs to be big enough to also cover related labor, equipment, rental, marketing/advertising, research and development and a lot of other costs in selling the products.

Frequently Asked Questions Learn more about Gross Profit →
What does a Gross Profit of €-30.5 Mil mean?
Duality Biotherapeutics (FRA:4ZB) has a Gross Profit of €-30.5 Mil as of Jun. 2026. Gross Profit equals net sales less total cost of goods sold. View historical data on Duality Biotherapeutics and its competitors.
Is Duality Biotherapeutics' Gross Profit too high?
Duality Biotherapeutics' current Gross Profit is €-30.5 Mil. Overall, Duality Biotherapeutics has a GF Score™ of 19/100, reflecting its overall financial health beyond just this single metric.
How does Duality Biotherapeutics' Gross Profit compare to VRTX and REGN?
Duality Biotherapeutics' Gross Profit of €-30.5 Mil can be compared against companies in the Biotechnology industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Gross Profit for a Biotechnology company?
A good Gross Profit depends on the Biotechnology industry context. However, Gross Profit should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Gross Profit mean?
A high Gross Profit can signal that a stock is expensive relative to its fundamentals. Gross Profit equals net sales less total cost of goods sold. View historical data on Duality Biotherapeutics and its competitors. Duality Biotherapeutics's current Gross Profit is €-30.5 Mil. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Duality Biotherapeutics stock overvalued right now?
Duality Biotherapeutics (FRA:4ZB) has a current Gross Profit of €-30.5 Mil. The current Gross Profit is €-30.5 Mil. Duality Biotherapeutics' overall GF Score™ is 19/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Gross Profit calculated?
Gross Profit is calculated from a company's financial statements. For Duality Biotherapeutics (FRA:4ZB), the current Gross Profit is €-30.5 Mil as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Duality Biotherapeutics Business Description

Other Exchanges 09606:Hong Kong
Address No. 868 Yinghua Road, 11th Floor, Building A, Jian Gong Datang International Plaza, Pudong New Area, Shanghai, CHN
Duality Biotherapeutics Inc is engaged in the discovery and development of antibody-drug conjugate (ADC) therapeutics, focusing on treatments for cancer and other diseases. The company has a diversified pipeline of ADC candidates, including two core products: DB-1303/BNT323, a HER2-targeting ADC for cancers such as breast and endometrial cancer, and DB-1311/BNT324, a B7-H3-targeting ADC for multiple solid tumors. In addition, it has several other clinical-stage ADC candidates with therapeutic potential, as well as multiple preclinical ADCs, including candidates expected to enter clinical trials. Its key products, including DB-1303/BNT323, DB-1311/BNT324, and DB-1305/BNT325, have received Fast Track Designation, with DB-1303 being a late-stage candidate undergoing registrational studies.
19GF Score

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Gross Profit is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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