CSTL (Castle Biosciences) YoY EPS Growth: -146.67% (As of Jun. 2026)

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CSTL Castle Biosciences Inc CSTL
83 GF Score
Price $32.97
GF Value $29.79
Valuation Modestly Overvalued
! 4 Warning Signs
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What is Castle Biosciences YoY EPS Growth?

Castle Biosciences CSTL +0.75% 83 YoY EPS Growth is -146.67% as of Jun. 2026. GuruFocus rates CSTL with a GF Score™ of 83/100 and a GF Value™ of $29.79 (Modestly Overvalued). The stock has 4 warning signs investors should review.

YoY EPS Growth is the percentage change of Earnings per Share (Diluted) over the past twelve months. Castle Biosciences's YoY EPS Growth for the quarter that ended in Jun. 2026 was -146.67%.

Castle Biosciences's Earnings per Share (Diluted) for the three months ended in Jun. 2026 was $-0.07.

Castle Biosciences YoY EPS Growth Historical Data

* Premium members only.

The historical data trend for Castle Biosciences's YoY EPS Growth can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Castle Biosciences YoY EPS Growth Chart

Castle Biosciences Annual Data
Trend Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
YoY EPS Growth
Get a 7-Day Free Trial Premium Member Only -129.63 -108.06 17.05 128.97 -233.87

Castle Biosciences Quarterly Data
Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26 Jun26
YoY EPS Growth Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -51.61 -125.00 -125.00 45.56 -146.67
CSTL
83GF Score
Castle Biosciences Inc CSTL
YoY EPS Growth is just one metric. See GF Score™, valuation, warning signs, and more.
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Castle Biosciences YoY EPS Growth Calculation

YoY EPS Growth is the percentage change of Earnings per Share (Diluted) over the past twelve months.

Castle Biosciences's YoY EPS Growth for the fiscal year that ended in Dec. 2025 is calculated as:

YoY EPS Growth (A: Dec. 2025 )
=(Earnings per Share (Diluted) (A: Dec. 2025 )-Earnings per Share (Diluted) (A: Dec. 2024 ))/ | Earnings per Share (Diluted) (A: Dec. 2024 ) |
=(-0.83-0.62)/ | 0.62 |
=-233.87 %

Castle Biosciences's YoY EPS Growth for the quarter that ended in Jun. 2026 is calculated as:

YoY EPS Growth (Q: Jun. 2026 )
=(Earnings per Share (Diluted) (Q: Jun. 2026 )-Earnings per Share (Diluted) (Q: Jun. 2025 )) / | Earnings per Share (Diluted) (Q: Jun. 2025 )) |
=(-0.07-0.15)/ | 0.15 |
=-146.67 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about YoY EPS Growth →
What does a YoY EPS Growth of -146.67% mean?
Castle Biosciences (CSTL) has a YoY EPS Growth of -146.67% as of Jun. 2026. YoY EPS Growth is the percentage change of EPS over the past 12-month. View historical data for Castle Biosciences and its competitors.
Is Castle Biosciences' YoY EPS Growth too high?
Castle Biosciences' current YoY EPS Growth is -146.67%. Overall, Castle Biosciences has a GF Score™ of 83/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Castle Biosciences' YoY EPS Growth compare to OPK and FLGT?
Castle Biosciences' YoY EPS Growth of -146.67% can be compared against companies in the Medical Diagnostics & Research industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good YoY EPS Growth for a Medical Diagnostics & Research company?
A good YoY EPS Growth depends on the Medical Diagnostics & Research industry context. However, YoY EPS Growth should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high YoY EPS Growth mean?
A high YoY EPS Growth can signal that a stock is expensive relative to its fundamentals. YoY EPS Growth is the percentage change of EPS over the past 12-month. View historical data for Castle Biosciences and its competitors. Castle Biosciences's current YoY EPS Growth is -146.67%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Castle Biosciences stock overvalued right now?
Based on GuruFocus' analysis, Castle Biosciences (CSTL) is currently considered Modestly Overvalued. The stock's GF Value™ is $29.79, compared to a current price of $32.97 — trading 10.7% above its estimated fair value. The current YoY EPS Growth is -146.67%. Castle Biosciences' overall GF Score™ is 83/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is YoY EPS Growth calculated?
YoY EPS Growth is calculated from a company's financial statements. For Castle Biosciences (CSTL), the current YoY EPS Growth is -146.67% as of Jun. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Castle Biosciences (CSTL) Overvalued in 2026?

Based on GuruFocus' analysis, Castle Biosciences stock appears to be overvalued. The current stock price of $32.97 is trading 10.7% above its estimated GF Value™ of $29.79. GuruFocus considers Castle Biosciences to be Modestly Overvalued.

Key valuation signals for CSTL:

  • YoY EPS Growth: -146.67%
  • GF Value™: $29.79 vs. price of $32.97 (10.7% above fair value)
  • GF Score™: 83/100 with 4 warning signs

No single metric tells the full story. See the CSTL stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

Castle Biosciences Business Description

Other Exchanges 086:Germany
Address 1500 West Parkwood Avenue, Suite 401, Friendswood, TX, USA, 77546
Castle Biosciences Inc is a molecular diagnostics company. The group provides test solutions for the diagnosis and treatment of dermatologic cancers, Barrett's esophagus (BE), and uveal melanoma. The product portfolio of the company includes DecisionDx-Melanoma, a risk stratification gene expression profile (GEP) test; DecisionDx-SCC, a risk stratification test for cutaneous squamous cell carcinoma; MyPath Melanoma, a diagnostic GEP test for use in patients with difficult-to-diagnose melanocytic lesions; and TissueCypher, a test to predict future development of progression of high-grade dysplasia and/or esophageal cancer. The company derives revenues through the delivery of test reports for its molecular diagnostic tests.
83GF Score

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YoY EPS Growth is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$32.97
Price
$29.79
GF Value