Twist Bioscience (MIL:1TWST) Moat Score: 5/10 (As of Aug. 07, 2026)

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MIL:1TWST Twist Bioscience Corp MIL:1TWST
47 GF Score
Price €97.44
GF Value €46.60
Valuation Significantly Overvalued
! 5 Warning Signs
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What is Twist Bioscience Moat Score?

Twist Bioscience MIL:1TWST +0.64% 47 Moat Score is 5 as of Aug. 07, 2026. GuruFocus rates MIL:1TWST with a GF Score™ of 47/100 and a GF Value™ of €46.60 (Significantly Overvalued). The stock has 5 warning signs investors should review. Among 214 Medical Diagnostics & Research companies, Twist Bioscience ranks better than 87.38% on this metric.

Twist Bioscience has the Moat Score of 5, which implies that the company might have Narrow Moat - Solid narrow moat.

Twist Bioscience has Narrow Moat: Twist Bioscience Corp has a solid narrow moat due to its proprietary DNA synthesis technology and strong R&D capabilities. However, it faces competition from larger biotech firms, limiting its moat to a solid narrow level.

Moat Score is a ranking system developed by GuruFocus to assess a company's ability to sustain a competitive advantage, rated on a scale from 0 to 10. It takes into account key factors such as market leadership, cost advantages, network effects, customer switching costs, and more.

The company's Moat Score is based on these criteria:

1. Market leadership and sustainable market share
2. Network effects and significant customer switching costs
3. Valuable intellectual property and patents
4. Strong brand strength and deep customer loyalty
5. Durable cost advantages (e.g., economies of scale, proprietary technology)
6. Significant regulatory barriers and exclusive licenses
7. Superior distribution network
8. Strong and sustainable pricing power
9. Consistent and impactful innovation and R&D capabilities

Based on the research, GuruFocus believes Twist Bioscience might have Narrow Moat - Solid narrow moat.

Twist Bioscience  (MIL:1TWST) Moat Score Explanation

The Moat Score ranges from 0 to 10, with 10 as the highest. GuruFocus divided Moat Score into following 8 categories:

Moat Score Moat Level
10Wide Moat - Exceptionally dominant and durable wide moat
8 - 9Wide Moat - Clear and robust wide moat
7Wide Moat - Entry-level wide moat, clearly possessing durable advantages
6Narrow Moat - Strong narrow moat, clearly distinguishable but not wide
5Narrow Moat - Solid narrow moat
4Narrow Moat - Discernible but modest moat
1 - 3No Moat - Very weak/transient advantages
0No Moat - No discernible moat

Twist Bioscience Moat Score Related Terms

MIL:1TWST vs BLLN, SHC, RDNT: Moat Score Comparison

For the Diagnostics & Research subindustry, Twist Bioscience's Moat Score, along with its competitors' market caps and Moat Score data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Twist Bioscience Moat Score vs Medical Diagnostics & Research Industry

For the Medical Diagnostics & Research industry and Healthcare sector, Twist Bioscience's Moat Score distribution charts can be found below:

* The bar in red indicates where Twist Bioscience's Moat Score falls into.


MIL:1TWST
47GF Score
Twist Bioscience Corp MIL:1TWST
Moat Score is just one metric. See GF Score™, valuation, warning signs, and more.
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Frequently Asked Questions Learn more about Moat Score →
What does a Moat Score of 5 mean?
Twist Bioscience (MIL:1TWST) has a Moat Score of 5 as of Aug. 07, 2026. Moat Score is a ranking system developed by GuruFocus to assess a company's ability to sustain a competitive advantage, rated on a scale from 0 to 10. It takes into account key factors such as market leadership, cost advantages, network effects, customer switching costs, and more. According to the industry distribution chart, Twist Bioscience ranks #27 out of 214 companies in the Medical Diagnostics & Research industry, placing it in the top 12.6%.
Is Twist Bioscience's Moat Score too high?
Twist Bioscience's current Moat Score is 5. Based on the distribution chart, Twist Bioscience ranks #27 out of 214 companies in the Medical Diagnostics & Research industry, which is in the top quartile — a strong position relative to peers. Overall, Twist Bioscience has a GF Score™ of 47/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Twist Bioscience's Moat Score compare to BLLN and SHC?
According to the Medical Diagnostics & Research industry distribution chart, Twist Bioscience ranks #27 out of 214 companies for Moat Score. This places Twist Bioscience in the top 13% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Moat Score for a Medical Diagnostics & Research company?
A good Moat Score depends on the Medical Diagnostics & Research industry context. However, Moat Score should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Moat Score mean?
A high Moat Score can signal that a stock is expensive relative to its fundamentals. Moat Score is a ranking system developed by GuruFocus to assess a company's ability to sustain a competitive advantage, rated on a scale from 0 to 10. It takes into account key factors such as market leadership, cost advantages, network effects, customer switching costs, and more. Twist Bioscience's current Moat Score is 5. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Twist Bioscience stock overvalued right now?
Based on GuruFocus' analysis, Twist Bioscience (MIL:1TWST) is currently considered Significantly Overvalued. The stock's GF Value™ is €46.60, compared to a current price of €97.44 — trading 109.1% above its estimated fair value. The current Moat Score is 5. Twist Bioscience's overall GF Score™ is 47/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Moat Score calculated?
Moat Score is calculated from a company's financial statements. For Twist Bioscience (MIL:1TWST), the current Moat Score is 5 as of Aug. 07, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Twist Bioscience (MIL:1TWST) Overvalued in 2026?

Based on GuruFocus' analysis, Twist Bioscience stock appears to be overvalued. The current stock price of €97.44 is trading 109.1% above its estimated GF Value™ of €46.60. GuruFocus considers Twist Bioscience to be Significantly Overvalued.

Key valuation signals for MIL:1TWST:

  • Moat Score: 5
  • GF Value™: €46.60 vs. price of €97.44 (109.1% above fair value)
  • GF Score™: 47/100 with 5 warning signs

No single metric tells the full story. See the MIL:1TWST stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.

Twist Bioscience Business Description

Other Exchanges TWST:USA0ME:Germany
Address 681 Gateway Boulevard, South San Francisco, CA, USA, 94080
Twist Bioscience Corp is a synthetic biology company that has developed a disruptive DNA synthesis platform to industrialize the engineering of biology. The company's proprietary semiconductor-based manufacturing process synthesizes DNA on silicon rather than traditional plastic plates, enabling the production of high-quality synthetic DNA faster, more affordably, and at scale. This platform overcomes conventional inefficiencies, supports cost-effective, high-throughput synthesis, and allows researchers to accelerate innovation. Geographically, the company operates across the Americas, EMEA, and APAC, deriving the majority of its revenue from the Americas.
47GF Score

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Moat Score is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€97.44
Price
€46.60
GF Value