GANX (Gain Therapeutics) Net Debt Paydown Yield % : 0.05% (As of Jul. 09, 2026) — 87% Below Median


GANX Gain Therapeutics Inc GANX
32 GF Score
Price $1.82
! 2 Warning Signs
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What is Gain Therapeutics Net Debt Paydown Yield %?

Gain Therapeutics GANX 32 Net Debt Paydown Yield % is 0.05% as of Jul. 09, 2026, which is 87% below its 10-year median of 0.38. GuruFocus rates GANX with a GF Score™ of 32/100. The stock has 2 warning signs investors should review. Among 1,158 Biotechnology companies, Gain Therapeutics ranks better than 52.07% on this metric.

Net Debt Paydown Yield % is a metric that evaluates the total amount of debt a company has paid in relation to its market capitalization. It is a measure of a company's willingness and ability to reduce its debt. As of today, Gain Therapeutics's Net Debt Paydown Yield % was 0.05%.


Gain Therapeutics  (NAS:GANX) Net Debt Paydown Yield % Explanation

Net Debt Paydown Yield % is the change in average of four quarters of company's total debt over a company's market cap. Assuming the total value of a company remains that same, shareholder value is increased as debt is reduced. In other words, it is a measure of the willingness and ability of a firm's management to pay down debt. Companies that have high debt paydown yields indicate that they are more aggressive with paying down debt.

In the calculation of Net Debt Paydown Yield %, we use the reductions of TTM average total debt one-year-ago and TTM average total debt at present, divided by its Market Cap.

We calculating the TTM average debt by adding up the total debt, calculated by the sum of Short-Term Debt & Capital Lease Obligation and Long-Term Debt & Capital Lease Obligation, in the trailing twelve months(TTM) divided by the counts of the total debt, accoring to the company's report frequency.


Gain Therapeutics Net Debt Paydown Yield % Related Terms


Gain Therapeutics Net Debt Paydown Yield % Historical Data

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The historical data trend for Gain Therapeutics's Net Debt Paydown Yield % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Gain Therapeutics Net Debt Paydown Yield % Chart

Gain Therapeutics Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Net Debt Paydown Yield %
Get a 7-Day Free Trial -0.30 0.26 0.48 0.55 0.09

Gain Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Net Debt Paydown Yield % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.57 0.48 0.37 0.09 0.04

GANX vs HYFT, ELTX, ANVS: Net Debt Paydown Yield % Comparison

For the Biotechnology subindustry, Gain Therapeutics's Net Debt Paydown Yield %, along with its competitors' market caps and Net Debt Paydown Yield % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Gain Therapeutics Net Debt Paydown Yield % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Gain Therapeutics's Net Debt Paydown Yield % distribution charts can be found below:

* The bar in red indicates where Gain Therapeutics's Net Debt Paydown Yield % falls into.


GANX
32GF Score
Gain Therapeutics Inc GANX
Net Debt Paydown Yield % is just one metric. See GF Score™, valuation, warning signs, and more.
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Gain Therapeutics Net Debt Paydown Yield % Calculation

Gain Therapeutics's Net Debt Paydown Yield % for the quarter that ended in Mar. 2026 is calculated as:

Net Debt Paydown Yield %
=( TTM Average Debt   (1-Year Ago))-TTM Average Debt )/Market Cap
=( 0.71-0.67 )/82.42866
=0.04 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

* All the data are calculated by TTM values. Note that if a companies is traded in several exchanges, then we calculate the company level data for Net Debt Paydown Yield % using the primary share class stock data. The calculation result in definition page is for demonstration purpose only, and it's showing the share class level data. Therefore, the numbers in the calculation may differ from elsewhere if the stock is not a primary share.

What does a Net Debt Paydown Yield % of 0.05% mean?
Gain Therapeutics (GANX) has a Net Debt Paydown Yield % of 0.05% as of Jul. 09, 2026. Net Debt Paydown Yield is a metric that evaluates the total amount of debt a company has paid in relation to its market capitalization. This metric provides insight into a company's willingness and ability to reduce its debt using free cash flow. View historical data on Gain Therapeutics and its competitors. This is 87% below median its historical median of 0.38. According to the industry distribution chart, Gain Therapeutics ranks #555 out of 1158 companies in the Biotechnology industry, placing it in the top 47.9%.
Is Gain Therapeutics' Net Debt Paydown Yield % too high?
Gain Therapeutics' current Net Debt Paydown Yield % of 0.05% is 87% below median its 10-year median of 0.38. The Biotechnology industry median Net Debt Paydown Yield % is 0.03. Gain Therapeutics' value of 0.05% is 66.7% above this industry median. Based on the distribution chart, Gain Therapeutics ranks #555 out of 1158 companies in the Biotechnology industry, which is above the industry midpoint. Overall, Gain Therapeutics has a GF Score™ of 32/100, reflecting its overall financial health beyond just this single metric.
How does Gain Therapeutics' Net Debt Paydown Yield % compare to HYFT and ELTX?
According to the Biotechnology industry distribution chart, Gain Therapeutics ranks #555 out of 1158 companies for Net Debt Paydown Yield %. This puts Gain Therapeutics in the upper half of its industry. The industry median Net Debt Paydown Yield % is 0.03. Gain Therapeutics' value of 0.05% is 66.7% above this benchmark. While the company's 10-year median is 0.38 vs. the industry median of 0.03, Gain Therapeutics has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Debt Paydown Yield % for a Biotechnology company?
The median Net Debt Paydown Yield % among Biotechnology companies is 0.03, based on 1,158 companies in the industry. Companies in the top quartile (top 25%) have a Net Debt Paydown Yield % significantly above this median, while those in the bottom quartile fall well below. However, Net Debt Paydown Yield % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Gain Therapeutics's current Net Debt Paydown Yield % of 0.05% is 66.7% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Debt Paydown Yield % mean?
A high Net Debt Paydown Yield % can signal that a stock is expensive relative to its fundamentals. Net Debt Paydown Yield is a metric that evaluates the total amount of debt a company has paid in relation to its market capitalization. This metric provides insight into a company's willingness and ability to reduce its debt using free cash flow. View historical data on Gain Therapeutics and its competitors. For the Biotechnology industry, the median Net Debt Paydown Yield % is 0.03 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Gain Therapeutics's current Net Debt Paydown Yield % is 0.05%, which is 87% below median its own 10-year median of 0.38. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Gain Therapeutics stock overvalued right now?
Gain Therapeutics (GANX) has a current Net Debt Paydown Yield % of 0.05%. The current Net Debt Paydown Yield % is 0.05%, which is 87% below median its 10-year median of 0.38 and 66.7% above the Biotechnology industry median of 0.03. Gain Therapeutics' overall GF Score™ is 32/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Debt Paydown Yield % calculated?
Net Debt Paydown Yield % is calculated from a company's financial statements. For Gain Therapeutics (GANX), the current Net Debt Paydown Yield % is 0.05% as of Jul. 09, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Gain Therapeutics Business Description

Address 4800 Montgomery Lane, Suite 220, Bethesda, MD, USA, 20814
Gain Therapeutics Inc is a clinical-stage biotechnology company developing novel small-molecule therapeutics to treat diseases across several therapeutic areas, including central nervous system (CNS) disorders, lysosomal storage disorders (LSDs), metabolic disorders, and other diseases that can be targeted through protein degradation, such as oncology. The Company's clinical stage product candidate, GT-02287, is being developed for the treatment of Parkinson's disease with and without GBA1 mutations. The Company generated an extensive preclinical data package providing evidence of the mechanism of action.
32GF Score

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