Scilex Holding Co (FRA:D8B0) Net Margin %: -502.40% (As of Mar. 2026)

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FRA:D8B0 Scilex Holding Co FRA:D8B0
39 GF Score
Price €6.40
GF Value €4.77
Valuation Significantly Overvalued
! 7 Warning Signs
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What is Scilex Holding Co Net Margin %?

Scilex Holding Co FRA:D8B0 -9.86% 39 Net Margin % is -502.40% as of Mar. 2026. GuruFocus rates FRA:D8B0 with a GF Score™ of 39/100 and a GF Value™ of €4.77 (Significantly Overvalued). The stock has 7 warning signs investors should review. Among 960 Drug Manufacturers companies, Scilex Holding Co ranks worse than 96.67% on this metric.

Net margin is calculated as Net Income divided by its Revenue. Scilex Holding Co's Net Income for the three months ended in Mar. 2026 was €-37.43 Mil. Scilex Holding Co's Revenue for the three months ended in Mar. 2026 was €7.45 Mil. Therefore, Scilex Holding Co's net margin for the quarter that ended in Mar. 2026 was -502.40%.

The historical rank and industry rank for Scilex Holding Co's Net Margin % or its related term are showing as below:

FRA:D8B0' s Net Margin % Range Over the Past 10 Years
Min: -1185.78   Med: -244.59   Max: -61.43
Current: -1110.17


FRA:D8B0's Net Margin % is ranked worse than
96.67% of 960 companies
in the Drug Manufacturers industry
Industry Median: 5.635 vs FRA:D8B0: -1110.17

Scilex Holding Co  (FRA:D8B0) Net Margin % Explanation

Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.

But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.


Scilex Holding Co Net Margin % Related Terms


Scilex Holding Co Net Margin % Historical Data

* Premium members only.

The historical data trend for Scilex Holding Co's Net Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Scilex Holding Co Net Margin % Chart

Scilex Holding Co Annual Data
Trend Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Net Margin %
Get a 7-Day Free Trial -282.35 -61.43 -244.60 -128.66 -1,185.78

Scilex Holding Co Quarterly Data
Dec20 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Net Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -521.15 -427.52 -2,435.96 -690.89 -502.40

FRA:D8B0 vs MIRA, NSRX, MDCX: Net Margin % Comparison

For the Drug Manufacturers - General subindustry, Scilex Holding Co's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Scilex Holding Co Net Margin % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Scilex Holding Co's Net Margin % distribution charts can be found below:

* The bar in red indicates where Scilex Holding Co's Net Margin % falls into.


FRA:D8B0
39GF Score
Scilex Holding Co FRA:D8B0
Net Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Scilex Holding Co Net Margin % Calculation

Net margin - also known as net profit margin is the ratio of Net Income divided by net sales or Revenue, usually presented in percent.

Scilex Holding Co's Net Margin for the fiscal year that ended in Dec. 2025 is calculated as

Net Margin=Net Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-306.359/25.836
=-1,185.78 %

Scilex Holding Co's Net Margin for the quarter that ended in Mar. 2026 is calculated as

Net Margin=Net Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-37.429/7.45
=-502.40 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Net Margin % →
What does a Net Margin % of -502.40% mean?
Scilex Holding Co (FRA:D8B0) has a Net Margin % of -502.40% as of Mar. 2026. Net margin is the ratio of total net income to net sales. View historical data on Scilex Holding Co and its competitors. According to the industry distribution chart, Scilex Holding Co ranks #928 out of 960 companies in the Drug Manufacturers industry, placing it in the top 96.7%.
Is Scilex Holding Co's Net Margin % too high?
Scilex Holding Co's current Net Margin % is -502.40%. Based on the distribution chart, Scilex Holding Co ranks #928 out of 960 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers. Overall, Scilex Holding Co has a GF Score™ of 39/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Scilex Holding Co's Net Margin % compare to MIRA and NSRX?
According to the Drug Manufacturers industry distribution chart, Scilex Holding Co ranks #928 out of 960 companies for Net Margin %. This places Scilex Holding Co in the lower half of its industry. The industry median Net Margin % is 5.64. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Drug Manufacturers company?
The median Net Margin % among Drug Manufacturers companies is 5.64, based on 960 companies in the industry. Companies in the top quartile (top 25%) have a Net Margin % significantly above this median, while those in the bottom quartile fall well below. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Scilex Holding Co and its competitors. For the Drug Manufacturers industry, the median Net Margin % is 5.64 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Scilex Holding Co's current Net Margin % is -502.40%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Scilex Holding Co stock overvalued right now?
Based on GuruFocus' analysis, Scilex Holding Co (FRA:D8B0) is currently considered Significantly Overvalued. The stock's GF Value™ is €4.77, compared to a current price of €6.40 — trading 34.2% above its estimated fair value. The current Net Margin % is -502.40%. Scilex Holding Co's overall GF Score™ is 39/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For Scilex Holding Co (FRA:D8B0), the current Net Margin % is -502.40% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Scilex Holding Co (FRA:D8B0) Overvalued in 2026?

Based on GuruFocus' analysis, Scilex Holding Co stock appears to be overvalued. The current stock price of €6.40 is trading 34.2% above its estimated GF Value™ of €4.77. GuruFocus considers Scilex Holding Co to be Significantly Overvalued.

Key valuation signals for FRA:D8B0:

  • Net Margin %: -502.40%
  • GF Value™: €4.77 vs. price of €6.40 (34.2% above fair value)
  • GF Score™: 39/100 with 7 warning signs

No single metric tells the full story. See the FRA:D8B0 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Scilex Holding Co Business Description

Other Exchanges SCLX:USA
Address 960 San Antonio Road, Palo Alto, CA, USA, 94303
Scilex Holding Co is focused on acquiring, developing and commercializing non-opioid pain management products for the treatment of acute and chronic pain. It targets indications with high unmet needs and large market opportunities with non-opioid therapies for the treatment of patients with acute and chronic pain and are dedicated to advancing and improving patient outcomes. Its commercial products are: ZTlidoO for the relief of neuropathic pain associated with postherpetic neuralgia (PHN), which is a form of post-shingles nerve pain; ELYXYB, a potential first-line treatment ready-to-use oral solution for the acute treatment of migraine in adults and GLOPERBA, the liquid oral version of the anti-gout medicine colchicine indicated for the prophylaxis of painful gout flares in adults.
39GF Score

Get the complete analysis for FRA:D8B0

Net Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€6.40
Price
€4.77
GF Value