Ligand Pharmaceuticals (FRA:LGDN) Net Margin %: -25.80% (As of Mar. 2026)


FRA:LGDN Ligand Pharmaceuticals Inc FRA:LGDN
78 GF Score
Price €270.00
GF Value €151.93
Valuation Significantly Overvalued
! 5 Warning Signs
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What is Ligand Pharmaceuticals Net Margin %?

Ligand Pharmaceuticals FRA:LGDN -0.74% 78 Net Margin % is -25.80% as of Mar. 2026. GuruFocus rates FRA:LGDN with a GF Score™ of 78/100 and a GF Value™ of €151.93 (Significantly Overvalued). The stock has 5 warning signs investors should review. Among 939 Biotechnology companies, Ligand Pharmaceuticals ranks better than 95.95% on this metric.

Net margin is calculated as Net Income divided by its Revenue. Ligand Pharmaceuticals's Net Income for the three months ended in Mar. 2026 was €-11.5 Mil. Ligand Pharmaceuticals's Revenue for the three months ended in Mar. 2026 was €44.7 Mil. Therefore, Ligand Pharmaceuticals's net margin for the quarter that ended in Mar. 2026 was -25.80%.

The historical rank and industry rank for Ligand Pharmaceuticals's Net Margin % or its related term are showing as below:

FRA:LGDN' s Net Margin % Range Over the Past 10 Years
Min: -17   Med: 16.28   Max: 523.19
Current: 55.95


FRA:LGDN's Net Margin % is ranked better than
95.95% of 939 companies
in the Biotechnology industry
Industry Median: -88.29 vs FRA:LGDN: 55.95

Ligand Pharmaceuticals  (FRA:LGDN) Net Margin % Explanation

Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.

But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.


Ligand Pharmaceuticals Net Margin % Related Terms


Ligand Pharmaceuticals Net Margin % Historical Data

* Premium members only.

The historical data trend for Ligand Pharmaceuticals's Net Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ligand Pharmaceuticals Net Margin % Chart

Ligand Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Net Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 23.66 -17.00 39.72 -2.41 46.42

Ligand Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Net Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -93.64 10.18 101.57 75.06 -25.80

FRA:LGDN vs DFTX, CGON, XENE: Net Margin % Comparison

For the Biotechnology subindustry, Ligand Pharmaceuticals's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Ligand Pharmaceuticals Net Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Ligand Pharmaceuticals's Net Margin % distribution charts can be found below:

* The bar in red indicates where Ligand Pharmaceuticals's Net Margin % falls into.


FRA:LGDN
78GF Score
Ligand Pharmaceuticals Inc FRA:LGDN
Net Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Ligand Pharmaceuticals Net Margin % Calculation

Net margin - also known as net profit margin is the ratio of Net Income divided by net sales or Revenue, usually presented in percent.

Ligand Pharmaceuticals's Net Margin for the fiscal year that ended in Dec. 2025 is calculated as

Net Margin=Net Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=106.283/228.946
=46.42 %

Ligand Pharmaceuticals's Net Margin for the quarter that ended in Mar. 2026 is calculated as

Net Margin=Net Income (Q: Mar. 2026 )/Revenue (Q: Mar. 2026 )
=-11.543/44.74
=-25.80 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Net Margin % →
What does a Net Margin % of -25.80% mean?
Ligand Pharmaceuticals (FRA:LGDN) has a Net Margin % of -25.80% as of Mar. 2026. Net margin is the ratio of total net income to net sales. View historical data on Ligand Pharmaceuticals and its competitors. According to the industry distribution chart, Ligand Pharmaceuticals ranks #38 out of 939 companies in the Biotechnology industry, placing it in the top 4%.
Is Ligand Pharmaceuticals' Net Margin % too high?
Ligand Pharmaceuticals' current Net Margin % is -25.80%. Based on the distribution chart, Ligand Pharmaceuticals ranks #38 out of 939 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Ligand Pharmaceuticals has a GF Score™ of 78/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Ligand Pharmaceuticals' Net Margin % compare to DFTX and CGON?
According to the Biotechnology industry distribution chart, Ligand Pharmaceuticals ranks #38 out of 939 companies for Net Margin %. This places Ligand Pharmaceuticals in the top 4% of its industry — outperforming the majority of peers. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Biotechnology company?
A good Net Margin % depends on the Biotechnology industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Ligand Pharmaceuticals and its competitors. Ligand Pharmaceuticals's current Net Margin % is -25.80%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ligand Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Ligand Pharmaceuticals (FRA:LGDN) is currently considered Significantly Overvalued. The stock's GF Value™ is €151.93, compared to a current price of €270.00 — trading 77.7% above its estimated fair value. The current Net Margin % is -25.80%. Ligand Pharmaceuticals' overall GF Score™ is 78/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For Ligand Pharmaceuticals (FRA:LGDN), the current Net Margin % is -25.80% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Ligand Pharmaceuticals (FRA:LGDN) Overvalued in 2026?

Based on GuruFocus' analysis, Ligand Pharmaceuticals stock appears to be overvalued. The current stock price of €270.00 is trading 77.7% above its estimated GF Value™ of €151.93. GuruFocus considers Ligand Pharmaceuticals to be Significantly Overvalued.

Key valuation signals for FRA:LGDN:

  • Net Margin %: -25.80%
  • GF Value™: €151.93 vs. price of €270.00 (77.7% above fair value)
  • GF Score™: 78/100 with 5 warning signs

No single metric tells the full story. See the FRA:LGDN stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Ligand Pharmaceuticals Business Description

Other Exchanges LGND:USA
Address 555 Heritage Drive, Suite 200, Jupiter, FL, USA, 33458
Ligand Pharmaceuticals Inc is a biopharmaceutical company focused on developing and acquiring technologies that aid in creating medicine. The company has partnerships and license agreements with various pharmaceutical and biotechnology companies. Ligand's business model is based on drug discovery, early-stage drug development, product reformulation, and partnerships. The company's revenue consists of three primary elements: royalties from commercialized products, license and milestone payments, and sale of its trademarked Captisol material.
78GF Score

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Net Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€270.00
Price
€151.93
GF Value