TransgeneFRA:TGNA -0.14%42 Net Margin % is -6,604.71% as of Dec. 2025. GuruFocus rates FRA:TGNA with a GF Score™ of 42/100 and a GF Value™ of €0.51 (Significantly Overvalued). The stock has 7 warning signs investors should review. Among 946 Biotechnology companies, Transgene ranks worse than 91.97% on this metric.
Net margin is calculated as Net Income divided by its Revenue. Transgene's Net Income for the
six
months ended in Dec. 2025 was €-18.23 Mil. Transgene's Revenue for the
six
months ended in Dec. 2025 was €0.28 Mil. Therefore, Transgene's net margin for the quarter that ended in Dec. 2025 was -6,604.71%.
The historical rank and industry rank for Transgene's Net Margin % or its related term are showing as below:
FRA:TGNA'
s Net Margin % Range Over the Past 10 Years
Min: -11065.47 Med: -1010.19 Max: 601.42
Current: -7657.96
FRA:TGNA's Net Margin % is ranked worse than 91.97% of 946
companies
in the Biotechnology industry
Industry Median: -88.815
vs FRA:TGNA: -7657.96
Transgene (FRA:TGNA) Net Margin % Explanation
Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.
But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.
Transgene Net Margin % Related Terms
Transgene Net Margin % Historical Data
* Premium members only.
The historical data trend for Transgene's Net Margin % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
FRA:TGNA vs VRTX, REGN, ALNY: Net Margin % Comparison
For the Biotechnology subindustry, Transgene's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Transgene Net Margin % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Transgene's Net Margin % distribution charts can be found below:
* The bar in red indicates where Transgene's Net Margin % falls into.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Transgene (FRA:TGNA) has a Net Margin % of -6,604.71% as of Dec. 2025. Net margin is the ratio of total net income to net sales. View historical data on Transgene and its competitors. According to the industry distribution chart, Transgene ranks #870 out of 946 companies in the Biotechnology industry, placing it in the top 92%.
Is Transgene's Net Margin % too high?
Transgene's current Net Margin % is -6,604.71%. Based on the distribution chart, Transgene ranks #870 out of 946 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Transgene has a GF Score™ of 42/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Transgene's Net Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Transgene ranks #870 out of 946 companies for Net Margin %. This places Transgene in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Biotechnology company?
A good Net Margin % depends on the Biotechnology industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Transgene and its competitors. Transgene's current Net Margin % is -6,604.71%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Transgene stock overvalued right now?
Based on GuruFocus' analysis, Transgene (FRA:TGNA) is currently considered Significantly Overvalued. The stock's GF Value™ is €0.51, compared to a current price of €0.70 — trading 37.8% above its estimated fair value. The current Net Margin % is -6,604.71%. Transgene's overall GF Score™ is 42/100 with 7 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For Transgene (FRA:TGNA), the current Net Margin % is -6,604.71% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Transgene (FRA:TGNA) Overvalued in 2026?
Based on GuruFocus' analysis, Transgene stock appears to be overvalued.
The current stock price of €0.70 is trading 37.8% above its estimated GF Value™ of €0.51.
GuruFocus considers Transgene to be Significantly Overvalued.
Key valuation signals for FRA:TGNA:
Net Margin %: -6,604.71%
GF Value™: €0.51 vs. price of €0.70 (37.8% above fair value)
No single metric tells the full story. See the FRA:TGNA stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Transgene SA is a biotechnology company that designs and develops virus based immunotherapy products focused on the development of individualized therapeutic vaccines against cancers. The flagship program, TG4050, is an individualized therapeutic vaccine based on the myvac platform. The company also has other viral vector-based programs, including BT-001, an oncolytic virus based on the Invir.IO viral backbone, which is in clinical development. In addition, it conducts discovery and preclinical work, aimed at developing novel immunotherapies.
42GF Score
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