ImmuneOnco Biopharmaceuticals (Shanghai) (HKSE:01541) Net Margin %: -56.76% (As of Dec. 2025)

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HKSE:01541 ImmuneOnco Biopharmaceuticals (Shanghai) Inc HKSE:01541
6 GF Score
Price HK$3.74
! 5 Warning Signs
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What is ImmuneOnco Biopharmaceuticals (Shanghai) Net Margin %?

ImmuneOnco Biopharmaceuticals (Shanghai) HKSE:01541 +6.71% 6 Net Margin % is -56.76% as of Dec. 2025. GuruFocus rates HKSE:01541 with a GF Score™ of 6/100. The stock has 5 warning signs investors should review. Among 944 Biotechnology companies, ImmuneOnco Biopharmaceuticals (Shanghai) ranks worse than 55.83% on this metric.

Net margin is calculated as Net Income divided by its Revenue. ImmuneOnco Biopharmaceuticals (Shanghai)'s Net Income for the six months ended in Dec. 2025 was HK$-72.9 Mil. ImmuneOnco Biopharmaceuticals (Shanghai)'s Revenue for the six months ended in Dec. 2025 was HK$128.4 Mil. Therefore, ImmuneOnco Biopharmaceuticals (Shanghai)'s net margin for the quarter that ended in Dec. 2025 was -56.76%.

The historical rank and industry rank for ImmuneOnco Biopharmaceuticals (Shanghai)'s Net Margin % or its related term are showing as below:

HKSE:01541' s Net Margin % Range Over the Past 10 Years
Min: -98351.66   Med: -14466.02   Max: -140.99
Current: -140.99


HKSE:01541's Net Margin % is ranked worse than
55.83% of 944 companies
in the Biotechnology industry
Industry Median: -85.875 vs HKSE:01541: -140.99

ImmuneOnco Biopharmaceuticals (Shanghai)  (HKSE:01541) Net Margin % Explanation

Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.

But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.


ImmuneOnco Biopharmaceuticals (Shanghai) Net Margin % Related Terms


ImmuneOnco Biopharmaceuticals (Shanghai) Net Margin % Historical Data

* Premium members only.

The historical data trend for ImmuneOnco Biopharmaceuticals (Shanghai)'s Net Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

ImmuneOnco Biopharmaceuticals (Shanghai) Net Margin % Chart

ImmuneOnco Biopharmaceuticals (Shanghai) Annual Data
Trend Dec21 Dec22 Dec23 Dec24 Dec25
Net Margin %
-14,466.02 -74,861.56 -98,351.66 -425.97 -141.67

ImmuneOnco Biopharmaceuticals (Shanghai) Semi-Annual Data
Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Net Margin % Get a 7-Day Free Trial Premium Member Only -69,571.34 -214,997.59 -202.63 -401.25 -56.76

HKSE:01541 vs VRTX, REGN, RVMD: Net Margin % Comparison

For the Biotechnology subindustry, ImmuneOnco Biopharmaceuticals (Shanghai)'s Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


ImmuneOnco Biopharmaceuticals (Shanghai) Net Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, ImmuneOnco Biopharmaceuticals (Shanghai)'s Net Margin % distribution charts can be found below:

* The bar in red indicates where ImmuneOnco Biopharmaceuticals (Shanghai)'s Net Margin % falls into.


HKSE:01541
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ImmuneOnco Biopharmaceuticals (Shanghai) Inc HKSE:01541
Net Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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ImmuneOnco Biopharmaceuticals (Shanghai) Net Margin % Calculation

Net margin - also known as net profit margin is the ratio of Net Income divided by net sales or Revenue, usually presented in percent.

ImmuneOnco Biopharmaceuticals (Shanghai)'s Net Margin for the fiscal year that ended in Dec. 2025 is calculated as

Net Margin=Net Income (A: Dec. 2025 )/Revenue (A: Dec. 2025 )
=-241.471/170.452
=-141.67 %

ImmuneOnco Biopharmaceuticals (Shanghai)'s Net Margin for the quarter that ended in Dec. 2025 is calculated as

Net Margin=Net Income (Q: Dec. 2025 )/Revenue (Q: Dec. 2025 )
=-72.905/128.443
=-56.76 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Net Margin % →
What does a Net Margin % of -56.76% mean?
ImmuneOnco Biopharmaceuticals (Shanghai) (HKSE:01541) has a Net Margin % of -56.76% as of Dec. 2025. Net margin is the ratio of total net income to net sales. View historical data on ImmuneOnco Biopharmaceuticals (Shanghai) and its competitors. According to the industry distribution chart, ImmuneOnco Biopharmaceuticals (Shanghai) ranks #527 out of 944 companies in the Biotechnology industry, placing it in the top 55.8%.
Is ImmuneOnco Biopharmaceuticals (Shanghai)'s Net Margin % too high?
ImmuneOnco Biopharmaceuticals (Shanghai)'s current Net Margin % is -56.76%. Based on the distribution chart, ImmuneOnco Biopharmaceuticals (Shanghai) ranks #527 out of 944 companies in the Biotechnology industry, which is below the industry midpoint. Overall, ImmuneOnco Biopharmaceuticals (Shanghai) has a GF Score™ of 6/100, reflecting its overall financial health beyond just this single metric.
How does ImmuneOnco Biopharmaceuticals (Shanghai)'s Net Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, ImmuneOnco Biopharmaceuticals (Shanghai) ranks #527 out of 944 companies for Net Margin %. This places ImmuneOnco Biopharmaceuticals (Shanghai) in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Biotechnology company?
A good Net Margin % depends on the Biotechnology industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on ImmuneOnco Biopharmaceuticals (Shanghai) and its competitors. ImmuneOnco Biopharmaceuticals (Shanghai)'s current Net Margin % is -56.76%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is ImmuneOnco Biopharmaceuticals (Shanghai) stock overvalued right now?
ImmuneOnco Biopharmaceuticals (Shanghai) (HKSE:01541) has a current Net Margin % of -56.76%. The current Net Margin % is -56.76%. ImmuneOnco Biopharmaceuticals (Shanghai)'s overall GF Score™ is 6/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For ImmuneOnco Biopharmaceuticals (Shanghai) (HKSE:01541), the current Net Margin % is -56.76% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

ImmuneOnco Biopharmaceuticals (Shanghai) Business Description

Address 1000 Zhangheng Road, Unit 15, China (Shanghai) Pilot Free Trade Zone, Pudong New Area, Shanghai, CHN
ImmuneOnco Biopharmaceuticals (Shanghai) Inc is a science-driven biotechnology company dedicated to the development of immuno-oncology therapies. It is one of the few biotechnology companies globally adopting a systematic approach to harness both the innate and adaptive immune systems. It has designed a robust pipeline of over ten drug candidates with 12 ongoing clinical programs., featured by a comprehensive innate-immunity-based asset portfolio. Its pipeline reflects its extensive understanding of the frontiers of cancer biology and immunology and its expertise in turning scientific research into drug candidates.
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