Physiomics (LSE:PYC) Net Margin %: -60.44% (As of Dec. 2025)


What is Physiomics Net Margin %?

Physiomics LSE:PYC -9.52% Net Margin % is -60.44% as of Dec. 2025. The stock has 6 warning signs investors should review. Among 947 Biotechnology companies, Physiomics ranks better than 55.12% on this metric.

Net margin is calculated as Net Income divided by its Revenue. Physiomics's Net Income for the six months ended in Dec. 2025 was £-0.30 Mil. Physiomics's Revenue for the six months ended in Dec. 2025 was £0.50 Mil. Therefore, Physiomics's net margin for the quarter that ended in Dec. 2025 was -60.44%.

The historical rank and industry rank for Physiomics's Net Margin % or its related term are showing as below:

LSE:PYC' s Net Margin % Range Over the Past 10 Years
Min: -182.27   Med: -47.85   Max: -8.01
Current: -50.89

LSE:PYC's Net Margin % is ranked better than
55.12% of 947 companies
in the Biotechnology industry
Industry Median: -89.33 vs LSE:PYC: -50.89

Physiomics  (LSE:PYC) Net Margin % Explanation

Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.

But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.

Physiomics Net Margin % Related Terms

Physiomics Net Margin % Historical Data

* Premium members only.

The historical data trend for Physiomics's Net Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Physiomics Net Margin % Chart

Physiomics Annual Data
Trend Jun16 Jun17 Jun18 Jun19 Jun20 Jun21 Jun22 Jun23 Jun24 Jun25
Net Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -30.77 -30.48 -79.90 -112.15 -52.93

Physiomics Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Net Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -55.08 -238.46 -70.21 -40.44 -60.44

LSE:PYC vs VRTX, REGN, ALNY: Net Margin % Comparison

For the Biotechnology subindustry, Physiomics's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Physiomics Net Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Physiomics's Net Margin % distribution charts can be found below:

* The bar in red indicates where Physiomics's Net Margin % falls into.


Physiomics Net Margin % Calculation

Net margin - also known as net profit margin is the ratio of Net Income divided by net sales or Revenue, usually presented in percent.

Physiomics's Net Margin for the fiscal year that ended in Jun. 2025 is calculated as

Net Margin=Net Income (A: Jun. 2025 )/Revenue (A: Jun. 2025 )
=-0.415/0.784
=-52.93 %

Physiomics's Net Margin for the quarter that ended in Dec. 2025 is calculated as

Net Margin=Net Income (Q: Dec. 2025 )/Revenue (Q: Dec. 2025 )
=-0.301/0.498
=-60.44 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Net Margin % →
What does a Net Margin % of -60.44% mean?
Physiomics (LSE:PYC) has a Net Margin % of -60.44% as of Dec. 2025. Net margin is the ratio of total net income to net sales. View historical data on Physiomics and its competitors. According to the industry distribution chart, Physiomics ranks #425 out of 947 companies in the Biotechnology industry, placing it in the top 44.9%.
Is Physiomics' Net Margin % too high?
Physiomics' current Net Margin % is -60.44%. Based on the distribution chart, Physiomics ranks #425 out of 947 companies in the Biotechnology industry, which is above the industry midpoint.
How does Physiomics' Net Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Physiomics ranks #425 out of 947 companies for Net Margin %. This puts Physiomics in the upper half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Net Margin % for a Biotechnology company?
A good Net Margin % depends on the Biotechnology industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Net Margin % mean?
A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Physiomics and its competitors. Physiomics's current Net Margin % is -60.44%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Physiomics stock overvalued right now?
Based on GuruFocus' analysis, Physiomics (LSE:PYC) is currently considered Possible Value Trap. The stock's GF Value™ is £0.01, compared to a current price of £0.00 — trading 52.5% below its estimated fair value. The current Net Margin % is -60.44%. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Net Margin % calculated?
Net Margin % is calculated from a company's financial statements. For Physiomics (LSE:PYC), the current Net Margin % is -60.44% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Physiomics Business Description

Other Exchanges RVW1:Germany
Address 140 Eastern Avenue, Bee House, Milton Park, Abingdon, GBR, OX14 4SB
Physiomics PLC is a United Kingdom-based firm that provides consulting services to biopharmaceutical companies and research institutes in the areas of outsourced modelling and simulation (quantitative pharmacology), biometrics, and data science (bioinformatics). Its business activities involve the use of industry-standard technologies and a proprietary technology platform called Virtual Tumour. The company has three service lines: Biometrics, Modelling and Simulation (Quantitative Pharmacology) and Personalised Medicine. It derives revenue from the UK, the European Union and Switzerland.