MIST (Milestone Pharmaceuticals) Net Margin %: -10,952.10% (As of Mar. 2026)

What is Milestone Pharmaceuticals Net Margin %?

Milestone Pharmaceuticals MIST -1.33% 26 Net Margin % is -10,952.10% as of Mar. 2026. GuruFocus rates MIST with a GF Score™ of 26/100. The stock has 6 warning signs investors should review. Among 946 Biotechnology companies, Milestone Pharmaceuticals ranks worse than 88.16% on this metric.

Net margin is calculated as Net Income divided by its Revenue. Milestone Pharmaceuticals's Net Income for the three months ended in Mar. 2026 was $-26.07 Mil. Milestone Pharmaceuticals's Revenue for the three months ended in Mar. 2026 was $0.24 Mil. Therefore, Milestone Pharmaceuticals's net margin for the quarter that ended in Mar. 2026 was -10,952.10%.

The historical rank and industry rank for Milestone Pharmaceuticals's Net Margin % or its related term are showing as below:

MIST' s Net Margin % Range Over the Past 10 Years
Min: -5968.5 Med: -2623.27 Max: -285.69
Current: -3832.01

MIST's Net Margin % is ranked worse than
88.16% of 946 companies
in the Biotechnology industry
Industry Median: -88.815 vs MIST: -3832.01

Milestone Pharmaceuticals (NAS:MIST) Net Margin % Explanation

Although Net Income and Earnings-per-Share (EPS) are the most widely used parameter in measuring a company's profitability and valuation, it is the least reliable. The reason is that reported earnings can be manipulated easily by adjusting any numbers such as Depreciation, Depletion and Amotorization and non-recurring items.

But the long term trend of the net margin is a good indicator of the competitiveness and health of the business.

Milestone Pharmaceuticals Net Margin % Related Terms

Milestone Pharmaceuticals Net Margin % Historical Data

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The historical data trend for Milestone Pharmaceuticals's Net Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Milestone Pharmaceuticals Net Margin % Chart

Milestone Pharmaceuticals Annual Data

Trend

Dec17

Dec18

Dec19

Dec20

Dec21

Dec22

Dec23

Dec24

Dec25

Net Margin %

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-285.69

-1,167.76

-5,968.50

0.00

-4,078.78

Milestone Pharmaceuticals Quarterly Data
	Jun21	Sep21	Dec21	Mar22	Jun22	Sep22	Dec22	Mar23	Jun23	Sep23	Dec23	Mar24	Jun24	Sep24	Dec24	Mar25	Jun25	Sep25	Dec25	Mar26
Net Margin %	Get a 7-Day Free Trial															0.00	0.00	0.00	-1,126.07	-10,952.10

MIST vs TLSA, DTIL, OKUR: Net Margin % Comparison

For the Biotechnology subindustry, Milestone Pharmaceuticals's Net Margin %, along with its competitors' market caps and Net Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.

Milestone Pharmaceuticals Net Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Milestone Pharmaceuticals's Net Margin % distribution charts can be found below:

* The bar in red indicates where Milestone Pharmaceuticals's Net Margin % falls into.

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26GF Score

Milestone Pharmaceuticals Inc MIST

Net Margin % is just one metric. See GF Score™, valuation, warning signs, and more.

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Milestone Pharmaceuticals Net Margin % Calculation

Net margin - also known as net profit margin is the ratio of Net Income divided by net sales or Revenue, usually presented in percent.

Milestone Pharmaceuticals's Net Margin for the fiscal year that ended in Dec. 2025 is calculated as

Net Margin	=	Net Income (A: Dec. 2025 )	/	Revenue (A: Dec. 2025 )
	=	-63.058	/	1.546
	=	-4,078.78 %

Milestone Pharmaceuticals's Net Margin for the quarter that ended in Mar. 2026 is calculated as

Net Margin	=	Net Income (Q: Mar. 2026 )	/	Revenue (Q: Mar. 2026 )
	=	-26.066	/	0.238
	=	-10,952.10 %

Frequently Asked Questions Learn more about Net Margin % →

What does a Net Margin % of -10,952.10% mean?

Milestone Pharmaceuticals (MIST) has a Net Margin % of -10,952.10% as of Mar. 2026. Net margin is the ratio of total net income to net sales. View historical data on Milestone Pharmaceuticals and its competitors. According to the industry distribution chart, Milestone Pharmaceuticals ranks #834 out of 946 companies in the Biotechnology industry, placing it in the top 88.2%.

Is Milestone Pharmaceuticals' Net Margin % too high?

Milestone Pharmaceuticals' current Net Margin % is -10,952.10%. Based on the distribution chart, Milestone Pharmaceuticals ranks #834 out of 946 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Milestone Pharmaceuticals has a GF Score™ of 26/100, reflecting its overall financial health beyond just this single metric.

How does Milestone Pharmaceuticals' Net Margin % compare to TLSA and DTIL?

According to the Biotechnology industry distribution chart, Milestone Pharmaceuticals ranks #834 out of 946 companies for Net Margin %. This places Milestone Pharmaceuticals in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.

What is a good Net Margin % for a Biotechnology company?

A good Net Margin % depends on the Biotechnology industry context. However, Net Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.

What does a high Net Margin % mean?

A high Net Margin % can signal that a stock is expensive relative to its fundamentals. Net margin is the ratio of total net income to net sales. View historical data on Milestone Pharmaceuticals and its competitors. Milestone Pharmaceuticals's current Net Margin % is -10,952.10%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.

Is Milestone Pharmaceuticals stock overvalued right now?

Milestone Pharmaceuticals (MIST) has a current Net Margin % of -10,952.10%. The current Net Margin % is -10,952.10%. Milestone Pharmaceuticals' overall GF Score™ is 26/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.

How is Net Margin % calculated?

Net Margin % is calculated from a company's financial statements. For Milestone Pharmaceuticals (MIST), the current Net Margin % is -10,952.10% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Milestone Pharmaceuticals Business Description

Industry Healthcare Biotechnology

Comparable Companies TLSA DTIL OKUR EQ PLX MDWD GALT PRQR QTTB ABOS VRTX REGN XBRU:UCB XBRU:ARGX XKRX:207940 ALNY RVMD ASX:CSL ONC XKRX:068270

Address 1111 Dr. Frederik-Phillips Boulevard, Suite 420, Montreal, QC, CAN, H4M 2X6

Website https://www.milestonepharma.com

Milestone Pharmaceuticals Inc is a biopharmaceutical company focused on the development and commercialization of cardiovascular medicines. Its approved product CARDAMYST (etripamil) nasal spray is available in the United States and is the self-administered treatment for use by patients anywhere, anytime an attack of PSVT occurs. It operates in single segment.

26GF Score

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