Agios Pharmaceuticals (FRA:8AP) OCF Yield %: -16.88 (As of Jun. 28, 2026)


FRA:8AP Agios Pharmaceuticals Inc FRA:8AP
44 GF Score
Price €31.00
GF Value €67.84
Valuation Possible Value Trap
! 4 Warning Signs
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What is Agios Pharmaceuticals OCF Yield %?

Agios Pharmaceuticals FRA:8AP -3.13% 44 OCF Yield % is -16.88 as of Jun. 28, 2026. GuruFocus rates FRA:8AP with a GF Score™ of 44/100 and a GF Value™ of €67.84 (Possible Value Trap). The stock has 4 warning signs investors should review. Among 1,417 Biotechnology companies, Agios Pharmaceuticals ranks worse than 65.07% on this metric.

OCF Yield % is calculated as Cash Flow from Operations divided by Market Capitalization. It is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

As of today, Agios Pharmaceuticals's Trailing 12-Month Cash Flow from Operations is €-327.00 Mil, and Market Cap is €1,983.92 Mil. Therefore, Agios Pharmaceuticals's OCF Yield % for today is -16.88%.

The historical rank and industry rank for Agios Pharmaceuticals's OCF Yield % or its related term are showing as below:

FRA:8AP' s OCF Yield % Range Over the Past 10 Years
Min: -39.2   Med: -12.4   Max: 6.05
Current: -16.88


During the past 13 years, the highest OCF Yield % of Agios Pharmaceuticals was 6.05%. The lowest was -39.20%. And the median was -12.40%.

FRA:8AP's OCF Yield % is ranked worse than
65.07% of 1417 companies
in the Biotechnology industry
Industry Median: -8.4 vs FRA:8AP: -16.88

Agios Pharmaceuticals's OCF Margin % for the quarter that ended in Mar. 2026 was %.


Agios Pharmaceuticals OCF Yield % Explanation

Similar to Earnings Yield %, OCF Yield % is financial solvency ratio. A lower ratio suggests a less attractive investment, indicating that investors might not receive substantial returns in proportion to their investment. Conversely, a high operating cash flow yield signals that a company generates sufficient cash to comfortably meet its debts, obligations, and dividend payments, making it a promising investment choice.


Agios Pharmaceuticals OCF Yield % Related Terms


Agios Pharmaceuticals OCF Yield % Historical Data

* Premium members only.

The historical data trend for Agios Pharmaceuticals's OCF Yield % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Agios Pharmaceuticals OCF Yield % Chart

Agios Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
OCF Yield %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -22.40 -20.90 -23.79 -20.61 -23.69

Agios Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
OCF Yield % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -25.82 -15.89 -15.53 -24.45 -26.88

FRA:8AP vs CAPR, SNDX, SLS: OCF Yield % Comparison

For the Biotechnology subindustry, Agios Pharmaceuticals's OCF Yield %, along with its competitors' market caps and OCF Yield % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Agios Pharmaceuticals OCF Yield % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Agios Pharmaceuticals's OCF Yield % distribution charts can be found below:

* The bar in red indicates where Agios Pharmaceuticals's OCF Yield % falls into.


FRA:8AP
44GF Score
Agios Pharmaceuticals Inc FRA:8AP
OCF Yield % is just one metric. See GF Score™, valuation, warning signs, and more.
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Agios Pharmaceuticals OCF Yield % Calculation

OCF Yield % is a financial solvency ratio that compares the operating cash flow a company is expected to earn against its market value.

Agios Pharmaceuticals's OCF Yield % for the fiscal year that ended in Dec. 2025 is calculated as

OCF Yield %=Cash Flow from Operations / Market Cap
=-318.522 / 1344.327
=-23.69%

Agios Pharmaceuticals's annualized OCF Yield % for the quarter that ended in Mar. 2026 is calculated as

OCF Yield %=Cash Flow from Operations * Annualized Factor / Market Cap
=-102.866 * 4 / 1530.9978
=-26.88%

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about OCF Yield % →
What does a OCF Yield % of -16.88 mean?
Agios Pharmaceuticals (FRA:8AP) has a OCF Yield % of -16.88 as of Jun. 28, 2026. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on Agios Pharmaceuticals and its competitors. According to the industry distribution chart, Agios Pharmaceuticals ranks #922 out of 1417 companies in the Biotechnology industry, placing it in the top 65.1%.
Is Agios Pharmaceuticals' OCF Yield % too high?
Agios Pharmaceuticals' current OCF Yield % is -16.88. Based on the distribution chart, Agios Pharmaceuticals ranks #922 out of 1417 companies in the Biotechnology industry, which is below the industry midpoint. Overall, Agios Pharmaceuticals has a GF Score™ of 44/100 and is considered Possible Value Trap, reflecting its overall financial health beyond just this single metric.
How does Agios Pharmaceuticals' OCF Yield % compare to CAPR and SNDX?
According to the Biotechnology industry distribution chart, Agios Pharmaceuticals ranks #922 out of 1417 companies for OCF Yield %. This places Agios Pharmaceuticals in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good OCF Yield % for a Biotechnology company?
A good OCF Yield % depends on the Biotechnology industry context. However, OCF Yield % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high OCF Yield % mean?
A high OCF Yield % can signal that a stock is expensive relative to its fundamentals. OCF Yield is calculated as Cash Flow from Operations divided by Market Capitalization. View historical data on Agios Pharmaceuticals and its competitors. Agios Pharmaceuticals's current OCF Yield % is -16.88. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Agios Pharmaceuticals stock overvalued right now?
Based on GuruFocus' analysis, Agios Pharmaceuticals (FRA:8AP) is currently considered Possible Value Trap. The stock's GF Value™ is €67.84, compared to a current price of €31.00 — trading 54.3% below its estimated fair value. The current OCF Yield % is -16.88. Agios Pharmaceuticals' overall GF Score™ is 44/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is OCF Yield % calculated?
OCF Yield % is calculated from a company's financial statements. For Agios Pharmaceuticals (FRA:8AP), the current OCF Yield % is -16.88 as of Jun. 28, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Agios Pharmaceuticals (FRA:8AP) Overvalued in 2026?

Based on GuruFocus' analysis, Agios Pharmaceuticals stock appears to be undervalued. The current stock price of €31.00 is trading 54.3% below its estimated GF Value™ of €67.84. GuruFocus considers Agios Pharmaceuticals to be Possible Value Trap.

Key valuation signals for FRA:8AP:

  • OCF Yield %: -16.88
  • GF Value™: €67.84 vs. price of €31.00 (54.3% below fair value)
  • GF Score™: 44/100 with 4 warning signs

No single metric tells the full story. See the FRA:8AP stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Agios Pharmaceuticals Business Description

Other Exchanges AGIO:USA0HB0:UK8AP:Germany
Address 88 Sidney Street, Cambridge, MA, USA, 02139
Agios Pharmaceuticals Inc is a biopharmaceutical company focused on the field of cellular metabolism to create differentiated medicines for rare diseases, with a focus on classical hematology. The company's primary focus is to develop potentially transformative small-molecule medicines. Its product candidate, Pyrukynd (mitapivat), is an activator of both wild-type and mutant pyruvate kinase enzymes, developed for the treatment of hemolytic anemias. The other drug candidates in its pipeline include Tebapivat (PK activator), being developed as a potential treatment for MDS-associated anemia and sickle cell disease, AG-181 (PAH stabilizer), AG-236 and others.
44GF Score

Get the complete analysis for FRA:8AP

OCF Yield % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€31.00
Price
€67.84
GF Value