BLSM (BlossomHill Therapeutics) Operating Margin %: 0.00% (As of Dec. 2025)

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BLSM BlossomHill Therapeutics Inc BLSM
8 GF Score
Price $16.02
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What is BlossomHill Therapeutics Operating Margin %?

BlossomHill Therapeutics BLSM -0.06% 8 Operating Margin % is 0.00% as of Dec. 2025. GuruFocus rates BLSM with a GF Score™ of 8/100. Among 942 Biotechnology companies, BlossomHill Therapeutics ranks worse than 106157.01% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. BlossomHill Therapeutics's Operating Income for the six months ended in Dec. 2025 was $-64.02 Mil. BlossomHill Therapeutics's Revenue for the six months ended in Dec. 2025 was $0.00 Mil. Therefore, BlossomHill Therapeutics's Operating Margin % for the quarter that ended in Dec. 2025 was 0.00%.

The historical rank and industry rank for BlossomHill Therapeutics's Operating Margin % or its related term are showing as below:


BLSM's Operating Margin % is not ranked *
in the Biotechnology industry.
Industry Median: -85.73
* Ranked among companies with meaningful Operating Margin % only.

BlossomHill Therapeutics's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

BlossomHill Therapeutics's Operating Income for the six months ended in Dec. 2025 was $-64.02 Mil.


BlossomHill Therapeutics  (NAS:BLSM) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


BlossomHill Therapeutics Operating Margin % Related Terms


BlossomHill Therapeutics Operating Margin % Historical Data

* Premium members only.

The historical data trend for BlossomHill Therapeutics's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

BlossomHill Therapeutics Operating Margin % Chart

BlossomHill Therapeutics Annual Data
Trend Dec24 Dec25
Operating Margin %
0.00 0.00

BlossomHill Therapeutics Semi-Annual Data
Dec24 Dec25
Operating Margin % 0.00 0.00

BLSM vs : Operating Margin % Comparison

For the Biotechnology subindustry, BlossomHill Therapeutics's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


BlossomHill Therapeutics Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, BlossomHill Therapeutics's Operating Margin % distribution charts can be found below:

* The bar in red indicates where BlossomHill Therapeutics's Operating Margin % falls into.


BLSM
8GF Score
BlossomHill Therapeutics Inc BLSM
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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BlossomHill Therapeutics Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

BlossomHill Therapeutics's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=-64.024 / 0
= %

BlossomHill Therapeutics's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=-64.024 / 0
= %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of 0.00% mean?
BlossomHill Therapeutics (BLSM) has a Operating Margin % of 0.00% as of Dec. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on BlossomHill Therapeutics and its competitors. According to the industry distribution chart, BlossomHill Therapeutics ranks #999999 out of 942 companies in the Biotechnology industry.
Is BlossomHill Therapeutics' Operating Margin % too high?
BlossomHill Therapeutics' current Operating Margin % is 0.00%. Based on the distribution chart, BlossomHill Therapeutics ranks #999999 out of 942 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, BlossomHill Therapeutics has a GF Score™ of 8/100, reflecting its overall financial health beyond just this single metric.
How does BlossomHill Therapeutics' Operating Margin % compare to ?
According to the Biotechnology industry distribution chart, BlossomHill Therapeutics ranks #999999 out of 942 companies for Operating Margin %. This places BlossomHill Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on BlossomHill Therapeutics and its competitors. BlossomHill Therapeutics's current Operating Margin % is 0.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is BlossomHill Therapeutics stock overvalued right now?
BlossomHill Therapeutics (BLSM) has a current Operating Margin % of 0.00%. The current Operating Margin % is 0.00%. BlossomHill Therapeutics' overall GF Score™ is 8/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For BlossomHill Therapeutics (BLSM), the current Operating Margin % is 0.00% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

BlossomHill Therapeutics Business Description

Comparable Companies
Address 10255 Science Center Drive, Suite 200, San Diego, CA, USA, 92121
BlossomHill Therapeutics Inc is a clinical-stage biopharmaceutical company applying its intentional, chemistry-based approach to develop small molecule medicines that address unmet medical needs in cancer treatment. Its product pipeline includes two clinical-stage programs: BH-30643, an investigational, non-covalent, macrocyclic, brain active, mutant-selective OMNI-EGFR inhibitor for the treatment of epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC), and BH-30236, an investigational macrocyclic CDC-like kinase (CLK) inhibitor being evaluated first in relapsed or refractory acute myeloid leukemia (R/R AML) and higher-risk myelodysplastic syndromes (HR-MDS), and the preclinical-stage product candidate BH-501284 targeting activated KRAS.
8GF Score

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Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$16.02
Price