COEP (Coeptis Therapeutics Holdings) Operating Margin %: -230.63% (As of Dec. 2025)


COEP Coeptis Therapeutics Holdings Inc COEP
12 GF Score
Price $16.40
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What is Coeptis Therapeutics Holdings Operating Margin %?

Coeptis Therapeutics Holdings COEP +1.52% 12 Operating Margin % is -230.63% as of Dec. 2025. GuruFocus rates COEP with a GF Score™ of 12/100. Among 945 Biotechnology companies, Coeptis Therapeutics Holdings ranks worse than 78.41% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Coeptis Therapeutics Holdings's Operating Income for the three months ended in Dec. 2025 was $-1.99 Mil. Coeptis Therapeutics Holdings's Revenue for the three months ended in Dec. 2025 was $0.86 Mil. Therefore, Coeptis Therapeutics Holdings's Operating Margin % for the quarter that ended in Dec. 2025 was -230.63%.

The historical rank and industry rank for Coeptis Therapeutics Holdings's Operating Margin % or its related term are showing as below:

COEP' s Operating Margin % Range Over the Past 10 Years
Min: -21654.84   Med: -18728   Max: -956.93
Current: -956.93


COEP's Operating Margin % is ranked worse than
78.41% of 945 companies
in the Biotechnology industry
Industry Median: -86.89 vs COEP: -956.93

Coeptis Therapeutics Holdings's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

Coeptis Therapeutics Holdings's Operating Income for the three months ended in Dec. 2025 was $-1.99 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Dec. 2025 was $-13.04 Mil.


Coeptis Therapeutics Holdings  (NAS:COEP) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Coeptis Therapeutics Holdings Operating Margin % Related Terms


Coeptis Therapeutics Holdings Operating Margin % Historical Data

* Premium members only.

The historical data trend for Coeptis Therapeutics Holdings's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Coeptis Therapeutics Holdings Operating Margin % Chart

Coeptis Therapeutics Holdings Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Operating Margin %
Get a 7-Day Free Trial -18,728.00 0.00 0.00 0.00 -956.93

Coeptis Therapeutics Holdings Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 -6,439.68 -2,249.25 -1,045.15 -230.63

COEP vs ANIX, COYA, PMN: Operating Margin % Comparison

For the Biotechnology subindustry, Coeptis Therapeutics Holdings's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Coeptis Therapeutics Holdings Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Coeptis Therapeutics Holdings's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Coeptis Therapeutics Holdings's Operating Margin % falls into.


COEP
12GF Score
Coeptis Therapeutics Holdings Inc COEP
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Coeptis Therapeutics Holdings Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Coeptis Therapeutics Holdings's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=-13.043 / 1.363
=-956.93 %

Coeptis Therapeutics Holdings's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=-1.988 / 0.862
=-230.63 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of -230.63% mean?
Coeptis Therapeutics Holdings (COEP) has a Operating Margin % of -230.63% as of Dec. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on Coeptis Therapeutics Holdings and its competitors. According to the industry distribution chart, Coeptis Therapeutics Holdings ranks #741 out of 945 companies in the Biotechnology industry, placing it in the top 78.4%.
Is Coeptis Therapeutics Holdings' Operating Margin % too high?
Coeptis Therapeutics Holdings' current Operating Margin % is -230.63%. Based on the distribution chart, Coeptis Therapeutics Holdings ranks #741 out of 945 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Coeptis Therapeutics Holdings has a GF Score™ of 12/100, reflecting its overall financial health beyond just this single metric.
How does Coeptis Therapeutics Holdings' Operating Margin % compare to ANIX and COYA?
According to the Biotechnology industry distribution chart, Coeptis Therapeutics Holdings ranks #741 out of 945 companies for Operating Margin %. This places Coeptis Therapeutics Holdings in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Coeptis Therapeutics Holdings and its competitors. Coeptis Therapeutics Holdings's current Operating Margin % is -230.63%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Coeptis Therapeutics Holdings stock overvalued right now?
Coeptis Therapeutics Holdings (COEP) has a current Operating Margin % of -230.63%. The current Operating Margin % is -230.63%. Coeptis Therapeutics Holdings' overall GF Score™ is 12/100. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Coeptis Therapeutics Holdings (COEP), the current Operating Margin % is -230.63% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Coeptis Therapeutics Holdings Business Description

Address 105 Bradford Road, Suite 420, Wexford, PA, USA, 15090
Coeptis Therapeutics Holdings Inc is a biopharmaceutical and technology company. The biopharmaceutical division focuses on developing cell therapy platforms for cancer, autoimmune, and infectious diseases. Coeptis aims to advance treatment paradigms and improve patient outcomes through its research and development efforts. The technology division focuses on enhancing operational capabilities through technologies. This division features AI-powered marketing software and robotic process automation tools designed to optimize business processes and improve overall efficiency. It derives the majority of the revenue from the Technology segment.
12GF Score

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