PfizerFRA:PFEB -2.16%74 Operating Margin % is 29.54% as of Mar. 2026, which is 19% above its 10-year median of 24.72. GuruFocus rates FRA:PFEB with a GF Score™ of 74/100 and a GF Value™ of €7.17 (Fairly Valued). The stock has 5 warning signs investors should review. Among 955 Drug Manufacturers companies, Pfizer ranks better than 92.04% on this metric.
Operating Margin % is calculated as Operating Income divided by its Revenue. Pfizer's Operating Income for the
three
months ended in Mar. 2026 was €3,692 Mil. Pfizer's Revenue for the
three
months ended in Mar. 2026 was €12,499 Mil. Therefore, Pfizer's Operating Margin % for the quarter that ended in Mar. 2026 was 29.54%.
Warning Sign:
Pfizer Inc operating margin has been in a 5-year decline. The average rate of decline per year is -3.6%.
The historical rank and industry rank for Pfizer's Operating Margin % or its related term are showing as below:
FRA:PFEB'
s Operating Margin % Range Over the Past 10 Years
Min: 7.42 Med: 24.72 Max: 37.67
Current: 27.24
FRA:PFEB's Operating Margin % is ranked better than 92.04% of 955
companies
in the Drug Manufacturers industry
Industry Median: 7.45
vs FRA:PFEB: 27.24
Pfizer's 5-Year Average Operating Margin % Growth Rate was -3.60% per year.
Pfizer's Operating Income for the
three
months ended in Mar. 2026 was €3,692 Mil.
Its Operating Income for the trailing twelve months (TTM) ended in Mar. 2026 was €14,816 Mil.
Pfizer (FRA:PFEB) Operating Margin % Explanation
Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.
Be Aware
Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).
If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.
For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokias Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).
Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.
Pfizer Operating Margin % Related Terms
Pfizer Operating Margin % Historical Data
* Premium members only.
The historical data trend for Pfizer's Operating Margin % can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
FRA:PFEB vs GILD, BMY, AMGN: Operating Margin % Comparison
For the Drug Manufacturers - General subindustry, Pfizer's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Pfizer Operating Margin % vs Drug Manufacturers Industry
For the Drug Manufacturers industry and Healthcare sector, Pfizer's Operating Margin % distribution charts can be found below:
* The bar in red indicates where Pfizer's Operating Margin % falls into.
Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.
Pfizer's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Pfizer (FRA:PFEB) has a Operating Margin % of 29.54% as of Mar. 2026. Operating margin is the ratio of total operating income to net sales. View historical data on Pfizer and its competitors. This is 19% above median its historical median of 24.72. Over the past decade, Pfizer's Operating Margin % has ranged from 7.42 to 37.67. According to the industry distribution chart, Pfizer ranks #76 out of 955 companies in the Drug Manufacturers industry, placing it in the top 8%.
Is Pfizer's Operating Margin % too high?
Pfizer's current Operating Margin % of 29.54% is 19% above median its 10-year median of 24.72. Over the past 10 years, this metric has ranged from a low of 7.42 to a high of 37.67. The Drug Manufacturers industry median Operating Margin % is 7.45. Pfizer's value of 29.54% is 296.5% above this industry median. Based on the distribution chart, Pfizer ranks #76 out of 955 companies in the Drug Manufacturers industry, which is in the top quartile — a strong position relative to peers. Overall, Pfizer has a GF Score™ of 74/100 and is considered Fairly Valued, reflecting its overall financial health beyond just this single metric.
How does Pfizer's Operating Margin % compare to GILD and BMY?
According to the Drug Manufacturers industry distribution chart, Pfizer ranks #76 out of 955 companies for Operating Margin %. This places Pfizer in the top 8% of its industry — outperforming the majority of peers. The industry median Operating Margin % is 7.45. Pfizer's value of 29.54% is 296.5% above this benchmark. Historically, Pfizer's own Operating Margin % has ranged from 7.42 to 37.67 over the past decade. While the company's 10-year median is 24.72 vs. the industry median of 7.45, Pfizer has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Drug Manufacturers company?
The median Operating Margin % among Drug Manufacturers companies is 7.45, based on 955 companies in the industry. Companies in the top quartile (top 25%) have a Operating Margin % significantly above this median, while those in the bottom quartile fall well below. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Pfizer's current Operating Margin % of 29.54% is 296.5% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Pfizer and its competitors. For the Drug Manufacturers industry, the median Operating Margin % is 7.45 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Pfizer's current Operating Margin % is 29.54%, which is 19% above median its own 10-year median of 24.72. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Pfizer stock overvalued right now?
Based on GuruFocus' analysis, Pfizer (FRA:PFEB) is currently considered Fairly Valued. The stock's GF Value™ is €7.17, compared to a current price of €6.80 — trading 5.2% below its estimated fair value. The current Operating Margin % is 29.54%, which is 19% above median its 10-year median of 24.72 and 296.5% above the Drug Manufacturers industry median of 7.45. Pfizer's overall GF Score™ is 74/100 with 5 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Pfizer (FRA:PFEB), the current Operating Margin % is 29.54% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Pfizer (FRA:PFEB) Overvalued in 2026?
Based on GuruFocus' analysis, Pfizer stock appears to be undervalued.
The current stock price of €6.80 is trading 5.2% below its estimated GF Value™ of €7.17.
GuruFocus considers Pfizer to be Fairly Valued.
Key valuation signals for FRA:PFEB:
Operating Margin %: 29.54% (19% above median its 10-year median of 24.72)
GF Value™: €7.17 vs. price of €6.80 (5.2% below fair value)
Industry Position: 296.5% above the Drug Manufacturers median (#76 of 955)
No single metric tells the full story. See the FRA:PFEB stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Pfizer is one of the world's largest pharmaceutical firms, with annual sales of roughly $60 billion. While it historically sold many types of healthcare products and chemicals, now prescription drugs and vaccines account for the majority of sales. Top sellers include pneumococcal vaccine Prevnar 13 and cardiology drugs Vyndaqel and Eliquis. Pfizer sells these products globally, with international sales representing 40% of total sales. Within international sales, emerging markets are a major contributor.
74GF Score
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