Allergy Therapeutics (LSE:AGY) Operating Margin %: -31.35% (As of Dec. 2025)


What is Allergy Therapeutics Operating Margin %?

Allergy Therapeutics LSE:AGY +6.86% Operating Margin % is -31.35% as of Dec. 2025. The stock has 7 warning signs investors should review. Among 955 Drug Manufacturers companies, Allergy Therapeutics ranks worse than 89.74% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Allergy Therapeutics's Operating Income for the six months ended in Dec. 2025 was £-11.38 Mil. Allergy Therapeutics's Revenue for the six months ended in Dec. 2025 was £36.28 Mil. Therefore, Allergy Therapeutics's Operating Margin % for the quarter that ended in Dec. 2025 was -31.35%.

The historical rank and industry rank for Allergy Therapeutics's Operating Margin % or its related term are showing as below:

LSE:AGY' s Operating Margin % Range Over the Past 10 Years
Min: -61.63   Med: -13.34   Max: 10.62
Current: -59.02


LSE:AGY's Operating Margin % is ranked worse than
89.74% of 955 companies
in the Drug Manufacturers industry
Industry Median: 7.45 vs LSE:AGY: -59.02

Allergy Therapeutics's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

Allergy Therapeutics's Operating Income for the six months ended in Dec. 2025 was £-11.38 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Dec. 2025 was £-33.81 Mil.

Warning Sign:

Allergy Therapeutics PLC has never been profitable in the past 3 years. It lost money every year.


Allergy Therapeutics  (LSE:AGY) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Allergy Therapeutics Operating Margin % Related Terms


Allergy Therapeutics Operating Margin % Historical Data

* Premium members only.

The historical data trend for Allergy Therapeutics's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Allergy Therapeutics Operating Margin % Chart

Allergy Therapeutics Annual Data
Trend Jun16 Jun17 Jun18 Jun19 Jun20 Jun21 Jun22 Jun23 Jun24 Jun25
Operating Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 4.78 -16.83 -58.58 -61.63 -51.16

Allergy Therapeutics Semi-Annual Data
Jun16 Dec16 Jun17 Dec17 Jun18 Dec18 Jun19 Dec19 Jun20 Dec20 Jun21 Dec21 Jun22 Dec22 Jun23 Dec23 Jun24 Dec24 Jun25 Dec25
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -35.40 -102.34 -16.82 -106.78 -31.35

LSE:AGY vs ZTS, UTHR, VTRS: Operating Margin % Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Allergy Therapeutics's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Allergy Therapeutics Operating Margin % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Allergy Therapeutics's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Allergy Therapeutics's Operating Margin % falls into.



Allergy Therapeutics Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Allergy Therapeutics's Operating Margin % for the fiscal year that ended in Jun. 2025 is calculated as

Operating Margin %=Operating Income (A: Jun. 2025 ) / Revenue (A: Jun. 2025 )
=-28.162 / 55.044
=-51.16 %

Allergy Therapeutics's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=-11.375 / 36.28
=-31.35 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of -31.35% mean?
Allergy Therapeutics (LSE:AGY) has a Operating Margin % of -31.35% as of Dec. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on Allergy Therapeutics and its competitors. According to the industry distribution chart, Allergy Therapeutics ranks #857 out of 955 companies in the Drug Manufacturers industry, placing it in the top 89.7%.
Is Allergy Therapeutics' Operating Margin % too high?
Allergy Therapeutics' current Operating Margin % is -31.35%. Based on the distribution chart, Allergy Therapeutics ranks #857 out of 955 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers.
How does Allergy Therapeutics' Operating Margin % compare to ZTS and UTHR?
According to the Drug Manufacturers industry distribution chart, Allergy Therapeutics ranks #857 out of 955 companies for Operating Margin %. This places Allergy Therapeutics in the lower half of its industry. The industry median Operating Margin % is 7.45. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Drug Manufacturers company?
The median Operating Margin % among Drug Manufacturers companies is 7.45, based on 955 companies in the industry. Companies in the top quartile (top 25%) have a Operating Margin % significantly above this median, while those in the bottom quartile fall well below. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Allergy Therapeutics and its competitors. For the Drug Manufacturers industry, the median Operating Margin % is 7.45 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Allergy Therapeutics's current Operating Margin % is -31.35%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Allergy Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Allergy Therapeutics (LSE:AGY) is currently considered Significantly Overvalued. The stock's GF Value™ is £0.03, compared to a current price of £0.07 — trading 149.3% above its estimated fair value. The current Operating Margin % is -31.35%. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Allergy Therapeutics (LSE:AGY), the current Operating Margin % is -31.35% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Allergy Therapeutics Business Description

Other Exchanges AGYTF:USAHHU:Germany
Address Dominion Way, Worthing, West Sussex, GBR, BN14 8SA
Allergy Therapeutics plc is an international biotechnology group focused on the diagnosis and treatment of allergic disorders through immunotherapies that target the underlying cause of disease. Its portfolio includes Pollinex, Pollinex Quattro, Acarovac, Tyrosine S/TU, Venomil, Oralvac and other allergy immunotherapy products, supported by R&D programmes such as Grass MATA MPL and VLP Peanut. The Group operates in a single class of business, being the manufacture and sale of allergy-related medicines, and maintains centralised manufacturing and research and development capabilities in the UK. Its geographical presence covers Central Europe (Germany, Austria, Switzerland and the Netherlands), Southern Europe (Spain and Italy) and the Rest of the World (including the UK).