NMLSF (Restart Life Sciences) Operating Margin %: -232.65% (As of Mar. 2026)


What is Restart Life Sciences Operating Margin %?

Restart Life Sciences NMLSF Operating Margin % is -232.65% as of Mar. 2026. The stock has 3 warning signs investors should review. Among 944 Biotechnology companies, Restart Life Sciences ranks worse than 75% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Restart Life Sciences's Operating Income for the three months ended in Mar. 2026 was $-0.23 Mil. Restart Life Sciences's Revenue for the three months ended in Mar. 2026 was $0.10 Mil. Therefore, Restart Life Sciences's Operating Margin % for the quarter that ended in Mar. 2026 was -232.65%.

The historical rank and industry rank for Restart Life Sciences's Operating Margin % or its related term are showing as below:

NMLSF' s Operating Margin % Range Over the Past 10 Years
Min: -17457.14   Med: -16919.48   Max: -720.74
Current: -720.74


NMLSF's Operating Margin % is ranked worse than
75% of 944 companies
in the Biotechnology industry
Industry Median: -86.83 vs NMLSF: -720.74

Restart Life Sciences's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

Restart Life Sciences's Operating Income for the three months ended in Mar. 2026 was $-0.23 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Mar. 2026 was $-0.71 Mil.


Restart Life Sciences  (OTCPK:NMLSF) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Restart Life Sciences Operating Margin % Related Terms


Restart Life Sciences Operating Margin % Historical Data

* Premium members only.

The historical data trend for Restart Life Sciences's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Restart Life Sciences Operating Margin % Chart

Restart Life Sciences Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Operating Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 0.00

Restart Life Sciences Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 0.00 0.00 0.00 -232.65

NMLSF vs VRTX, REGN, ALNY: Operating Margin % Comparison

For the Biotechnology subindustry, Restart Life Sciences's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Restart Life Sciences Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Restart Life Sciences's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Restart Life Sciences's Operating Margin % falls into.



Restart Life Sciences Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Restart Life Sciences's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=-0.975 / 0
= %

Restart Life Sciences's Operating Margin % for the quarter that ended in Mar. 2026 is calculated as

Operating Margin %=Operating Income (Q: Mar. 2026 ) / Revenue (Q: Mar. 2026 )
=-0.228 / 0.098
=-232.65 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of -232.65% mean?
Restart Life Sciences (NMLSF) has a Operating Margin % of -232.65% as of Mar. 2026. Operating margin is the ratio of total operating income to net sales. View historical data on Restart Life Sciences and its competitors. According to the industry distribution chart, Restart Life Sciences ranks #708 out of 944 companies in the Biotechnology industry, placing it in the top 75%.
Is Restart Life Sciences' Operating Margin % too high?
Restart Life Sciences' current Operating Margin % is -232.65%. Based on the distribution chart, Restart Life Sciences ranks #708 out of 944 companies in the Biotechnology industry, which is below the industry midpoint.
How does Restart Life Sciences' Operating Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Restart Life Sciences ranks #708 out of 944 companies for Operating Margin %. This places Restart Life Sciences in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Restart Life Sciences and its competitors. Restart Life Sciences's current Operating Margin % is -232.65%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Restart Life Sciences stock overvalued right now?
Restart Life Sciences (NMLSF) has a current Operating Margin % of -232.65%. The current Operating Margin % is -232.65%. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Restart Life Sciences (NMLSF), the current Operating Margin % is -232.65% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Restart Life Sciences Business Description

Other Exchanges HEAL:Canada
Address 700 - 838 West Hastings Street, Vancouver, BC, CAN, V6C 0A6
Restart Life Sciences Corp is a Canadian-based life sciences company dedicated to addressing health challenges with wellness solutions. Its brands include HolyCrap, BrainQ, Brain Balls.