PLSH (Panacea Life Sciences Holdings) Operating Margin %: -340.00% (As of Sep. 2025)


What is Panacea Life Sciences Holdings Operating Margin %?

Panacea Life Sciences Holdings PLSH +3.64% Operating Margin % is -340.00% as of Sep. 2025. The stock has 6 warning signs investors should review. Among 955 Drug Manufacturers companies, Panacea Life Sciences Holdings ranks worse than 93.09% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Panacea Life Sciences Holdings's Operating Income for the three months ended in Sep. 2025 was $-0.17 Mil. Panacea Life Sciences Holdings's Revenue for the three months ended in Sep. 2025 was $0.05 Mil. Therefore, Panacea Life Sciences Holdings's Operating Margin % for the quarter that ended in Sep. 2025 was -340.00%.

The historical rank and industry rank for Panacea Life Sciences Holdings's Operating Margin % or its related term are showing as below:

PLSH' s Operating Margin % Range Over the Past 10 Years
Min: -347.39   Med: -250.74   Max: -58.31
Current: -160.28


PLSH's Operating Margin % is ranked worse than
93.09% of 955 companies
in the Drug Manufacturers industry
Industry Median: 7.45 vs PLSH: -160.28

Panacea Life Sciences Holdings's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

Panacea Life Sciences Holdings's Operating Income for the three months ended in Sep. 2025 was $-0.17 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Sep. 2025 was $-1.38 Mil.

Warning Sign:

Panacea Life Sciences Holdings Inc has never been profitable in the past 3 years. It lost money every year.


Panacea Life Sciences Holdings  (OTCPK:PLSH) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Panacea Life Sciences Holdings Operating Margin % Related Terms


Panacea Life Sciences Holdings Operating Margin % Historical Data

* Premium members only.

The historical data trend for Panacea Life Sciences Holdings's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Panacea Life Sciences Holdings Operating Margin % Chart

Panacea Life Sciences Holdings Annual Data
Trend Dec20 Dec21 Dec22 Dec23
Operating Margin %
-58.31 -268.93 -347.39 -232.54

Panacea Life Sciences Holdings Quarterly Data
Sep20 Dec20 Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Mar25 Jun25 Sep25
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -85.52 -70.07 -82.72 -333.49 -340.00

PLSH vs NPHC, OWPC, CBDY: Operating Margin % Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, Panacea Life Sciences Holdings's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Panacea Life Sciences Holdings Operating Margin % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, Panacea Life Sciences Holdings's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Panacea Life Sciences Holdings's Operating Margin % falls into.



Panacea Life Sciences Holdings Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Panacea Life Sciences Holdings's Operating Margin % for the fiscal year that ended in Dec. 2023 is calculated as

Operating Margin %=Operating Income (A: Dec. 2023 ) / Revenue (A: Dec. 2023 )
=-5.546 / 2.385
=-232.54 %

Panacea Life Sciences Holdings's Operating Margin % for the quarter that ended in Sep. 2025 is calculated as

Operating Margin %=Operating Income (Q: Sep. 2025 ) / Revenue (Q: Sep. 2025 )
=-0.17 / 0.05
=-340.00 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of -340.00% mean?
Panacea Life Sciences Holdings (PLSH) has a Operating Margin % of -340.00% as of Sep. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on Panacea Life Sciences Holdings and its competitors. According to the industry distribution chart, Panacea Life Sciences Holdings ranks #889 out of 955 companies in the Drug Manufacturers industry, placing it in the top 93.1%.
Is Panacea Life Sciences Holdings' Operating Margin % too high?
Panacea Life Sciences Holdings' current Operating Margin % is -340.00%. Based on the distribution chart, Panacea Life Sciences Holdings ranks #889 out of 955 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers.
How does Panacea Life Sciences Holdings' Operating Margin % compare to NPHC and OWPC?
According to the Drug Manufacturers industry distribution chart, Panacea Life Sciences Holdings ranks #889 out of 955 companies for Operating Margin %. This places Panacea Life Sciences Holdings in the lower half of its industry. The industry median Operating Margin % is 7.45. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Drug Manufacturers company?
The median Operating Margin % among Drug Manufacturers companies is 7.45, based on 955 companies in the industry. Companies in the top quartile (top 25%) have a Operating Margin % significantly above this median, while those in the bottom quartile fall well below. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Panacea Life Sciences Holdings and its competitors. For the Drug Manufacturers industry, the median Operating Margin % is 7.45 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Panacea Life Sciences Holdings's current Operating Margin % is -340.00%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Panacea Life Sciences Holdings stock overvalued right now?
Panacea Life Sciences Holdings (PLSH) has a current Operating Margin % of -340.00%. The current Operating Margin % is -340.00%. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Panacea Life Sciences Holdings (PLSH), the current Operating Margin % is -340.00% as of Sep. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Panacea Life Sciences Holdings Business Description

Address 5910 South University Boulevard, C18-193, Greenwood Village, CO, USA, 80121
Panacea Life Sciences Holdings Inc is a holding company organized as a plant-based natural health ingredient and product company, specializing in the development, manufacturing, research, and distribution of products and rapidly growing natural health and wellness market segment for both humans and animals. The company also offers the purest natural remedies within its branded product lines for every aspect of life: PANA Health, PANA Beauty, PANA Sport, PANA Pet, PANA Pure and PANA Life.