Syngen Biotech Co (ROCO:8279) Operating Margin %: 8.34% (As of Dec. 2025) — 51% Below Median

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

ROCO:8279 Syngen Biotech Co Ltd ROCO:8279
89 GF Score
Price NT$88.50
GF Value NT$158.16
Valuation Significantly Undervalued
! 2 Warning Signs
View Full Analysis

What is Syngen Biotech Co Operating Margin %?

Syngen Biotech Co ROCO:8279 +1.03% 89 Operating Margin % is 8.34% as of Dec. 2025, which is 51% below its 10-year median of 17.04. GuruFocus rates ROCO:8279 with a GF Score™ of 89/100 and a GF Value™ of NT$158.16 (Significantly Undervalued). The stock has 2 warning signs investors should review. Among 940 Biotechnology companies, Syngen Biotech Co ranks better than 84.68% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Syngen Biotech Co's Operating Income for the three months ended in Dec. 2025 was NT$40 Mil. Syngen Biotech Co's Revenue for the three months ended in Dec. 2025 was NT$480 Mil. Therefore, Syngen Biotech Co's Operating Margin % for the quarter that ended in Dec. 2025 was 8.34%.

Warning Sign:

Syngen Biotech Co Ltd operating margin has been in a 5-year decline. The average rate of decline per year is -6%.

The historical rank and industry rank for Syngen Biotech Co's Operating Margin % or its related term are showing as below:

ROCO:8279' s Operating Margin % Range Over the Past 10 Years
Min: 15.05   Med: 17.04   Max: 19.69
Current: 15.16


ROCO:8279's Operating Margin % is ranked better than
84.68% of 940 companies
in the Biotechnology industry
Industry Median: -86.19 vs ROCO:8279: 15.16

Syngen Biotech Co's 5-Year Average Operating Margin % Growth Rate was -6.00% per year.

Syngen Biotech Co's Operating Income for the three months ended in Dec. 2025 was NT$40 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Dec. 2025 was NT$324 Mil.


Syngen Biotech Co  (ROCO:8279) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Syngen Biotech Co Operating Margin % Related Terms


Syngen Biotech Co Operating Margin % Historical Data

* Premium members only.

The historical data trend for Syngen Biotech Co's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Syngen Biotech Co Operating Margin % Chart

Syngen Biotech Co Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Operating Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 19.15 19.69 16.02 15.41 15.16

Syngen Biotech Co Quarterly Data
Mar21 Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 13.68 14.58 18.62 17.75 8.34

ROCO:8279 vs VRTX, REGN, ALNY: Operating Margin % Comparison

For the Biotechnology subindustry, Syngen Biotech Co's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Syngen Biotech Co Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Syngen Biotech Co's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Syngen Biotech Co's Operating Margin % falls into.


ROCO:8279
89GF Score
Syngen Biotech Co Ltd ROCO:8279
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Syngen Biotech Co Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Syngen Biotech Co's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=323.959 / 2136.484
=15.16 %

Syngen Biotech Co's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=39.994 / 479.78
=8.34 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of 8.34% mean?
Syngen Biotech Co (ROCO:8279) has a Operating Margin % of 8.34% as of Dec. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on Syngen Biotech Co and its competitors. This is 51% below median its historical median of 17.04. Over the past decade, Syngen Biotech Co's Operating Margin % has ranged from 15.05 to 19.69. According to the industry distribution chart, Syngen Biotech Co ranks #144 out of 940 companies in the Biotechnology industry, placing it in the top 15.3%.
Is Syngen Biotech Co's Operating Margin % too high?
Syngen Biotech Co's current Operating Margin % of 8.34% is 51% below median its 10-year median of 17.04. Over the past 10 years, this metric has ranged from a low of 15.05 to a high of 19.69. Based on the distribution chart, Syngen Biotech Co ranks #144 out of 940 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Syngen Biotech Co has a GF Score™ of 89/100 and is considered Significantly Undervalued, reflecting its overall financial health beyond just this single metric.
How does Syngen Biotech Co's Operating Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Syngen Biotech Co ranks #144 out of 940 companies for Operating Margin %. This places Syngen Biotech Co in the top 15% of its industry — outperforming the majority of peers. Historically, Syngen Biotech Co's own Operating Margin % has ranged from 15.05 to 19.69 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Syngen Biotech Co and its competitors. Syngen Biotech Co's current Operating Margin % is 8.34%, which is 51% below median its own 10-year median of 17.04. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Syngen Biotech Co stock overvalued right now?
Based on GuruFocus' analysis, Syngen Biotech Co (ROCO:8279) is currently considered Significantly Undervalued. The stock's GF Value™ is NT$158.16, compared to a current price of NT$88.50 — trading 44% below its estimated fair value. The current Operating Margin % is 8.34%, which is 51% below median its 10-year median of 17.04. Syngen Biotech Co's overall GF Score™ is 89/100 with 2 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Syngen Biotech Co (ROCO:8279), the current Operating Margin % is 8.34% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Syngen Biotech Co (ROCO:8279) Overvalued in 2026?

Based on GuruFocus' analysis, Syngen Biotech Co stock appears to be undervalued. The current stock price of NT$88.50 is trading 44% below its estimated GF Value™ of NT$158.16. GuruFocus considers Syngen Biotech Co to be Significantly Undervalued.

Key valuation signals for ROCO:8279:

  • Operating Margin %: 8.34% (51% below median its 10-year median of 17.04)
  • GF Value™: NT$158.16 vs. price of NT$88.50 (44% below fair value)
  • GF Score™: 89/100 with 2 warning signs

No single metric tells the full story. See the ROCO:8279 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Syngen Biotech Co Business Description

Address Building A, NO.154, Kai-Yuan Road, Xinying District, Tainan, TWN, 73055
Syngen Biotech Co Ltd is a biotechnology company. It is engaged in the manufacturing, sales, and trading of microbial pharmaceutical raw materials. It also provides the design and development of health food and biochemical nutrition. The company's products include pharmaceutical ingredients, nutritional ingredients, biology fermentation products, biology agriculture and aquaculture products.
89GF Score

Get the complete analysis for ROCO:8279

Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

NT$88.50
Price
NT$158.16
GF Value