Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
Shanghai Serum Bio Technology Co Ltd operating margin has been in a 5-year decline. The average rate of decline per year is -11.8%.
The historical rank and industry rank for Shanghai Serum Bio Technology Co's Operating Margin % or its related term are showing as below:
SHSE:688163'
s Operating Margin % Range Over the Past 10 Years
Min: 15.75 Med: 37.74 Max: 45.34
Current: 26.42
SHSE:688163's Operating Margin % is ranked better than 91.7% of 940
companies
in the Biotechnology industry
Industry Median: -86.855
vs SHSE:688163: 26.42
Shanghai Serum Bio Technology Co (SHSE:688163) Operating Margin % Explanation
Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.
Be Aware
Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).
If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.
For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokias Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).
Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.
Shanghai Serum Bio Technology Co Operating Margin % Related Terms
Shanghai Serum Bio Technology Co Operating Margin % Historical Data
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Shanghai Serum Bio Technology Co Operating Margin % Chart
SHSE:688163 vs VRTX, REGN, RVMD: Operating Margin % Comparison
For the Biotechnology subindustry, Shanghai Serum Bio Technology Co's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Shanghai Serum Bio Technology Co Operating Margin % vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Shanghai Serum Bio Technology Co's Operating Margin % distribution charts can be found below:
* The bar in red indicates where Shanghai Serum Bio Technology Co's Operating Margin % falls into.
Shanghai Serum Bio Technology Co Operating Margin % Calculation
Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
Shanghai Serum Bio Technology Co (SHSE:688163) has a Operating Margin % of -3.52% as of Mar. 2026. Operating margin is the ratio of total operating income to net sales. View historical data on Shanghai Serum Bio Technology Co and its competitors. Over the past decade, Shanghai Serum Bio Technology Co's Operating Margin % has ranged from 15.75 to 45.34. According to the industry distribution chart, Shanghai Serum Bio Technology Co ranks #78 out of 940 companies in the Biotechnology industry, placing it in the top 8.3%.
Is Shanghai Serum Bio Technology Co's Operating Margin % too high?
Shanghai Serum Bio Technology Co's current Operating Margin % is -3.52%. Over the past 10 years, this metric has ranged from a low of 15.75 to a high of 45.34. Based on the distribution chart, Shanghai Serum Bio Technology Co ranks #78 out of 940 companies in the Biotechnology industry, which is in the top quartile — a strong position relative to peers. Overall, Shanghai Serum Bio Technology Co has a GF Score™ of 71/100 and is considered Modestly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Shanghai Serum Bio Technology Co's Operating Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Shanghai Serum Bio Technology Co ranks #78 out of 940 companies for Operating Margin %. This places Shanghai Serum Bio Technology Co in the top 8% of its industry — outperforming the majority of peers. Historically, Shanghai Serum Bio Technology Co's own Operating Margin % has ranged from 15.75 to 45.34 over the past decade. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Shanghai Serum Bio Technology Co and its competitors. Shanghai Serum Bio Technology Co's current Operating Margin % is -3.52%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Shanghai Serum Bio Technology Co stock overvalued right now?
Based on GuruFocus' analysis, Shanghai Serum Bio Technology Co (SHSE:688163) is currently considered Modestly Overvalued. The stock's GF Value™ is ¥24.93, compared to a current price of ¥28.42 — trading 14% above its estimated fair value. The current Operating Margin % is -3.52%. Shanghai Serum Bio Technology Co's overall GF Score™ is 71/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Shanghai Serum Bio Technology Co (SHSE:688163), the current Operating Margin % is -3.52% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Is Shanghai Serum Bio Technology Co (SHSE:688163) Overvalued in 2026?
Based on GuruFocus' analysis, Shanghai Serum Bio Technology Co stock appears to be overvalued.
The current stock price of ¥28.42 is trading 14% above its estimated GF Value™ of ¥24.93.
GuruFocus considers Shanghai Serum Bio Technology Co to be Modestly Overvalued.
Key valuation signals for SHSE:688163:
Operating Margin %: -3.52%
GF Value™: ¥24.93 vs. price of ¥28.42 (14% above fair value)
No single metric tells the full story. See the SHSE:688163 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.
Shanghai Serum Bio Technology Co Business Description
Shanghai Serum Bio Technology Co Ltd is engaged in the research, development, production and sales of preventive and therapeutic drugs in the field of biotoxins and biosafety.
71GF Score
Get the complete analysis for SHSE:688163
Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
SHSE:688163 has been successfully added to your 
