Aligos Therapeutics (STU:5WK0) Operating Margin %: -951.55% (As of Mar. 2026)


STU:5WK0 Aligos Therapeutics Inc STU:5WK0
32 GF Score
Price €4.74
GF Value €2.38
Valuation Significantly Overvalued
! 4 Warning Signs
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What is Aligos Therapeutics Operating Margin %?

Aligos Therapeutics STU:5WK0 -1.25% 32 Operating Margin % is -951.55% as of Mar. 2026. GuruFocus rates STU:5WK0 with a GF Score™ of 32/100 and a GF Value™ of €2.38 (Significantly Overvalued). The stock has 4 warning signs investors should review. Among 943 Biotechnology companies, Aligos Therapeutics ranks worse than 84.62% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Aligos Therapeutics's Operating Income for the three months ended in Mar. 2026 was €-23.29 Mil. Aligos Therapeutics's Revenue for the three months ended in Mar. 2026 was €2.45 Mil. Therefore, Aligos Therapeutics's Operating Margin % for the quarter that ended in Mar. 2026 was -951.55%.

The historical rank and industry rank for Aligos Therapeutics's Operating Margin % or its related term are showing as below:

STU:5WK0' s Operating Margin % Range Over the Past 10 Years
Min: -4024.93   Med: -2259.92   Max: -567.5
Current: -2033.39


STU:5WK0's Operating Margin % is ranked worse than
84.62% of 943 companies
in the Biotechnology industry
Industry Median: -86.89 vs STU:5WK0: -2033.39

Aligos Therapeutics's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

Aligos Therapeutics's Operating Income for the three months ended in Mar. 2026 was €-23.29 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Mar. 2026 was €-82.19 Mil.


Aligos Therapeutics  (STU:5WK0) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Aligos Therapeutics Operating Margin % Related Terms


Aligos Therapeutics Operating Margin % Historical Data

* Premium members only.

The historical data trend for Aligos Therapeutics's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Aligos Therapeutics Operating Margin % Chart

Aligos Therapeutics Annual Data
Trend Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Operating Margin %
Get a 7-Day Free Trial -2,943.60 -701.68 -567.50 -2,260.21 -4,024.58

Aligos Therapeutics Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -6,180.56 -1,923.30 -3,829.48 -12,936.81 -951.55

STU:5WK0 vs LITS, ABVC, GRDX: Operating Margin % Comparison

For the Biotechnology subindustry, Aligos Therapeutics's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Aligos Therapeutics Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Aligos Therapeutics's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Aligos Therapeutics's Operating Margin % falls into.


STU:5WK0
32GF Score
Aligos Therapeutics Inc STU:5WK0
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Aligos Therapeutics Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Aligos Therapeutics's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=-75.139 / 1.867
=-4,024.58 %

Aligos Therapeutics's Operating Margin % for the quarter that ended in Mar. 2026 is calculated as

Operating Margin %=Operating Income (Q: Mar. 2026 ) / Revenue (Q: Mar. 2026 )
=-23.294 / 2.448
=-951.55 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of -951.55% mean?
Aligos Therapeutics (STU:5WK0) has a Operating Margin % of -951.55% as of Mar. 2026. Operating margin is the ratio of total operating income to net sales. View historical data on Aligos Therapeutics and its competitors. According to the industry distribution chart, Aligos Therapeutics ranks #798 out of 943 companies in the Biotechnology industry, placing it in the top 84.6%.
Is Aligos Therapeutics' Operating Margin % too high?
Aligos Therapeutics' current Operating Margin % is -951.55%. Based on the distribution chart, Aligos Therapeutics ranks #798 out of 943 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Aligos Therapeutics has a GF Score™ of 32/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Aligos Therapeutics' Operating Margin % compare to LITS and ABVC?
According to the Biotechnology industry distribution chart, Aligos Therapeutics ranks #798 out of 943 companies for Operating Margin %. This places Aligos Therapeutics in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Aligos Therapeutics and its competitors. Aligos Therapeutics's current Operating Margin % is -951.55%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Aligos Therapeutics stock overvalued right now?
Based on GuruFocus' analysis, Aligos Therapeutics (STU:5WK0) is currently considered Significantly Overvalued. The stock's GF Value™ is €2.38, compared to a current price of €4.74 — trading 99.2% above its estimated fair value. The current Operating Margin % is -951.55%. Aligos Therapeutics' overall GF Score™ is 32/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Aligos Therapeutics (STU:5WK0), the current Operating Margin % is -951.55% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Aligos Therapeutics (STU:5WK0) Overvalued in 2026?

Based on GuruFocus' analysis, Aligos Therapeutics stock appears to be overvalued. The current stock price of €4.74 is trading 99.2% above its estimated GF Value™ of €2.38. GuruFocus considers Aligos Therapeutics to be Significantly Overvalued.

Key valuation signals for STU:5WK0:

  • Operating Margin %: -951.55%
  • GF Value™: €2.38 vs. price of €4.74 (99.2% above fair value)
  • GF Score™: 32/100 with 4 warning signs

No single metric tells the full story. See the STU:5WK0 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Aligos Therapeutics Business Description

Other Exchanges ALGS:USA
Address One Corporate Drive, 2nd Floor, South San Francisco, CA, USA, 94080
Aligos Therapeutics Inc is a clinical-stage biotechnology company focused on developing therapeutics for liver diseases and viral infections. Its pipeline includes drug candidates targeting chronic hepatitis B virus (HBV) infection, metabolic dysfunction-associated steatohepatitis (MASH), obesity, and coronavirus infections, with programs such as pefivfoscorvir sodium for HBV, ALG-055009 for MASH and obesity, and ALG-097558 for coronavirus infections.
32GF Score

Get the complete analysis for STU:5WK0

Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€4.74
Price
€2.38
GF Value