SYMQY (SymBio Pharmaceuticals) Operating Margin %: -326.99% (As of Dec. 2025)


SYMQY SymBio Pharmaceuticals Ltd SYMQY
36 GF Score
Price $0.56
GF Value $0.51
! 6 Warning Signs
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What is SymBio Pharmaceuticals Operating Margin %?

SymBio Pharmaceuticals SYMQY -12.42% 36 Operating Margin % is -326.99% as of Dec. 2025. GuruFocus rates SYMQY with a GF Score™ of 36/100 and a GF Value™ of $0.51. The stock has 6 warning signs investors should review. Among 955 Drug Manufacturers companies, SymBio Pharmaceuticals ranks worse than 95.08% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. SymBio Pharmaceuticals's Operating Income for the three months ended in Dec. 2025 was $-7.06 Mil. SymBio Pharmaceuticals's Revenue for the three months ended in Dec. 2025 was $2.16 Mil. Therefore, SymBio Pharmaceuticals's Operating Margin % for the quarter that ended in Dec. 2025 was -326.99%.

The historical rank and industry rank for SymBio Pharmaceuticals's Operating Margin % or its related term are showing as below:

SYMQY' s Operating Margin % Range Over the Past 10 Years
Min: -439.49   Med: -102.21   Max: 19.62
Current: -439.49


SYMQY's Operating Margin % is ranked worse than
95.08% of 955 companies
in the Drug Manufacturers industry
Industry Median: 7.45 vs SYMQY: -439.49

SymBio Pharmaceuticals's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

SymBio Pharmaceuticals's Operating Income for the three months ended in Dec. 2025 was $-7.06 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Dec. 2025 was $-36.65 Mil.


SymBio Pharmaceuticals  (OTCPK:SYMQY) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


SymBio Pharmaceuticals Operating Margin % Related Terms


SymBio Pharmaceuticals Operating Margin % Historical Data

* Premium members only.

The historical data trend for SymBio Pharmaceuticals's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

SymBio Pharmaceuticals Operating Margin % Chart

SymBio Pharmaceuticals Annual Data
Trend Dec16 Dec17 Dec18 Dec19 Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Operating Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only 12.31 19.62 -14.52 -158.06 -339.59

SymBio Pharmaceuticals Quarterly Data
Jun21 Sep21 Dec21 Mar22 Jun22 Sep22 Dec22 Mar23 Jun23 Sep23 Dec23 Mar24 Jun24 Sep24 Dec24 Mar25 Jun25 Sep25 Dec25 Mar26
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only -442.91 -257.44 -365.74 -326.99 -1,002.92

SYMQY vs ZTS: Operating Margin % Comparison

For the Drug Manufacturers - Specialty & Generic subindustry, SymBio Pharmaceuticals's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


SymBio Pharmaceuticals Operating Margin % vs Drug Manufacturers Industry

For the Drug Manufacturers industry and Healthcare sector, SymBio Pharmaceuticals's Operating Margin % distribution charts can be found below:

* The bar in red indicates where SymBio Pharmaceuticals's Operating Margin % falls into.


SYMQY
36GF Score
SymBio Pharmaceuticals Ltd SYMQY
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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SymBio Pharmaceuticals Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

SymBio Pharmaceuticals's Operating Margin % for the fiscal year that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (A: Dec. 2025 ) / Revenue (A: Dec. 2025 )
=-28.481 / 8.387
=-339.59 %

SymBio Pharmaceuticals's Operating Margin % for the quarter that ended in Dec. 2025 is calculated as

Operating Margin %=Operating Income (Q: Dec. 2025 ) / Revenue (Q: Dec. 2025 )
=-7.063 / 2.16
=-326.99 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of -326.99% mean?
SymBio Pharmaceuticals (SYMQY) has a Operating Margin % of -326.99% as of Dec. 2025. Operating margin is the ratio of total operating income to net sales. View historical data on SymBio Pharmaceuticals and its competitors. According to the industry distribution chart, SymBio Pharmaceuticals ranks #908 out of 955 companies in the Drug Manufacturers industry, placing it in the top 95.1%.
Is SymBio Pharmaceuticals' Operating Margin % too high?
SymBio Pharmaceuticals' current Operating Margin % is -326.99%. Based on the distribution chart, SymBio Pharmaceuticals ranks #908 out of 955 companies in the Drug Manufacturers industry, which is in the bottom quartile relative to peers. Overall, SymBio Pharmaceuticals has a GF Score™ of 36/100, reflecting its overall financial health beyond just this single metric.
How does SymBio Pharmaceuticals' Operating Margin % compare to ZTS?
According to the Drug Manufacturers industry distribution chart, SymBio Pharmaceuticals ranks #908 out of 955 companies for Operating Margin %. This places SymBio Pharmaceuticals in the lower half of its industry. The industry median Operating Margin % is 7.45. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Drug Manufacturers company?
The median Operating Margin % among Drug Manufacturers companies is 7.45, based on 955 companies in the industry. Companies in the top quartile (top 25%) have a Operating Margin % significantly above this median, while those in the bottom quartile fall well below. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on SymBio Pharmaceuticals and its competitors. For the Drug Manufacturers industry, the median Operating Margin % is 7.45 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. SymBio Pharmaceuticals's current Operating Margin % is -326.99%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is SymBio Pharmaceuticals stock overvalued right now?
SymBio Pharmaceuticals (SYMQY) has a current Operating Margin % of -326.99%. The stock's GF Value™ is $0.51, compared to a current price of $0.56 — trading 9.4% above its estimated fair value. The current Operating Margin % is -326.99%. SymBio Pharmaceuticals' overall GF Score™ is 36/100 with 6 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For SymBio Pharmaceuticals (SYMQY), the current Operating Margin % is -326.99% as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is SymBio Pharmaceuticals (SYMQY) Overvalued in 2026?

Based on GuruFocus' analysis, SymBio Pharmaceuticals stock appears to be overvalued. The current stock price of $0.56 is trading 9.4% above its estimated GF Value™ of $0.51.

Key valuation signals for SYMQY:

  • Operating Margin %: -326.99%
  • GF Value™: $0.51 vs. price of $0.56 (9.4% above fair value)
  • GF Score™: 36/100 with 6 warning signs

No single metric tells the full story. See the SYMQY stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


SymBio Pharmaceuticals Business Description

Other Exchanges 4582:Japan
Address 1-28 Toranomon 4-chome, 7th Floor, Toranomon Towers Office, Minato-ku, Tokyo, JPN, 105-0001
SymBio Pharmaceuticals Ltd is a biopharmaceutical company engaged in development of new drugs with a primary focus on the treatment of rare diseases, mainly in the areas of oncology, hematology and multiple viral infections, and conduct integrated business activities that encompass search for new drug candidates, development, manufacturing, and sales.
36GF Score

Get the complete analysis for SYMQY

Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

$0.56
Price
$0.51
GF Value