Ribomic (TSE:4591) Operating Margin %: -22,296.77% (As of Mar. 2026)


TSE:4591 Ribomic Inc TSE:4591
30 GF Score
Price 円59.00
! 3 Warning Signs
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What is Ribomic Operating Margin %?

Ribomic TSE:4591 +1.72% 30 Operating Margin % is -22,296.77% as of Mar. 2026. GuruFocus rates TSE:4591 with a GF Score™ of 30/100. The stock has 3 warning signs investors should review. Among 943 Biotechnology companies, Ribomic ranks worse than 97.35% on this metric.

Operating Margin % is calculated as Operating Income divided by its Revenue. Ribomic's Operating Income for the six months ended in Mar. 2026 was 円-668.90 Mil. Ribomic's Revenue for the six months ended in Mar. 2026 was 円3.00 Mil. Therefore, Ribomic's Operating Margin % for the quarter that ended in Mar. 2026 was -22,296.77%.

The historical rank and industry rank for Ribomic's Operating Margin % or its related term are showing as below:

TSE:4591' s Operating Margin % Range Over the Past 10 Years
Min: -49861.84   Med: -2160.59   Max: -753.45
Current: -40237.73


TSE:4591's Operating Margin % is ranked worse than
97.35% of 943 companies
in the Biotechnology industry
Industry Median: -86.89 vs TSE:4591: -40237.73

Ribomic's 5-Year Average Operating Margin % Growth Rate was 0.00% per year.

Ribomic's Operating Income for the six months ended in Mar. 2026 was 円-668.90 Mil. Its Operating Income for the trailing twelve months (TTM) ended in Mar. 2026 was 円-1,207.13 Mil.


Ribomic  (TSE:4591) Operating Margin % Explanation

Just like Gross Margin %, it is important to see a company maintains its operating margin over time. Among the same industry, a company with higher operating margin is more efficient in its operation. It is also more stable during industry slowdown or recessions. Peter Lynch prefers those with higher margins than those with lower margins.


Be Aware

Operating Margin % can be manipulated by adjusting the rate of depreciation, depletion and amortization (DDA).

If a company is facing competition, its Operating Margin % may decline. Often the Operating Margin % declines well before the company's Revenue or even profit decline. Therefore, Operating Margin % is a very important indicator of whether the company is facing problems.

For instance, by 2012, Nokia (NOK)'s problems were well known and its stock had lost more than 90% of its market value since 2007. But Nokia’s Operating Margin % had already been in decline since 2002, although its Earnings per Share (Diluted) were still rising. Investors who paid attention to Operating Margin % would have avoided this huge loss. The same can be said for Research-in-Motion (RIMM).

Therefore, Operating Margin % is a very important screening filter for GuruFocus. GuruFocus's Buffett-Munger screener requires that the profit margin is either consistent or expanding. The Model Portfolio of the Buffett-Munger screener has outperformed the market every year since inception in 2009.


Ribomic Operating Margin % Related Terms


Ribomic Operating Margin % Historical Data

* Premium members only.

The historical data trend for Ribomic's Operating Margin % can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Ribomic Operating Margin % Chart

Ribomic Annual Data
Trend Mar17 Mar18 Mar19 Mar20 Mar21 Mar22 Mar23 Mar24 Mar25 Mar26
Operating Margin %
Get a 7-Day Free Trial Premium Member Only Premium Member Only -2,160.59 -2,707.39 0.00 -49,861.84 -40,237.73

Ribomic Semi-Annual Data
Sep16 Mar17 Sep17 Mar18 Sep18 Mar19 Sep19 Mar20 Sep20 Mar21 Sep21 Mar22 Sep22 Mar23 Sep23 Mar24 Sep24 Mar25 Sep25 Mar26
Operating Margin % Get a 7-Day Free Trial Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only Premium Member Only 0.00 -24,320.65 0.00 0.00 -22,296.77

TSE:4591 vs VRTX, REGN, ALNY: Operating Margin % Comparison

For the Biotechnology subindustry, Ribomic's Operating Margin %, along with its competitors' market caps and Operating Margin % data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Ribomic Operating Margin % vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Ribomic's Operating Margin % distribution charts can be found below:

* The bar in red indicates where Ribomic's Operating Margin % falls into.


TSE:4591
30GF Score
Ribomic Inc TSE:4591
Operating Margin % is just one metric. See GF Score™, valuation, warning signs, and more.
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Ribomic Operating Margin % Calculation

Operating Margin % - also known as operating income margin, operating profit margin and return on sales (ROS) - is the ratio of Operating Income divided by net sales or Revenue, usually presented in percent.

Ribomic's Operating Margin % for the fiscal year that ended in Mar. 2026 is calculated as

Operating Margin %=Operating Income (A: Mar. 2026 ) / Revenue (A: Mar. 2026 )
=-1207.132 / 3
=-40,237.73 %

Ribomic's Operating Margin % for the quarter that ended in Mar. 2026 is calculated as

Operating Margin %=Operating Income (Q: Mar. 2026 ) / Revenue (Q: Mar. 2026 )
=-668.903 / 3
=-22,296.77 %

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Frequently Asked Questions Learn more about Operating Margin % →
What does a Operating Margin % of -22,296.77% mean?
Ribomic (TSE:4591) has a Operating Margin % of -22,296.77% as of Mar. 2026. Operating margin is the ratio of total operating income to net sales. View historical data on Ribomic and its competitors. According to the industry distribution chart, Ribomic ranks #918 out of 943 companies in the Biotechnology industry, placing it in the top 97.3%.
Is Ribomic's Operating Margin % too high?
Ribomic's current Operating Margin % is -22,296.77%. Based on the distribution chart, Ribomic ranks #918 out of 943 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Ribomic has a GF Score™ of 30/100, reflecting its overall financial health beyond just this single metric.
How does Ribomic's Operating Margin % compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Ribomic ranks #918 out of 943 companies for Operating Margin %. This places Ribomic in the lower half of its industry. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Operating Margin % for a Biotechnology company?
A good Operating Margin % depends on the Biotechnology industry context. However, Operating Margin % should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Operating Margin % mean?
A high Operating Margin % can signal that a stock is expensive relative to its fundamentals. Operating margin is the ratio of total operating income to net sales. View historical data on Ribomic and its competitors. Ribomic's current Operating Margin % is -22,296.77%. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Ribomic stock overvalued right now?
Ribomic (TSE:4591) has a current Operating Margin % of -22,296.77%. The current Operating Margin % is -22,296.77%. Ribomic's overall GF Score™ is 30/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Operating Margin % calculated?
Operating Margin % is calculated from a company's financial statements. For Ribomic (TSE:4591), the current Operating Margin % is -22,296.77% as of Mar. 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Ribomic Business Description

Address 3-16-13 Usui Building, Shirokanedai, Minato-ku, Tokyo, JPN, 108-0071
Ribomic Inc is a biopharmaceutical venture company based in Tokyo. The company is developing molecular targeted pharmaceutical drugs using RNA aptamers with its unique and advanced platform technologies, the RiboART System.
30GF Score

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Operating Margin % is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

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