Biocytogen Pharmaceuticals (Beijing) Co (FRA:I54) Owner Earnings per Share (TTM): 0.04 (As of Dec. 2025)

Author: Vera Yuan Vera Yuan
Vera Yuan
Vera Yuan
Director of Data and Quant Analytics at GuruFocus
Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Reviewed by: Charlie Tian Charlie Tian
Charlie Tian
Charlie Tian
Founder & CEO of GuruFocus
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.

FRA:I54 Biocytogen Pharmaceuticals (Beijing) Co Ltd FRA:I54
72 GF Score
Price €6.35
GF Value €3.50
Valuation Significantly Overvalued
! 3 Warning Signs
View Full Analysis

What is Biocytogen Pharmaceuticals (Beijing) Co Owner Earnings per Share (TTM)?

Biocytogen Pharmaceuticals (Beijing) Co FRA:I54 +1.60% 72 Owner Earnings per Share (TTM) is 0.04 as of Dec. 2025. GuruFocus rates FRA:I54 with a GF Score™ of 72/100 and a GF Value™ of €3.50 (Significantly Overvalued). The stock has 3 warning signs investors should review. Among 213 Biotechnology companies, Biocytogen Pharmaceuticals (Beijing) Co ranks worse than 88.73% on this metric.

In 1986 Berkshire Hathaway Shareholder Letter, Warren Buffett defined owner earnings as follows:

"These represent (a) reported earnings plus (b) depreciation, depletion, amortization, and certain other non-cash charges...less (c) the average annual amount of capitalized expenditures for plant and equipment, etc. that the business requires to fully maintain its long-term competitive position and its unit volume (If the business requires additional working capital to maintain its competitive position and unit volume, the increment also should be included in (c))...Our owner-earnings equation does not yield the deceptively precise figures provided by GAAP, since (c) must be a guess - and one sometimes very difficult to make. Despite this problem, we consider the owner earnings figure, not the GAAP figure, to be the relevant item for valuation purposes - both for investors in buying stocks and for managers in buying entire businesses...All of this points up the absurdity of the 'cash flow' numbers that are often set forth in Wall Street reports. These numbers routinely include (a) plus (b) - but do not subtract (c)."

Biocytogen Pharmaceuticals (Beijing) Co's Owner Earnings per Share (TTM) ended in Dec. 2025 was €0.04. It's Price-to-Owner-Earnings ratio for today is 158.75.


The historical rank and industry rank for Biocytogen Pharmaceuticals (Beijing) Co's Owner Earnings per Share (TTM) or its related term are showing as below:

FRA:I54' s Price-to-Owner-Earnings Range Over the Past 10 Years
Min: 88.4   Med: 132.44   Max: 175.57
Current: 142.75


During the past 6 years, the highest Price-to-Owner-Earnings ratio of Biocytogen Pharmaceuticals (Beijing) Co was 175.57. The lowest was 88.40. And the median was 132.44.


FRA:I54's Price-to-Owner-Earnings is ranked worse than
88.73% of 213 companies
in the Biotechnology industry
Industry Median: 23.28 vs FRA:I54: 142.75

Biocytogen Pharmaceuticals (Beijing) Co's Earnings per Share (Diluted) for the six months ended in Jun. 2026 was €0.07. Its Earnings per Share (Diluted) for the trailing twelve months (TTM) ended in Jun. 2026 was €0.11. It's PE Ratio (TTM) ratio for today is 60.48.

Biocytogen Pharmaceuticals (Beijing) Co's EPS without NRI for the six months ended in Jun. 2026 was €0.06. Its EPS without NRI for the trailing twelve months (TTM) ended in Jun. 2026 was €0.09. It's PE Ratio without NRI ratio for today is 72.16.


Be Aware

Assumption: Companies usually do not report maintenance capital expenditures and growth capital expenditures separately. Here we use estimated numbers and average them over 5 years. The method to estimate maintenance capital expenditures can be found in above part 4.

Note: GuruFocus' Change In Working Capital is provided by FactSet. It is calculated by adding the items under "Change in operating assets and liabilities" (may refer to a different name for different company) section in Cash Flow Statement from original financial report. And it includes non-current parts of assets and liabilities.


Biocytogen Pharmaceuticals (Beijing) Co Owner Earnings per Share (TTM) Related Terms


Biocytogen Pharmaceuticals (Beijing) Co Owner Earnings per Share (TTM) Historical Data

* Premium members only.

The historical data trend for Biocytogen Pharmaceuticals (Beijing) Co's Owner Earnings per Share (TTM) can be seen below:

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

Biocytogen Pharmaceuticals (Beijing) Co Owner Earnings per Share (TTM) Chart

Biocytogen Pharmaceuticals (Beijing) Co Annual Data
Trend Dec20 Dec21 Dec22 Dec23 Dec24 Dec25
Owner Earnings per Share (TTM)
Get a 7-Day Free Trial 0.00 0.00 0.00 -0.03 0.04

Biocytogen Pharmaceuticals (Beijing) Co Semi-Annual Data
Dec21 Dec22 Dec23 Jun24 Dec24 Jun25 Dec25 Jun26
Owner Earnings per Share (TTM) Get a 7-Day Free Trial 0.00 0.00 0.00 0.00 0.00

FRA:I54 vs VRTX, REGN, MRNA: Owner Earnings per Share (TTM) Comparison

For the Biotechnology subindustry, Biocytogen Pharmaceuticals (Beijing) Co's Price-to-Owner-Earnings, along with its competitors' market caps and Price-to-Owner-Earnings data, can be viewed below:

* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.


Biocytogen Pharmaceuticals (Beijing) Co Price-to-Owner-Earnings vs Biotechnology Industry

For the Biotechnology industry and Healthcare sector, Biocytogen Pharmaceuticals (Beijing) Co's Price-to-Owner-Earnings distribution charts can be found below:

* The bar in red indicates where Biocytogen Pharmaceuticals (Beijing) Co's Price-to-Owner-Earnings falls into.


FRA:I54
72GF Score
Biocytogen Pharmaceuticals (Beijing) Co Ltd FRA:I54
Owner Earnings per Share (TTM) is just one metric. See GF Score™, valuation, warning signs, and more.
View Full Analysis

Biocytogen Pharmaceuticals (Beijing) Co Owner Earnings per Share (TTM) Calculation

In 1986 Berkshire Hathaway Shareholder Letter, Warren Buffett defined owner earnings as follows:

"These represent (a) reported earnings plus (b) depreciation, depletion, amortization, and certain other non-cash charges...less (c) the average annual amount of capitalized expenditures for plant and equipment, etc. that the business requires to fully maintain its long-term competitive position and its unit volume. (If the business requires additional working capital to maintain its competitive position and unit volume, the increment also should be included in (c))...Our owner-earnings equation does not yield the deceptively precise figures provided by GAAP, since (c) must be a guess - and one sometimes very difficult to make. Despite this problem, we consider the owner earnings figure, not the GAAP figure, to be the relevant item for valuation purposes - both for investors in buying stocks and for managers in buying entire businesses...All of this points up the absurdity of the 'cash flow' numbers that are often set forth in Wall Street reports. These numbers routinely include (a) plus (b) - but do not subtract (c)."

To make it simple, then you will have:

Owner Earnings per Share (TTM) = (Net Income + Depreciation, Depletion and Amortization + Change In Deferred Tax - 5Y Average of Maintenance Capital Expenditure + Change In Working Capital) / Shares Outstanding (Diluted Average)

Biocytogen Pharmaceuticals (Beijing) Co's Owner Earnings per Share (TTM) Calculation:

Last Year Average of Last 5 Years
Net Income 24.1
Depreciation, Depletion and Amortization 19.8
Change In Deferred Tax 0.0
5Y Average of Maintenance Capital Expenditure 18.4
Change In Working Capital -5.8
Shares Outstanding (Diluted Average) 400.1

1. Start with "Net Income" from income statement. Biocytogen Pharmaceuticals (Beijing) Co's Net Income for the trailing twelve months (TTM) ended in Dec. 2025 was €24.1 Mil.

2. "Depreciation, Depletion and Amortization" is from cashflow statement. Biocytogen Pharmaceuticals (Beijing) Co's Depreciation, Depletion and Amortization for the trailing twelve months (TTM) ended in Dec. 2025 was €19.8 Mil. This needs to be added back because company does not actually need to pay cash for it. It is a non-cash item.

3. Other non-cash charges usually include "Stock Based Compensation" and "Change In Deferred Tax":
However, to be conservative, GuruFocus will not add Stock Based Compensation back to net income. Biocytogen Pharmaceuticals (Beijing) Co's Change In Deferred Tax for the trailing twelve months (TTM) ended in Dec. 2025 was €0.0 Mil.

4. Average maintenance capital expenditure over a business/industry cycle: 5-Year Average Maintenance Capital Expenditure = €18.4 Mil

It is usually best to take a long-term average of maintenance capital expenditure. Ideally this would be as long as 10 years and include at least one economic downturn. However, since many companies do not have as long as 10-year history, here GuruFocus uses the latest 5 years data to do the calculation. To smooth out unusual years but reflect recent developments, we take an average of the 5 year maintenance capital expenditure.

The following shows how to get maintenance capital expenditure.

First, calculate the revenue change regarding to the previous year. If the revenue decreased from the previous year, then the Maintenance Capital Expenditure = Capital Expenditure (positive).
Second, if the revenue increased from the previous year, then calculate the percentage of Net PPE as of corresponding Revenue.
Growth Capital Expenditure = Percentage of Property, Plant and Equipment as of corresponding Revenue * Revenue Increase
Third, calculate Capital Expenditure (positive) - Growth Capital Expenditure.
If [Capital Expenditure (positive) - Growth Capital Expenditure] was negative, then the Maintenance Capital Expenditure = Capital Expenditure (positive).
If [Capital Expenditure (positive) - Growth Capital Expenditure] was positive, then the Maintenance Capital Expenditure = Capital Expenditure (positive) - Growth Capital Expenditure.
Fourth, get the average of the 5 years maintenance capital expenditure.

Biocytogen Pharmaceuticals (Beijing) Co's 5-Year Average Maintenance Capital Expenditure = €18.4 Mil

5. "Change In Working Capital" is from cashflow statement. Biocytogen Pharmaceuticals (Beijing) Co's Change In Working Capital for the trailing twelve months (TTM) ended in Dec. 2025 was €-5.8 Mil.
Note: GuruFocus' Change in Working Capital is provided by FactSet. It is calculated by adding the items under "Change in operating assets and liabilities" (may refer to a different name for different company) section in Cash Flow Statement from original financial report. And sometimes it includes non-current parts of assets and liabilities.

6. Biocytogen Pharmaceuticals (Beijing) Co's Shares Outstanding (Diluted Average) for the months ended in Dec. 2025 was 400.076 Mil.

Biocytogen Pharmaceuticals (Beijing) Co's Onwer Earnings Per Share for Dec. 2025 is calculated as:

Owner Earnings per Share (TTM)
=( Net Income+Depreciation, Depletion and Amortization+Change In Deferred Tax
=( 24.098564235589 +19.77856024201+0
-5Y Avg of Maintenance CAPEX+Change In Working Capital )/Shares Outstanding (Diluted Average)
-18.382+-5.8140767646057)/400.076
=0.04

Price-to-Owner-Earnings=Current Price/Owner Earnings per Share (TTM)
=6.35/0.04
=158.75

* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD.
* For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.

What does a Owner Earnings per Share (TTM) of 0.04 mean?
Biocytogen Pharmaceuticals (Beijing) Co (FRA:I54) has a Owner Earnings per Share (TTM) of 0.04 as of Dec. 2025. Warren Buffett defined owner earnings as reported earnings plus depreciation less average maintenance capital expenditure. View historical data on Biocytogen Pharmaceuticals (Beijing) Co. According to the industry distribution chart, Biocytogen Pharmaceuticals (Beijing) Co ranks #189 out of 213 companies in the Biotechnology industry, placing it in the top 88.7%.
Is Biocytogen Pharmaceuticals (Beijing) Co's Owner Earnings per Share (TTM) too high?
Biocytogen Pharmaceuticals (Beijing) Co's current Owner Earnings per Share (TTM) is 0.04. The Biotechnology industry median Owner Earnings per Share (TTM) is 23.28. Biocytogen Pharmaceuticals (Beijing) Co's value of 0.04 is 99.8% below this industry median. Based on the distribution chart, Biocytogen Pharmaceuticals (Beijing) Co ranks #189 out of 213 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Biocytogen Pharmaceuticals (Beijing) Co has a GF Score™ of 72/100 and is considered Significantly Overvalued, reflecting its overall financial health beyond just this single metric.
How does Biocytogen Pharmaceuticals (Beijing) Co's Owner Earnings per Share (TTM) compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Biocytogen Pharmaceuticals (Beijing) Co ranks #189 out of 213 companies for Owner Earnings per Share (TTM). This places Biocytogen Pharmaceuticals (Beijing) Co in the lower half of its industry. The industry median Owner Earnings per Share (TTM) is 23.28. Biocytogen Pharmaceuticals (Beijing) Co's value of 0.04 is 99.8% below this benchmark. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good Owner Earnings per Share (TTM) for a Biotechnology company?
The median Owner Earnings per Share (TTM) among Biotechnology companies is 23.28, based on 213 companies in the industry. Companies in the top quartile (top 25%) have a Owner Earnings per Share (TTM) significantly above this median, while those in the bottom quartile fall well below. However, Owner Earnings per Share (TTM) should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Biocytogen Pharmaceuticals (Beijing) Co's current Owner Earnings per Share (TTM) of 0.04 is 99.8% below the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high Owner Earnings per Share (TTM) mean?
A high Owner Earnings per Share (TTM) can signal that a stock is expensive relative to its fundamentals. Warren Buffett defined owner earnings as reported earnings plus depreciation less average maintenance capital expenditure. View historical data on Biocytogen Pharmaceuticals (Beijing) Co. For the Biotechnology industry, the median Owner Earnings per Share (TTM) is 23.28 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Biocytogen Pharmaceuticals (Beijing) Co's current Owner Earnings per Share (TTM) is 0.04. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Biocytogen Pharmaceuticals (Beijing) Co stock overvalued right now?
Based on GuruFocus' analysis, Biocytogen Pharmaceuticals (Beijing) Co (FRA:I54) is currently considered Significantly Overvalued. The stock's GF Value™ is €3.50, compared to a current price of €6.35 — trading 81.4% above its estimated fair value. The current Owner Earnings per Share (TTM) is 0.04 and 99.8% below the Biotechnology industry median of 23.28. Biocytogen Pharmaceuticals (Beijing) Co's overall GF Score™ is 72/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is Owner Earnings per Share (TTM) calculated?
Owner Earnings per Share (TTM) is calculated from a company's financial statements. For Biocytogen Pharmaceuticals (Beijing) Co (FRA:I54), the current Owner Earnings per Share (TTM) is 0.04 as of Dec. 2025. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.

Is Biocytogen Pharmaceuticals (Beijing) Co (FRA:I54) Overvalued in 2026?

Based on GuruFocus' analysis, Biocytogen Pharmaceuticals (Beijing) Co stock appears to be overvalued. The current stock price of €6.35 is trading 81.4% above its estimated GF Value™ of €3.50. GuruFocus considers Biocytogen Pharmaceuticals (Beijing) Co to be Significantly Overvalued.

Key valuation signals for FRA:I54:

  • Owner Earnings per Share (TTM): 0.04
  • GF Value™: €3.50 vs. price of €6.35 (81.4% above fair value)
  • GF Score™: 72/100 with 3 warning signs
  • Industry Position: 99.8% below the Biotechnology median (#189 of 213)

No single metric tells the full story. See the FRA:I54 stock analysis page for a complete view including 30-year financials, guru trades, and insider activity.


Biocytogen Pharmaceuticals (Beijing) Co Business Description

Other Exchanges 02315:Hong Kong688796:China
Address 12 Baoshen South Street, Daxing Bio-Medicine Industry Park, Daxing District, Beijing, CHN
Biocytogen Pharmaceuticals (Beijing) Co Ltd is a biopharmaceutical and pre-clinical research services company. It has two Core Products, YH003 and YH001. YH003 is a recombinant humanized agonistic anti-Cluster of Differentiation 40 (CD40) Immunoglobulin G2 (IgG2) monoclonal antibody and YH001 is a recombinant humanized anti-CTLA-4, a protein receptor expressed constitutively on T cells that functions as an immune checkpoint and downregulates immune responses, Immunoglobulin G1 (IgG1) monoclonal antibody. YH003 is being developed for pancreatic ductal adenocarcinoma, melanoma, and other developed solid tumors. YH001 is being developed for hepatocellular carcinoma (HCC), non-small-cell lung carcinoma (NSCLC), and other solid tumors.
72GF Score

Get the complete analysis for FRA:I54

Owner Earnings per Share (TTM) is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.

€6.35
Price
€3.50
GF Value