Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
Sareum HoldingsFRA:RYH0 36 PB Ratio is 21.80 as of Jul. 16, 2026, which is 6% below its 10-year median of 23.21. GuruFocus rates FRA:RYH0 with a GF Score™ of 36/100. The stock has 3 warning signs investors should review. Among 1,227 Biotechnology companies, Sareum Holdings ranks worse than 94.7% on this metric.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. As of today (2026-07-16), Sareum Holdings's share price is €0.218. Sareum Holdings's Book Value per Share for the quarter that ended in Dec. 2025 was €0.01. Hence, Sareum Holdings's PB Ratio of today is 21.80.
Warning Sign:
Sareum Holdings PLC stock PB Ratio (=25.56) is close to 2-year high of 25.56.
The historical rank and industry rank for Sareum Holdings's PB Ratio or its related term are showing as below:
FRA:RYH0'
s PB Ratio Range Over the Past 10 Years
Min: 3.84 Med: 23.21 Max: 158.04
Current: 25.56
During the past 13 years, Sareum Holdings's highest PB Ratio was 158.04. The lowest was 3.84. And the median was 23.21.
FRA:RYH0's PB Ratio is ranked worse than 94.7% of 1227
companies
in the Biotechnology industry
Industry Median: 2.93
vs FRA:RYH0: 25.56
During the past 12 months, Sareum Holdings's average Book Value Per Share Growth Rate was -74.30% per year.
During the past 3 years, the average Book Value Per Share Growth Rate was -35.70% per year.
During the past 5 years, the average Book Value Per Share Growth Rate was -15.90% per year.
During the past 10 years, the average Book Value Per Share Growth Rate was -5.90% per year.
During the past 13 years, the highest 3-Year average Book Value Per Share Growth Rate of Sareum Holdings was 49.90% per year. The lowest was -50.00% per year. And the median was -14.00% per year.
The PB Ratio works the best for the businesses that earn most of their profit from their assets, e.g. banks and insurance companies.
Be Aware
Some businesses have very light assets, such as software companies or insurance agencies. The PB Ratio does not work well for these companies. Some companies even have negative equity, so the PB Ratio cannot be applied to them.
Sareum Holdings PB Ratio Related Terms
Sareum Holdings PB Ratio Historical Data
* Premium members only.
The historical data trend for Sareum Holdings's PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Sareum Holdings's PB Ratio, along with its competitors' market caps and PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Sareum Holdings PB Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Sareum Holdings's PB Ratio distribution charts can be found below:
* The bar in red indicates where Sareum Holdings's PB Ratio falls into.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. It is a ratio widely used to value stocks.
Sareum Holdings's PB Ratio for today is calculated as follows:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
It can also be calculated from the numbers for the whole company:
A closely related ratio is called Price-to-Tangible-Book. The difference between Price-to-Tangible-Book and PB Ratio is that book value other than intangibles are used in the calculation.
Sareum Holdings (FRA:RYH0) has a PB Ratio of 21.80 as of Jul. 16, 2026. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Sareum Holdings and its competitors. This is near median its historical median of 23.21. Over the past decade, Sareum Holdings' PB Ratio has ranged from 3.84 to 158.04. According to the industry distribution chart, Sareum Holdings ranks #1162 out of 1227 companies in the Biotechnology industry, placing it in the top 94.7%.
Is Sareum Holdings' PB Ratio too high?
Sareum Holdings' current PB Ratio of 21.80 is near median its 10-year median of 23.21. Over the past 10 years, this metric has ranged from a low of 3.84 to a high of 158.04. The Biotechnology industry median PB Ratio is 2.93. Sareum Holdings' value of 21.80 is 644% above this industry median. Based on the distribution chart, Sareum Holdings ranks #1162 out of 1227 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Sareum Holdings has a GF Score™ of 36/100, reflecting its overall financial health beyond just this single metric.
How does Sareum Holdings' PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Sareum Holdings ranks #1162 out of 1227 companies for PB Ratio. This places Sareum Holdings in the lower half of its industry. The industry median PB Ratio is 2.93. Sareum Holdings' value of 21.80 is 644% above this benchmark. Historically, Sareum Holdings' own PB Ratio has ranged from 3.84 to 158.04 over the past decade. While the company's 10-year median is 23.21 vs. the industry median of 2.93, Sareum Holdings has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good PB Ratio for a Biotechnology company?
The median PB Ratio among Biotechnology companies is 2.93, based on 1,227 companies in the industry. Companies in the top quartile (top 25%) have a PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Sareum Holdings's current PB Ratio of 21.80 is 644% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high PB Ratio mean?
A high PB Ratio can signal that a stock is expensive relative to its fundamentals. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Sareum Holdings and its competitors. For the Biotechnology industry, the median PB Ratio is 2.93 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Sareum Holdings's current PB Ratio is 21.80, which is near median its own 10-year median of 23.21. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Sareum Holdings stock overvalued right now?
Sareum Holdings (FRA:RYH0) has a current PB Ratio of 21.80. The current PB Ratio is 21.80, which is near median its 10-year median of 23.21 and 644% above the Biotechnology industry median of 2.93. Sareum Holdings' overall GF Score™ is 36/100 with 3 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is PB Ratio calculated?
PB Ratio is calculated from a company's financial statements. For Sareum Holdings (FRA:RYH0), the current PB Ratio is 21.80 as of Jul. 16, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Sareum Holdings PLC is engaged in drug discovery and development. The company is focused on cancer and autoimmune diseases and licensing them to pharmaceutical and biotechnology companies. The company's drug pipeline includes SDC-1801 for autoimmune diseases, SDC-1802 for cancers, SRA737 targeting solid tumors among others.
36GF Score
Get the complete analysis for FRA:RYH0
PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
FRA:RYH0 has been successfully added to your 
