Focused on building reliable datasets, financial models, and research tools for value-minded investors. Committed to turning complex data into practical guidance for value-investing and long-term wealth.
Dr. Charlie Tian is the founder and CEO of GuruFocus.com, a leading global investment research platform established in 2004. With a Ph.D. in physics, Dr. Tian transitioned from science to finance, applying a data-driven, disciplined approach to value investing.
Circio Holding ASALTS:0RIS +1.53%17 PB Ratio is 7.01 as of Sep. 02, 2026, which is 367% above its 10-year median of 1.50. GuruFocus rates LTS:0RIS with a GF Score™ of 17/100. The stock has 4 warning signs investors should review. Among 1,218 Biotechnology companies, Circio Holding ASA ranks worse than 76.19% on this metric.
Circio Holding ASA stock PB Ratio (=6.42) is close to 3-year low of 6.42.
The historical rank and industry rank for Circio Holding ASA's PB Ratio or its related term are showing as below:
LTS:0RIS'
s PB Ratio Range Over the Past 10 Years
Min: 0.29 Med: 1.5 Max: 80.14
Current: 6.42
During the past 13 years, Circio Holding ASA's highest PB Ratio was 80.14. The lowest was 0.29. And the median was 1.50.
LTS:0RIS's PB Ratio is ranked worse than 76.19% of 1218
companies
in the Biotechnology industry
Industry Median: 2.945
vs LTS:0RIS: 6.42
During the past 13 years, the highest 3-Year average Book Value Per Share Growth Rate of Circio Holding ASA was 914.40% per year. The lowest was -84.70% per year. And the median was -22.80% per year.
The PB Ratio works the best for the businesses that earn most of their profit from their assets, e.g. banks and insurance companies.
Be Aware
Some businesses have very light assets, such as software companies or insurance agencies. The PB Ratio does not work well for these companies. Some companies even have negative equity, so the PB Ratio cannot be applied to them.
Circio Holding ASA PB Ratio Related Terms
Circio Holding ASA PB Ratio Historical Data
* Premium members only.
The historical data trend for Circio Holding ASA's PB Ratio can be seen below:
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
For the Biotechnology subindustry, Circio Holding ASA's PB Ratio, along with its competitors' market caps and PB Ratio data, can be viewed below:
* Competitive companies are chosen from companies within the same industry, with headquarter located in same country, with closest market capitalization; x-axis shows the market cap, and y-axis shows the term value; the bigger the dot, the larger the market cap. Note that "N/A" values will not show up in the chart.
Circio Holding ASA PB Ratio vs Biotechnology Industry
For the Biotechnology industry and Healthcare sector, Circio Holding ASA's PB Ratio distribution charts can be found below:
* The bar in red indicates where Circio Holding ASA's PB Ratio falls into.
The PB Ratio, or Price-to-Book ratio, or Price/Book, is a financial ratio used to compare a company's market price to its Book Value per Share. It is a ratio widely used to value stocks.
* For Operating Data section: All numbers are indicated by the unit behind each term and all currency related amount are in USD. * For other sections: All numbers are in millions except for per share data, ratio, and percentage. All currency related amount are indicated in the company's associated stock exchange currency.
It can also be calculated from the numbers for the whole company:
A closely related ratio is called Price-to-Tangible-Book. The difference between Price-to-Tangible-Book and PB Ratio is that book value other than intangibles are used in the calculation.
Circio Holding ASA (LTS:0RIS) has a PB Ratio of 7.01 as of Sep. 02, 2026. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Circio Holding ASA and its competitors. This is 367% above median its historical median of 1.50. Over the past decade, Circio Holding ASA's PB Ratio has ranged from 0.29 to 80.14. According to the industry distribution chart, Circio Holding ASA ranks #928 out of 1218 companies in the Biotechnology industry, placing it in the top 76.2%.
Is Circio Holding ASA's PB Ratio too high?
Circio Holding ASA's current PB Ratio of 7.01 is 367% above median its 10-year median of 1.50. Over the past 10 years, this metric has ranged from a low of 0.29 to a high of 80.14. The Biotechnology industry median PB Ratio is 2.95. Circio Holding ASA's value of 7.01 is 138% above this industry median. Based on the distribution chart, Circio Holding ASA ranks #928 out of 1218 companies in the Biotechnology industry, which is in the bottom quartile relative to peers. Overall, Circio Holding ASA has a GF Score™ of 17/100, reflecting its overall financial health beyond just this single metric.
How does Circio Holding ASA's PB Ratio compare to VRTX and REGN?
According to the Biotechnology industry distribution chart, Circio Holding ASA ranks #928 out of 1218 companies for PB Ratio. This places Circio Holding ASA in the lower half of its industry. The industry median PB Ratio is 2.95. Circio Holding ASA's value of 7.01 is 138% above this benchmark. Historically, Circio Holding ASA's own PB Ratio has ranged from 0.29 to 80.14 over the past decade. While the company's 10-year median is 1.50 vs. the industry median of 2.95, Circio Holding ASA has consistently been above the industry average. See the competitive comparison table and distribution chart on this page for a detailed peer-by-peer breakdown.
What is a good PB Ratio for a Biotechnology company?
The median PB Ratio among Biotechnology companies is 2.95, based on 1,218 companies in the industry. Companies in the top quartile (top 25%) have a PB Ratio significantly above this median, while those in the bottom quartile fall well below. However, PB Ratio should not be evaluated in isolation — investors should consider it alongside profitability, growth, and financial strength metrics. Circio Holding ASA's current PB Ratio of 7.01 is 138% above the industry median. Use the industry distribution chart on this page to see where any company falls relative to its peers.
What does a high PB Ratio mean?
A high PB Ratio can signal that a stock is expensive relative to its fundamentals. Price-to-Book ratio is the ratio of share price to a company's book value per share. View historical data on Circio Holding ASA and its competitors. For the Biotechnology industry, the median PB Ratio is 2.95 — values significantly above this may indicate overvaluation, while values below may suggest a bargain or underlying issues. Circio Holding ASA's current PB Ratio is 7.01, which is 367% above median its own 10-year median of 1.50. However, context matters — high-growth companies often justify higher valuations. Always evaluate alongside other metrics like GF Score™ and GF Value™.
Is Circio Holding ASA stock overvalued right now?
Circio Holding ASA (LTS:0RIS) has a current PB Ratio of 7.01. The current PB Ratio is 7.01, which is 367% above median its 10-year median of 1.50 and 138% above the Biotechnology industry median of 2.95. Circio Holding ASA's overall GF Score™ is 17/100 with 4 warning signs to review. Investors should evaluate multiple metrics — including profitability, growth, and financial strength — before making a decision.
How is PB Ratio calculated?
PB Ratio is calculated from a company's financial statements. For Circio Holding ASA (LTS:0RIS), the current PB Ratio is 7.01 as of Sep. 02, 2026. GuruFocus calculates this using data sourced from SEC filings and annual reports. See the calculation section and 30-year financial data on this page for the full breakdown.
Circio Holding ASA is a biotechnology company developing circular RNA expression technology for gene and cell therapy applications. It has developed a circular RNA (circRNA) vector expression platform known as circVec, which is based on modular genetic constructs designed for circRNA production within target cells. The platform is being developed for applications including genetic medicine, cell therapy, and chronic disease treatment. The company's activities also include the development of RNA, DNA, and viral therapeutic technologies related to gene expression and protein production.
17GF Score
Get the complete analysis for LTS:0RIS
PB Ratio is just one metric. See GF Value™, 30-year financials, guru trades, warning signs, and more.
Quick Browse
Personalize
Premium Gurus 
Create New Portfolio
LTS:0RIS has been successfully added to your 
